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References from Multi-omics integration reveals tissue-specific biosynthesis of sesquiterpenoids in the medicinal plant Eupatorium lindleyanum. Local targets link to admitted publications; unresolved targets remain external evidence.
The genus Eupatorium L. (Asteraceae): A review of their antimicrobial activity
10.5897/jmpr2016.6313 · 2017 · External reference
Integrative metabolomic and transcriptomic analyses reveal flavonoid biosynthesis pathway in Eupatorium lindleyanum
10.1038/s41598-025-27287-0 · 2025 · External reference
Eupatorium lindleyanum DC Ameliorates Carbon Tetrachloride-Induced Hepatic Inflammation and Fibrotic Response in Mice
10.3390/ph18081228 · 2025 · External reference
Comprehensive Comparison of Three Different Medicinal Parts of Eupatorium lindleyanum DC. Using the RRLC-Q-TOF-MS-Based Metabolic Profile and In Vitro Anti-Inflammatory Activity
10.3390/molecules29153551 · 2024 · External reference
Chemical constituents and their bioactivities of plants from the genus Eupatorium (2015-present)
2024 · External reference
Qualitative and quantitative analysis of chemical components in Eupatorium lindleyanum DC. by ultra-performance liquid chromatography-mass spectrometry integrated with anti-inflammatory activity research
10.1002/jssc.202100208 · 2021 · External reference
Eupatorium lindleyanum DC. sesquiterpenes fraction attenuates lipopolysaccharide-induced acute lung injury in mice
10.1016/j.jep.2016.03.022 · 2016 · External reference
Eupalinilide B as a novel anti-cancer agent that inhibits proliferation and epithelial-mesenchymal transition in laryngeal cancer cells
10.1177/03000605211067921 · 2022 · External reference
Traditional Applications, Phytochemistry, and Pharmacological Activities of Eupatorium lindleyanum DC.: A Comprehensive Review
2020 · External reference
Multi-omic analysis highlights new candidate genes involved in triterpenoid and sesquiterpenoid biosynthesis in Codonopsis pilosula (Franch.) Nannf
10.1016/j.indcrop.2025.120685 · 2025 · External reference
Integrated analysis of terpenoid profiles and full-length transcriptome reveals the central pathways of sesquiterpene biosynthesis in Atractylodes chinensis (DC.) Koidz
10.3390/ijms26031074 · 2025 · External reference
An independent biosynthetic route to frame a xanthanolide-type sesquiterpene lactone in Asteraceae
2025 · External reference
Biosynthesis of bridged tricyclic sesquiterpenes in Inula lineariifolia
10.1111/tpj.17008 · 2024 · External reference
Evolution of terpene synthases in the sesquiterpene biosynthesis pathway and analysis of their transcriptional regulatory network in Asteraceae
10.1093/hr/uhaf229 · 2025 · External reference
Tissue specific expression and genomic organization of bitter sesquiterpene lactone biosynthesis in Cichorium intybus L. (Asteraceae)
10.1016/j.indcrop.2018.12.011 · 2019 · External reference
Integrating multiomics data accelerates elucidation of plant primary and secondary metabolic pathways
10.1007/s42994-022-00091-4 · 2023 · External reference
Integrated multiomics profiling elucidates the spatiotemporal metabolic dynamics and regulatory networks of the bioactive components of Trichosanthes kirilowii
10.3389/fpls.2026.1735703 · 2026 · External reference
Combined metabolomic and transcriptomic analysis reveals the key genes for triterpenoid biosynthesis in Cyclocarya paliurus
10.1186/s12864-024-11125-0 · 2024 · External reference
Integration of transcriptomics and metabolomics provides insights into secondary cell wall deposition and terpenoid biosynthesis during stem development in Camphora officinarum
10.1186/s12864-025-12266-6 · 2025 · External reference
Integrated omics profiles for exploring the potential mechanism underlying aroma formation in the terpenoid-rich aromatic plant Opisthopappus taihangensis and the bioactivity of its leaf essential oil
10.1016/j.agrcom.2024.100061 · 2024 · External reference
Multi-omics integration reveals organ-specific biosynthesis of flavonoids and terpenoids in the medicinal plant Bidens alba
10.3389/fpls.2025.1675432 · 2025 · External reference
