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References from Therapeutic potential of haptoglobin in a murine model of sickle cell anemia. Local targets link to admitted publications; unresolved targets remain external evidence.
In utero therapy for the treatment of sickle cell disease: taking advantage of the fetal immune system
10.3389/fcell.2020.624477 · 2021 · External reference
Sickle cell anemia
10.1148/radiographics.21.4.g01jl23971 · 2001 · External reference
Treating sickle cell anemia
10.1126/science.aba3827 · 2020 · External reference
Unresolved reference
2013 · External reference
Probable assignment of the alpha locus of haptoglobin to chromome 16 in man
10.1038/2231163a0 · 1969 · External reference
Haptoglobin: from hemoglobin scavenging to human health
10.1016/j.mam.2020.100851 · 2020 · External reference
The haptoglobin-CD163-heme oxygenase-1 pathway for hemoglobin scavenging
10.1155/2013/523652 · 2013 · External reference
Unresolved reference
External reference
CD163 is the macrophage scavenger receptor for native and chemically modified hemoglobins in the absence of haptoglobin
10.1182/blood-2005-03-1014 · 2006 · External reference
Heme degradation in pathophysiology of and countermeasures to inflammation-associated disease
10.3390/ijms21249698 · 2020 · External reference
Significance of heme and heme degradation in the pathogenesis of acute lung and inflammatory disorders
10.3390/ijms22115509 · 2021 · External reference
Haptoglobin
10.1089/ars.2016.6793 · 2017 · External reference
Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease
10.1038/nm1202-799 · 2002 · External reference
Mouse models of bone marrow transplantation
10.1016/j.bbmt.2007.10.021 · 2008 · External reference
Transgenic knockout mice with exclusively human sickle hemoglobin and sickle cell disease
10.1126/science.278.5339.876 · 1997 · External reference
A knockout of a transgenic mouse--animal models of sickle cell anemia
10.1056/nejm199807163390310 · 1998 · External reference
Mouse models of sickle cell disease: imperfect and yet very informative
10.1016/j.bcmd.2023.102776 · 2024 · External reference
Effects of mixed hematopoietic chimerism in a mouse model of bone marrow transplantation for sickle cell anemia
10.1182/blood.v97.12.3960 · 2001 · External reference
Sickle cell disease: progress towards combination drug therapy
10.1111/bjh.17312 · 2021 · External reference
Treatment options for sickle cell disease
10.1016/j.pcl.2018.01.005 · 2018 · External reference
Hematopoietic stem cell gene-addition/editing therapy in sickle cell disease
10.3390/cells11111843 · 2022 · External reference
Intravenous infusion of haptoglobin for the prevention of adverse clinical outcome in sickle cell disease
10.1016/j.mehy.2015.06.023 · 2015 · External reference
Haptoglobin degradation product as a novel serum biomarker for hematopoietic stem cell transplant-associated thrombotic microangiopathy
10.1007/s00467-018-4178-x · 2019 · External reference
Haptoglobin therapeutics and compartmentalization of cell-free hemoglobin toxicity
10.1016/j.molmed.2020.02.004 · 2020 · External reference
Apohemoglobin-haptoglobin complex alleviates iron toxicity in mice with β-thalassemia via scavenging of cell-free hemoglobin and heme
10.1016/j.biopha.2022.113911 · 2022 · External reference
Accelerated atherosclerosis in beta-thalassemia
10.1152/ajpheart.00306.2023 · 2023 · External reference
Haptoglobin: basic and clinical aspects
10.1089/ars.2009.2793 · 2010 · External reference
Cationic liposome-mediated gene delivery to the liver and to hepatocellular carcinomas in mice
10.1089/104303401750148748 · 2001 · External reference
Considering the spleen in sickle cell disease
10.1080/17474086.2019.1627192 · 2019 · External reference
Splenic morphological changes are accompanied by altered baseline immunity in a mouse model of sickle-cell disease
10.1016/j.ajpath.2012.07.034 · 2012 · External reference
Transgenic sickle mice are markedly sensitive to renal ischemia-reperfusion injury
10.1016/s0002-9440(10)62318-8 · 2005 · External reference
Sustained treatment of sickle cell mice with haptoglobin increases HO-1 and H-ferritin expression and decreases iron deposition in the kidney without improvement in kidney function
