References

Early mutational events and clonal dynamics in normal crypts: Implications for colorectal tumorigenesis

10.1186/s40246-025-00889-5 · 2025 · External reference

Potential of Dendrobium officinale oligosaccharides to alleviate chronic colitis by modulating inflammation and gut microbiota

10.26599/fmh.2025.9420077 · 2025 · External reference

Recapitulating the adenoma-carcinoma sequence by selection of four spontaneous oncogenic mutations in mismatch-repair-deficient human colon organoids

10.1038/s43018-024-00841-x · 2024 · External reference

DG-MSGAT: A Biologically-informed Differential Gene Multi-Scale Graph Attention Network for predicting neoadjuvant therapy response in rectal cancer

10.1016/j.cmpb.2025.108974 · 2025 · External reference

A comprehensive survey on graph neural networks

10.1109/tnnls.2020.2978386 · 2021 · External reference

Integration of multiomics data with graph convolutional networks to identify new cancer genes and their associated molecular mechanisms

10.1038/s42256-021-00325-y · 2021 · External reference

Improving cancer driver gene identification using multi-task learning on graph convolutional network

10.1093/bib/bbab432 · 2022 · External reference

DGMP: Identifying cancer driver genes by jointing DGCN and MLP from multi-omics genomic data

10.1016/j.gpb.2022.11.004 · 2022 · External reference

Analysis of dynamic molecular networks: The progression from colorectal adenoma to cancer

10.21037/jgo-21-674 · 2021 · External reference

The STRING database in 2025: Protein networks with directionality of regulation

10.1093/nar/gkae1113 · 2025 · External reference

Unresolved reference

External reference

Unresolved reference

External reference

Automatic graph topology-aware transformer

10.1109/tnnls.2024.3440269 · 2025 · External reference

GTC: GNN-Transformer co-contrastive learning for self-supervised heterogeneous graph representation

10.1016/j.neunet.2024.106645 · 2025 · External reference

Integrating machine learning and bioinformatics approaches for identifying novel diagnostic gene biomarkers in colorectal cancer

10.1038/s41598-024-75438-6 · 2024 · External reference

Integrated analysis of public datasets for the discovery and validation of survival-associated genes in solid tumors

2024 · External reference

scTenifoldKnk: An efficient virtual knockout tool for gene function predictions via single-cell gene regulatory network perturbation

10.1016/j.patter.2022.100434 · 2022 · External reference

Identification of cancer driver genes by integrating multiomics data with graph neural networks

10.3390/metabo13030339 · 2023 · External reference

Mind your prevalence!

10.1186/s13321-024-00837-w · 2024 · External reference

Targeting extracellular matrix interaction in gastrointestinal cancer: Immune modulation, metabolic reprogramming, and therapeutic strategies

10.1016/j.bbcan.2024.189225 · 2024 · External reference

Extracellular matrix stiffness: Mechanisms in tumor progression and therapeutic potential in cancer

10.1186/s40164-025-00647-2 · 2025 · External reference

Modulating extracellular matrix stiffness: A strategic approach to boost cancer immunotherapy

10.1038/s41419-024-06697-4 · 2024 · External reference

Tumor-associated macrophages restrict CD8+ T cell function through collagen deposition and metabolic reprogramming of the breast cancer microenvironment

10.1038/s43018-024-00775-4 · 2024 · External reference

Metabolic-immune nexus in tumor microenvironment: From mechanistic insights to therapeutic opportunities

10.1097/cm9.0000000000003908 · 2025 · External reference

Metabolic causal factor of immune cell function and fate in the tumor microenvironment

10.1016/j.bulcan.2026.01.008 · 2026 · External reference

The role of adipocytes recruited as part of tumor microenvironment in promoting colorectal cancer metastases

10.3390/ijms25158352 · 2024 · External reference

THBS2 + cancer-associated fibroblasts promote EMT leading to oxaliplatin resistance via COL8A1-mediated PI3K/AKT activation in colorectal cancer

10.1186/s12943-024-02180-y · 2024 · External reference

Atomic force microscopy reveals the influence of substrate collagen concentration and TGF-β on lung fibroblast mechanics

10.1016/j.micron.2024.103751 · 2025 · External reference

ECD-CDGI: An efficient energy-constrained diffusion model for cancer driver gene identification

10.1371/journal.pcbi.1012400 · 2024 · External reference

Long noncoding RNA HOTTIP/HOXA13 expression is associated with disease progression and predicts outcome in hepatocellular carcinoma patients

10.1002/hep.26740 · 2014 · External reference

Discovery of novel diagnostic biomarkers of hepatocellular carcinoma associated with immune infiltration

10.1080/07853890.2025.2503645 · 2025 · External reference

Circular RNA circZNF566 promotes hepatocellular carcinoma progression by sponging miR-4738-3p and regulating TDO2 expression

10.1038/s41419-020-2616-8 · 2020 · External reference

Hepatic stellate cells promote hepatocellular carcinoma development by regulating histone lactylation: Novel insights from single-cell RNA sequencing and spatial transcriptomics analyses

