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References from Assessment of epithelial barrier integrity in cellular monolayer models using low cost, clinically approved fluorescent contrast agents. Local targets link to admitted publications; unresolved targets remain external evidence.
Intestinal barrier in human health and disease
10.3390/ijerph182312836 · 2021 · External reference
Role of gut-brain axis, gut microbial composition, and probiotic intervention in Alzheimer’s disease
10.1016/j.lfs.2020.118627 · 2021 · External reference
Regional specialization within the intestinal immune system
10.1038/nri3738 · 2014 · External reference
Relationships of gut microbiota, short-chain fatty acids, inflammation, and the gut barrier in Parkinson’s disease
10.1186/s13024-021-00427-6 · 2021 · External reference
Leaky gut and autoimmunity: an intricate balance in individuals health and the diseased state
10.3390/ijms21249770 · 2020 · External reference
Gut barrier structure, mucosal immunity and intestinal microbiota in the pathogenesis and treatment of HIV infection
10.1186/s12981-016-0103-1 · 2016 · External reference
Complexification of in vitro models of intestinal barriers, a true challenge for a more accurate alternative approach
10.3390/ijms24043595 · 2023 · External reference
Evaluation of Caco-2 and human intestinal epithelial cells as in vitro models of colonic and small intestinal integrity
2022 · External reference
Disruption of gut barrier integrity and host-microbiome interactions underlie MASLD severity in patients with type-2 diabetes mellitus
10.1080/19490976.2024.2304157 · 2024 · External reference
10.1364/translational.2022.ts2b.6
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Expression of cytochrome P-450 3A in HT29-MTX cells and Caco-2 clone TC7
10.1016/0014-5793(94)01199-0 · 1994 · External reference
Improved transport and absorption through gastrointestinal tract by PEGylated solid lipid nanoparticles
10.1021/mp300649z · 2013 · External reference
Intestinal in vitro cell culture models and their potential to study the effect of food components on intestinal inflammation
10.1080/10408398.2018.1506734 · 2019 · External reference
Exploring the usefulness of the complex in vitro intestinal epithelial model Caco-2/HT29/Raji-B in nanotoxicology
10.1016/j.fct.2018.01.042 · 2018 · External reference
Gut organoids: mini-tissues in culture to study intestinal physiology and disease
10.1152/ajpcell.00300.2017 · 2019 · External reference
Microfluidic organ-on-a-chip models of human intestine
10.1016/j.jcmgh.2017.12.010 · 2018 · External reference
Organs-on-chips with integrated electrodes for trans-epithelial electrical resistance (TEER) measurements of human epithelial barrier function
10.1039/c7lc00155j · 2017 · External reference
Bioengineered human colon organoids with in vivo-like cellular complexity and function. Cell Stem Cell
External reference
Head-to-head comparison of Caco-2 Transwell and gut-on-a-chip models for assessing oral peptide formulations
10.1021/acs.molpharmaceut.4c00210 · 2024 · External reference
Use of the lactulose to mannitol ratio to evaluate childhood environmental enteric dysfunction: a systematic review
10.1093/cid/ciu541 · 2014 · External reference
A case for improved assessment of gut permeability: a meta-analysis quantifying the lactulose:mannitol ratio in coeliac and Crohn’s disease
10.1186/s12876-021-02082-z · 2022 · External reference
Transcutaneous fluorescence spectroscopy as a tool for non-invasive monitoring of gut function: first clinical experiences
10.1038/s41598-020-73149-2 · 2020 · External reference
Transcutaneous fluorescence spectroscopy: development and characterization of a compact, portable, and fiber-optic sensor
10.1117/1.jbo.29.2.027003 · 2024 · External reference
Rapid testing of gut permeability using oral fluorescein and confocal laser endomicroscopy in Zambian adults
10.1093/trstmh/trab083 · 2021 · External reference
Non-invasive assessment of intestinal permeability in healthy volunteers using transcutaneous fluorescence spectroscopy
2022 · External reference
Non-invasive fluorescence sensing reveals changes in intestinal barrier function and gastric emptying rate in a first-in-human study of Crohn’s disease
10.1177/17562848251361634 · 2025 · External reference
Non-invasive measurement of intestinal barrier function in environmental enteropathy using transcutaneous fluorescence sensing
10.1136/gutsci-2025-000011 · 2026 · External reference
TEER measurement techniques for in vitro barrier model systems
10.1177/2211068214561025 · 2015 · External reference
Methylene Blue Inhibits Caspases by Oxidation of the Catalytic Cysteine
10.1038/srep13730 · 2015 · External reference
Cytotoxic effect and apoptosis pathways activated by methylene blue-mediated photodynamic therapy in fibroblasts
10.1016/j.pdpdt.2020.101654 · 2020 · External reference
Methylene blue induces cytotoxicity in human brain tumor cells
10.1016/0304-3835(94)03629-w · 1995 · External reference
Methylene blue-mediated Photodynamic Therapy in human retinoblastoma cell lines
10.1016/j.jphotobiol.2021.112260 · 2021 · External reference
Fluorescent artificial receptor-based membrane assay (FARMA) for spatiotemporally resolved monitoring of biomembrane permeability
10.1038/s42003-020-1108-9 · 2020 · External reference
Nanofibrous Scaffolds Support a 3D in vitro Permeability Model of the Human Intestinal Epithelium
10.3389/fphar.2019.00456 · 2019 · External reference
Lucifer Yellow - A Robust Paracellular Permeability Marker in a Cell Model of the Human Blood-brain Barrier
2019 · External reference
Assessing Mixture Effects of Cereulide and Deoxynivalenol on Intestinal Barrier Integrity and Uptake in Differentiated Human Caco-2 Cells
10.3390/toxins13030189 · 2021 · External reference
Development of a serum-free co-culture of human intestinal epithelium cell-lines (Caco-2/HT29-5M21)
10.1186/1471-2121-7-20 · 2006 · External reference
Type 1 diabetes human enteroid studies reveal major changes in the intestinal epithelial compartment
10.1038/s41598-024-62282-x · 2024 · External reference
Comparison of brain capillary endothelial cell-based and epithelial (MDCK-MDR1, Caco-2, and VB-Caco-2) cell-based surrogate blood-brain barrier penetration models
10.1016/j.ejpb.2012.07.020 · 2012 · External reference
A novel dual-flow bioreactor simulates increased fluorescein permeability in epithelial tissue barriers
10.1002/biot.201400004 · 2014 · External reference
The prediction of human skin responses by using the combined in vitro fluorescein leakage/Alamar Blue (resazurin) assay
10.1177/026119290203000503 · 2002 · External reference
Correction: Endomicroscopic and Transcriptomic Analysis of Impaired Barrier Function and Malabsorption in Environmental Enteropathy
10.1371/journal.pntd.0010505 · 2022 · External reference
Intestinal Biopsies for the Evaluation of Environmental Enteropathy and Environmental Enteric Dysfunction
10.1093/infdis/jiab372 · 2021 · External reference
Ethanol modulation of intestinal epithelial tight junction barrier
1999 · External reference
Epithelium dynamics differ in time and space when exposed to the permeation enhancers penetramax and EGTA. A head-to-head mechanistic comparison
10.3389/fddev.2023.1221628 · 2023 · External reference