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References from Optimised fluorescence-activated nuclei sorting for epigenomic analysis of cortical cell types. Local targets link to admitted publications; unresolved targets remain external evidence.
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection
10.1038/s41588-018-0059-2 · 2018 · External reference
A meta-analysis of epigenome-wide association studies in Alzheimer’s disease highlights novel differentially methylated loci across cortex
10.1038/s41467-021-23243-4 · 2021 · External reference
Schizophrenia-associated methylomic variation: molecular signatures of disease and polygenic risk burden across multiple brain regions
2017 · External reference
Integrative genomics identifies a convergent molecular subtype that links epigenomic with transcriptomic differences in autism
10.1038/s41467-020-18526-1 · 2020 · External reference
Microglia and astrocytes in Alzheimer’s Disease: Implications for therapy
10.2174/1570159x15666170720095240 · 2018 · External reference
Single-cell sequencing of brain cell transcriptomes and epigenomes
10.1016/j.neuron.2020.12.010 · 2021 · External reference
Single-cell sequencing techniques from individual to multiomics analyses
10.1038/s12276-020-00499-2 · 2020 · External reference
Identification of neuronal nuclei (NeuN) as Fox-3, a new member of the Fox-1 gene family of splicing factors
10.1074/jbc.m109.052969 · 2009 · External reference
Neuronal brain-region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability
10.1038/s41593-018-0297-8 · 2019 · External reference
Practical guidelines for high-resolution epigenomic profiling of nucleosomal histones in postmortem human brain tissue
10.1016/j.biopsych.2016.03.1048 · 2017 · External reference
Association of a history of child abuse with impaired myelination in the anterior cingulate cortex: Convergent epigenetic, transcriptional, and morphological evidence
10.1176/appi.ajp.2017.16111286 · 2017 · External reference
Transcriptional profiling of human microglia reveals grey-white matter heterogeneity and multiple sclerosis-associated changes
10.1038/s41467-019-08976-7 · 2019 · External reference
Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10
10.1101/gad.215802 · 2002 · External reference
IRF8 is a critical transcription factor for transforming microglia into a reactive phenotype
10.1016/j.celrep.2012.02.014 · 2012 · External reference
Setd1a Loss-of-function Disrupts Epigenetic Regulation of Ribosomal Genes via Altered DNA Methylation
10.1093/schbul/sbaf091 · 2026 · External reference
fastp: an ultra-fast all-in-one FASTQ preprocessor
10.1093/bioinformatics/bty560 · 2018 · External reference
STAR: ultrafast universal RNA-seq aligner
10.1093/bioinformatics/bts635 · 2013 · External reference
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
10.1186/s13059-014-0550-8 · 2014 · External reference
Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons
10.1038/s41593-020-0621-y · 2020 · External reference
Single-cell genomics identifies cell type-specific molecular changes in autism
10.1126/science.aav8130 · 2019 · External reference
Neuronal vulnerability and multilineage diversity in multiple sclerosis
10.1038/s41586-019-1404-z · 2019 · External reference
Spatial reconstruction of single-cell gene expression data
10.1038/nbt.3192 · 2015 · External reference
Bigmelon: Tools for analysing large DNA methylation datasets
10.1093/bioinformatics/bty713 · 2019 · External reference
Guidance for the design and analysis of cell-type specific epigenetic epidemiology studies
2024 · External reference
Quantifying the proportion of different cell types in the human cortex using DNA methylation profiles
10.1186/s12915-024-01827-y · 2024 · External reference
A data-driven approach to preprocessing Illumina 450K methylation array data
10.1186/1471-2164-14-293 · 2013 · External reference
Unresolved reference
2024 · External reference
An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues
10.1038/nmeth.4396 · 2017 · External reference
Unresolved reference
2010 · External reference
Fast gapped-read alignment with Bowtie 2
10.1038/nmeth.1923 · 2012 · External reference
The Sequence Alignment/Map format and SAMtools
10.1093/bioinformatics/btp352 · 2009 · External reference
Unresolved reference
External reference
Ancestry-agnostic estimation of DNA sample contamination from sequence reads
10.1101/gr.246934.118 · 2020 · External reference
Model-based analysis of ChIP-Seq (MACS)
10.1186/gb-2008-9-9-r137 · 2008 · External reference
The R package Rsubread is easier, faster, cheaper and better for alignment and quantification of RNA sequencing reads
10.1093/nar/gkz114 · 2019 · External reference
CUT&Tag for efficient epigenomic profiling of small samples and single cells
10.1038/s41467-019-09982-5 · 2019 · External reference
Multimodal chromatin profiling using nanobody-based single-cell CUT&Tag
10.1038/s41587-022-01535-4 · 2023 · External reference
Unresolved reference
External reference
Unresolved reference
2023 · External reference
featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
10.1093/bioinformatics/btt656 · 2014 · External reference
The brain neurovascular epigenome and its association with dementia
10.1016/j.neuron.2025.10.001 · 2026 · External reference
A histone acetylome-wide association study of Alzheimer’s disease identifies disease-associated H3K27ac differences in the entorhinal cortex
10.1038/s41593-018-0253-7 · 2018 · External reference
Cell-type-specific DNA methylation dynamics in the prenatal and postnatal human cortex
10.1016/j.xgen.2025.101010 · 2025 · External reference
Neuronal nuclei isolation from human postmortem brain tissue
2008 · External reference
A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain
10.1186/s13195-019-0524-x · 2019 · External reference
Nuclei isolation of multiple brain cell types for omics interrogation
10.1038/s41596-020-00472-3 · 2021 · External reference
NeuN, a neuronal specific nuclear protein in vertebrates
10.1242/dev.116.1.201 · 1992 · External reference