Harvest time optimization for medicinal and aromatic plant secondary metabolites
10.1016/j.plaphy.2024.108735 · 2024 · External reference
Multi-omics analyses reveal regulatory networks underpinning metabolite biosynthesis in Nicotiana tabacum
10.1038/s41467-025-65299-6 · 2025 · External reference
Integrated metabolomic and transcriptomic analysis of metabolic diversity and biosynthesis of glucosinolates and flavonoids in various cultivars of radish microgreens
10.1016/j.fbio.2024.104055 · 2024 · External reference
Integrative transcriptomic and metabolomic analysis of Drynaria roosii reveals genes involved in the biosynthesis of medicinal compounds
10.1038/s41598-026-39037-x · 2026 · External reference
Integrated transcriptomics and metabolomics analysis provide insight into anthocyanin biosynthesis for sepal color formation in Heptacodium miconioides
10.3389/fpls.2023.1044581 · 2023 · External reference
Integrative transcriptomic and metabolomic analysis reveals the molecular basis of leaf variegation in Cymbidium ensifolium
10.3389/fpls.2026.1712811 · 2026 · External reference
A comparative study of three nucleic acid integrity assay systems
10.1089/bio.2022.0171 · 2023 · External reference
fastp: an ultra-fast all-in-one FASTQ preprocessor
10.1093/bioinformatics/bty560 · 2018 · External reference
Integrative metabolomic and transcriptomic analyses reveal mechanisms of hexavalent chromium toxicity in contrasting rapeseed cultivars
10.3390/agronomy15122892 · 2025 · External reference
iTAK: A program for genome-wide prediction and classification of plant transcription factors, transcriptional regulators, and protein kinases
10.1016/j.molp.2016.09.014 · 2016 · External reference
WGCNA: An R package for weighted correlation network analysis
10.1186/1471-2105-9-559 · 2008 · External reference
Isoalantolactone: A review on its pharmacological effects
2024 · External reference
Targeting PBK with small-molecule 1-O-acetyl-4R,6S-britannilactone for the treatment of neuroinflammation
10.1073/pnas.2502593122 · 2025 · External reference
Eupalinolide B alleviates rheumatoid arthritis through the promotion of apoptosis and autophagy via regulating the AMPK/mTOR/ULK-1 signaling axis
10.1016/j.intimp.2025.114179 · 2025 · External reference
Inhibition of LPS-induced NO production and NF-kappaB activation by a sesquiterpene from Saussurea lappa
10.1007/bf02976467 · 2000 · External reference
Induction of apoptosis by yomogin in human promyelocytic leukemic HL-60 cells
10.1248/bpb.27.1106 · 2004 · External reference
Costunolide and dehydrocostus lactone alleviate ulcerative colitis via regulating TLR4, NF-κB and PI3K expression
10.1038/s41598-024-77021-5 · 2024 · External reference
Antinociception caused by the extract of Hedyosmum brasiliense and its active principle, the sesquiterpene lactone 13-hydroxy-8,9-dehydroshizukanolide
10.1055/s-1999-14007 · 1999 · External reference
Potential anti-cancer activities and mechanisms of costunolide and dehydrocostuslactone
10.3390/ijms160510888 · 2015 · External reference
ChemInform abstract: Chlorahololides C—F: A new class of potent and selective potassium channel blockers from Chloranthus holostegius
10.1002/chin.200837167 · 2008 · External reference
Mining, expression, and phylogenetic analysis of volatile terpenoid biosynthesis-related genes in different tissues of ten Elsholtzia species based on transcriptomic analysis
10.1016/j.phytochem.2022.113419 · 2022 · External reference
Integrated transcriptomics and metabolomics uncover the molecular basis of flavonoid accumulation in the rhizomes of two Cymbidium tortisepalum var. longibracteatum cultivars
10.1016/j.scienta.2021.110738 · 2022 · External reference
Chemical constituents of plants from the genus Eupatorium (1904–2014)
2015 · External reference
Transcriptomics analysis investigates sesquiterpenoids accumulation pattern in different tissues of Atractylodes lancea (Thunb.) DC. plantlet
10.1007/s11240-017-1205-8 · 2017 · External reference
Using synthetic biology to understand the function of plant specialized metabolites
10.1146/annurev-arplant-060223-013842 · 2024 · External reference