10.1016/j.canlet.2024.217243 · 2024 · External reference

Decreased expression of ApoF associates with poor prognosis in human hepatocellular carcinoma

10.1093/gastro/goz011 · 2019 · External reference

Prognostic implications of alcohol dehydrogenases in hepatocellular carcinoma

10.1186/s12885-020-07689-1 · 2020 · External reference

The prognostic value of CYP2C subfamily genes in hepatocellular carcinoma

10.1002/cam4.1299 · 2018 · External reference

Molecular markers associated with lymph node metastasis in pancreatic ductal adenocarcinoma by genome-wide expression profiling

10.1111/j.1349-7006.2009.01359.x · 2010 · External reference

Targeting pancreatic cancer progression: The formononetin and salvianolic acid B combination suppresses JAK/STAT signaling via MBOAT2 downregulation

10.1016/j.joim.2026.05.003 · 2026 · External reference

SLC6A14-mediated glutamine promotes SYTL4-CXCL8 axis activation to drive gemcitabine resistance and immune evasion in pancreatic cancer

10.1038/s12276-025-01596-w · 2025 · External reference

MUC13-Associated molecular interactome in pancreatic cancer

10.34133/csbj.0056 · 2026 · External reference

Annexin A10 is a candidate marker associated with the progression of pancreatic precursor lesions to adenocarcinoma

2017 · External reference

GALNT5 functions as a suppressor of ferroptosis and a predictor of poor prognosis in pancreatic adenocarcinoma

2023 · External reference

Oleic acid-induced NOX4 is dependent on ANGPTL4 expression to promote human colorectal cancer metastasis

10.7150/thno.44744 · 2020 · External reference

DNA methylation of SFRP1, SFRP2, and WIF1 and prognosis of postoperative colorectal cancer patients

10.1186/s12885-019-6436-0 · 2019 · External reference

STC2+ malignant cell state associated with EMT, tumor microenvironment remodeling, and poor prognosis revealed by single-cell and spatial transcriptomics in colorectal cancer

2025 · External reference

Endothelial cell-derived IGFBP7 suppresses angiogenesis and tumor progression in colorectal cancer via the VAPA-TGF-β1 pathway

10.1186/s13046-026-03664-z · 2026 · External reference

IL-33 facilitates proliferation of colorectal cancer dependent on COX2/PGE2

10.1186/s13046-018-0839-7 · 2018 · External reference

Integrated multidimensional bioinformatics analysis of the molecular mechanisms of ulcerative colitis-associated colorectal cancer and MMP1 as a potential therapeutic target

10.1038/s41417-025-00917-5 · 2025 · External reference

Identification of key claudin genes associated with survival prognosis and diagnosis in colon cancer through integrated bioinformatic analysis

10.3389/fgene.2023.1221815 · 2023 · External reference

Expression, prognosis, immunological infiltration, and DNA methylation of members of the SFRP gene family in colorectal cancer: A comparative bioinformatic and experimental analysis

10.1007/s11626-024-00998-w · 2025 · External reference

Right-side and left-side colon cancer follow different pathways to relapse

10.1002/mc.20804 · 2012 · External reference

Development of a novel prognostic panel for colorectal cancer based on cancer functional status, and validation of STC2 as a promising biomarker

10.31083/j.fbl2907245 · 2024 · External reference

Down-regulation of FN1 inhibits colorectal carcinogenesis by suppressing proliferation, migration, and invasion

10.1002/jcb.26651 · 2018 · External reference

ZDHHC9-mediated KLF5 palmitoylation enhances the cAMP/PKA/CREB axis to promote colorectal cancer progression

10.1038/s41388-026-03724-w · 2026 · External reference

The TRIB3-SQSTM1 interaction mediates metabolic stress-promoted tumorigenesis and progression via suppressing autophagic and proteasomal degradation

10.1080/15548627.2015.1084458 · 2015 · External reference

Epigenetic control of topoisomerase 1 activity presents a cancer vulnerability

10.1038/s41467-025-62598-w · 2025 · External reference

GNNExplainer: Generating explanations for graph neural networks

2019 · External reference

Palmitic acid activates c-Myc via dual palmitoylation-dependent pathways to promote colon cancer

10.1038/s41421-026-00869-6 · 2026 · External reference

Gene expression analyses identify a relationship between stanniocalcin 2 and the malignant behavior of colorectal cancer

10.2147/ott.s167780 · 2018 · External reference

IGFBP7, a novel tumor stroma marker, with growth-promoting effects in colon cancer through a paracrine tumor-stroma interaction

10.1038/onc.2014.18 · 2015 · External reference

Expression changes of cell-cell adhesion-related genes in colorectal tumors

10.3892/ol.2015.3107 · 2015 · External reference

Food and medicine homology in cancer treatment: Traditional thoughts collide with scientific evidence

10.26599/fmh.2025.9420120 · 2025 · External reference

Social network analysis of cell networks improves deep learning for prediction of molecular pathways and key mutations in colorectal cancer

10.1016/j.media.2023.103071 · 2024 · External reference