10.1111/bjh.14280 · 2016 · External reference
Haptoglobin degradation product as a novel serum biomarker for hematopoietic stem cell transplant-associated thrombotic microangiopathy
10.1007/s00467-018-4178-x · ExternalCitation · doi-reference
Splenic morphological changes are accompanied by altered baseline immunity in a mouse model of sickle-cell disease
10.1016/j.ajpath.2012.07.034 · ExternalCitation · doi-reference
Mouse models of bone marrow transplantation
10.1016/j.bbmt.2007.10.021 · ExternalCitation · doi-reference
Mouse models of sickle cell disease: imperfect and yet very informative
10.1016/j.bcmd.2023.102776 · ExternalCitation · doi-reference
Apohemoglobin-haptoglobin complex alleviates iron toxicity in mice with β-thalassemia via scavenging of cell-free hemoglobin and heme
10.1016/j.biopha.2022.113911 · ExternalCitation · doi-reference
Haptoglobin: from hemoglobin scavenging to human health
10.1016/j.mam.2020.100851 · ExternalCitation · doi-reference
Intravenous infusion of haptoglobin for the prevention of adverse clinical outcome in sickle cell disease
10.1016/j.mehy.2015.06.023 · ExternalCitation · doi-reference
Haptoglobin therapeutics and compartmentalization of cell-free hemoglobin toxicity
10.1016/j.molmed.2020.02.004 · ExternalCitation · doi-reference
Treatment options for sickle cell disease
10.1016/j.pcl.2018.01.005 · ExternalCitation · doi-reference
Transgenic sickle mice are markedly sensitive to renal ischemia-reperfusion injury
10.1016/s0002-9440(10)62318-8 · ExternalCitation · doi-reference
Probable assignment of the alpha locus of haptoglobin to chromome 16 in man
10.1038/2231163a0 · ExternalCitation · doi-reference
Cell-free hemoglobin limits nitric oxide bioavailability in sickle-cell disease
10.1038/nm1202-799 · ExternalCitation · doi-reference
A knockout of a transgenic mouse--animal models of sickle cell anemia
10.1056/nejm199807163390310 · ExternalCitation · doi-reference
Considering the spleen in sickle cell disease
10.1080/17474086.2019.1627192 · ExternalCitation · doi-reference
Cationic liposome-mediated gene delivery to the liver and to hepatocellular carcinomas in mice
10.1089/104303401750148748 · ExternalCitation · doi-reference
Haptoglobin: basic and clinical aspects
10.1089/ars.2009.2793 · ExternalCitation · doi-reference
Haptoglobin
10.1089/ars.2016.6793 · ExternalCitation · doi-reference
Sustained treatment of sickle cell mice with haptoglobin increases HO-1 and H-ferritin expression and decreases iron deposition in the kidney without improvement in kidney function
10.1111/bjh.14280 · ExternalCitation · doi-reference
Sickle cell disease: progress towards combination drug therapy
10.1111/bjh.17312 · ExternalCitation · doi-reference
Transgenic knockout mice with exclusively human sickle hemoglobin and sickle cell disease
10.1126/science.278.5339.876 · ExternalCitation · doi-reference
Treating sickle cell anemia
10.1126/science.aba3827 · ExternalCitation · doi-reference
Sickle cell anemia
10.1148/radiographics.21.4.g01jl23971 · ExternalCitation · doi-reference
Accelerated atherosclerosis in beta-thalassemia
10.1152/ajpheart.00306.2023 · ExternalCitation · doi-reference
The haptoglobin-CD163-heme oxygenase-1 pathway for hemoglobin scavenging
10.1155/2013/523652 · ExternalCitation · doi-reference
CD163 is the macrophage scavenger receptor for native and chemically modified hemoglobins in the absence of haptoglobin
10.1182/blood-2005-03-1014 · ExternalCitation · doi-reference
Effects of mixed hematopoietic chimerism in a mouse model of bone marrow transplantation for sickle cell anemia
10.1182/blood.v97.12.3960 · ExternalCitation · doi-reference
In utero therapy for the treatment of sickle cell disease: taking advantage of the fetal immune system
10.3389/fcell.2020.624477 · ExternalCitation · doi-reference
Hematopoietic stem cell gene-addition/editing therapy in sickle cell disease
10.3390/cells11111843 · ExternalCitation · doi-reference
Heme degradation in pathophysiology of and countermeasures to inflammation-associated disease
10.3390/ijms21249698 · ExternalCitation · doi-reference
Significance of heme and heme degradation in the pathogenesis of acute lung and inflammatory disorders
10.3390/ijms22115509 · ExternalCitation · doi-reference