Chemical characterization and the intrusion through elicitation and Agrobacterium rhizogenes mediated hairy root transformation in Saussurea costus C.B. Clarke
10.1007/s12298-022-01270-9 · 2023 · External reference
NMR based profiling of sesquiterpene lactones in Saussurea lappa roots collected from different location of Western Himalaya
10.1080/14786419.2020.1789635 · 2022 · External reference
Integrated transcriptomic and metabolomic analysis reveals the molecular basis of tissue-specific accumulation of bioactive steroidal alkaloids in Fritillaria unibracteata
10.1016/j.phytochem.2023.113831 · 2023 · External reference
Specialized structures and developmental mechanisms of secondary metabolite-synthesizing organs and tissues in medicinal plants
10.1111/jipb.70133 · 2026 · External reference
Compartmentalization of specialized metabolites across vegetative and reproductive tissues in two sympatric Psychotria species
10.1002/ajb2.16191 · 2023 · External reference
Regulatory mechanisms underlying stress-induced accumulation of plant secondary metabolites
10.1016/j.jarmap.2025.100689 · 2026 · External reference
CYP71P2 regulated by MYB44 modulates oxygenated sesquiterpenoids biosynthesis in Atractylodes lancea
10.1016/j.plaphy.2025.110700 · 2025 · External reference
Isoprenoid biosynthesis in dandelion latex is enhanced by the overexpression of three key enzymes involved in the mevalonate pathway
10.1186/s12870-017-1036-0 · 2017 · External reference
The organ-specific differential roles of rice DXS and DXR, the first two enzymes of the MEP pathway, in carotenoid metabolism in Oryza sativa leaves and seeds
10.1186/s12870-020-02357-9 · 2020 · External reference
Feedback inhibition of deoxy-D-xylulose-5-phosphate synthase regulates the methylerythritol 4-phosphate pathway
10.1074/jbc.m113.464636 · 2013 · External reference
Cloning and Expression Analysis of a Farnesyl Diphosphate Synthase (FPPS) Gene from Chamaemelum nobile
10.15835/nbha45210858 · 2017 · External reference
Functional characterization and transcriptional activity analysis of Dryopteris fragrans farnesyl diphosphate synthase genes
10.3389/fpls.2023.1105240 · 2023 · External reference
Characterization and functional reconstruction of a highly productive germacrene A synthase from Liriodendron chinense
10.1111/pbi.70023 · 2025 · External reference
Terpenoid metabolism in wild-type and transgenic Arabidopsis plants
10.1105/tpc.016253 · 2003 · External reference
Functional characterization of premnaspirodiene oxygenase, a cytochrome P450 catalyzing regio- and stereo-specific hydroxylations of diverse sesquiterpene substrates
10.1074/jbc.m703378200 · 2007 · External reference
Identification of a novel abscisic acid-regulated farnesol dehydrogenase from Arabidopsis
10.1104/pp.110.157784 · 2010 · External reference
Full-length transcriptome analysis of two chemotype and functional characterization of genes related to sesquiterpene biosynthesis in Atractylodes lancea
10.1016/j.ijbiomac.2022.11.210 · 2023 · External reference
Inactivation of the germacrene A synthase genes by CRISPR/Cas9 eliminates the biosynthesis of sesquiterpene lactones in Cichorium intybus L
10.1111/pbi.13670 · 2021 · External reference
Biosynthesis of the sesquiterpene germacrene D in Solidago canadensis: 13C and (2)H labeling studies
10.1016/s0031-9422(02)00068-7 · 2002 · External reference
Deciphering the complexity of terpenoid biosynthesis and its multi-level regulatory mechanism in plants
10.1007/s00344-024-11347-2 · 2024 · External reference
CitAP2.10 activation of the terpene synthase CsTPS1 is associated with the synthesis of (+)-valencene in “Newhall” orange
10.1093/jxb/erw189 · 2016 · External reference
Genome-wide identification and expression analysis of the WRKY transcription factors related to sesquiterpenes biosynthesis in Atractylodes lancea
10.3389/fgene.2025.1551991 · 2025 · External reference
Genome-wide analysis of NAC gene family and function exploration of SaNAC30 in Santalum album L
10.1016/j.indcrop.2025.120827 · 2025 · External reference
Integration of transcriptomics and metabolomics reveals the mechanism of aroma formation during apricot fruit development
10.1016/j.scienta.2025.114351 · 2025 · External reference