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References from Enterococcal cell wall remodelling underpins pathogenesis via the release of the Enteroccocal Polysaccharide Antigen (EPA). Local targets link to admitted publications; unresolved targets remain external evidence.
Peptidoglycan structure and architecture
10.1111/j.1574-6976.2007.00094.x · 2008 · External reference
Bagshaped macromolecules--a new outlook on bacterial cell walls
1964 · External reference
The structure of secondary cell wall polymers: how Gram-positive bacteria stick their cell walls together
10.1099/mic.0.27749-0 · 2005 · External reference
Regulation of peptidoglycan synthesis and remodelling
10.1038/s41579-020-0366-3 · 2020 · External reference
Regulation of peptidoglycan hydrolases: localization, abundance, and activity
10.1016/j.mib.2023.102279 · 2023 · External reference
Role of N-acetylglucosaminidase and N-acetylmuramidase activities in Enterococcus faecalis peptidoglycan metabolism
10.1074/jbc.m802323200 · 2008 · External reference
Effect of disruption of a gene encoding an autolysin of Enterococcus faecalis OG1RF
10.1128/aac.42.11.2883 · 1998 · External reference
A moonlighting role for LysM peptidoglycan binding domains underpins Enterococcus faecalis daughter cell separation
10.1038/s42003-023-04808-z · 2023 · External reference
A conserved extended signal peptide region directs posttranslational protein translocation via a novel mechanism
10.1099/mic.0.29091-0 · 2007 · External reference
The unusual extended signal peptide region is not required for secretion and function of an Escherichia coli autotransporter
10.1111/j.1574-6968.2010.02081.x · 2010 · External reference
Bacterial size matters: multiple mechanisms controlling septum cleavage and diplococcus formation are critical for the virulence of the opportunistic pathogen Enterococcus faecalis
10.1371/journal.ppat.1006526 · 2017 · External reference
Molecular basis for bacterial peptidoglycan recognition by LysM domains
10.1038/ncomms5269 · 2014 · External reference
Bacterial SPOR domains are recruited to septal peptidoglycan by binding to glycan strands that lack stem peptides
10.1073/pnas.1508536112 · 2015 · External reference
Sur un diplococque saprophyte de l’intestin susceptible de devenir pathogène
1899 · External reference
Decoration of the enterococcal polysaccharide antigen EPA is essential for virulence, cell surface charge and interaction with effectors of the innate immune system
10.1371/journal.ppat.1007730 · 2019 · External reference
Role of class A penicillin-binding proteins in PBP5-mediated beta-lactam resistance in Enterococcus faecalis
10.1128/jb.186.5.1221-1228.2004 · 2004 · External reference
Phosphotransferase systems in Enterococcus faecalis OG1RF enhance anti-stress capacity in vitro and in vivo
10.1016/j.resmic.2017.03.003 · 2017 · External reference
Zebrafish as a novel vertebrate model to dissect enterococcal pathogenesis
10.1128/iai.00976-13 · 2013 · External reference
Generation and testing of mutants of Enterococcus faecalis in a mouse peritonitis model
10.1086/314453 · 1998 · External reference
Dissecting the Enterococcal Polysaccharide Antigen (EPA) structure to explore innate immune evasion and phage specificity
10.1016/j.carbpol.2024.122686 · 2025 · External reference
Complete Structure of the Enterococcal Polysaccharide Antigen (EPA) of Vancomycin-resistant Enterococcus faecalis V583 Reveals that EPA decorations are teichoic acids covalently linked to a rhamnopolysaccharide backbone
10.1128/mbio.00277-20 · 2020 · External reference
The carbohydrate-active enzyme database: functions and literature
10.1093/nar/gkab1045 · 2022 · External reference
Structural basis of cell wall cleavage by a staphylococcal autolysin
10.1371/journal.ppat.1000807 · 2010 · External reference
Impact of peptidoglycan O-acetylation on autolytic activities of the Enterococcus faecalis N-acetylglucosaminidase AtlA and N-acetylmuramidase AtlB
10.1016/j.febslet.2009.08.010 · 2009 · External reference
Fitness restoration of a genetically tractable Enterococcus faecalis V583 derivative to study decoration-related phenotypes of the Enterococcal polysaccharide antigen
10.1128/msphere.00310-19 · 2019 · External reference
Alanine esters of enterococcal lipoteichoic acid play a role in biofilm formation and resistance to antimicrobial peptides
10.1128/iai.00111-06 · 2006 · External reference
Exploring the role of E. faecalis enterococcal polysaccharide antigen (EPA) and lipoproteins in evasion of phagocytosis
10.1111/mmi.15294 · 2024 · External reference
Cleavage specificity of Enterococcus faecalis EnpA (EF1473), a peptidoglycan endopeptidase related to the LytM/lysostaphin family of metallopeptidases
10.1016/j.jmb.2010.03.033 · 2010 · External reference
Processing of the major autolysin of E. faecalis, AtlA, by the zinc-metalloprotease, GelE, impacts AtlA septal localization and cell separation
10.1371/journal.pone.0186706 · 2017 · External reference
The characteristics of autolysins associated with cell separation in Bacillus subtilis
2024 · External reference
The WalRK (YycFG) and σ(I) RsgI regulators cooperate to control CwlO and LytE expression in exponentially growing and stressed Bacillus subtilis cells
10.1111/mmi.12092 · 2013 · External reference
Human skin commensals augment Staphylococcus aureus pathogenesis
10.1038/s41564-018-0198-3 · 2018 · External reference
Bps polysaccharide of Bordetella pertussis resists antimicrobial peptides by functioning as a dual surface shield and decoy and converts Escherichia coli into a respiratory pathogen
10.1371/journal.ppat.1010764 · 2022 · External reference
A novel decoy strategy for polymyxin resistance in Acinetobacter baumannii
10.7554/elife.66988 · 2021 · External reference
Frontline Science: Escherichia coli use LPS as decoy to impair neutrophil chemotaxis and defeat antimicrobial host defense
10.1002/jlb.4hi0319-109r · 2019 · External reference
Site-directed mutagenesis by overlap extension using the polymerase chain reaction
10.1016/0378-1119(89)90358-2 · 1989 · External reference
New thermosensitive plasmid for gram-positive bacteria
10.1128/jb.174.17.5633-5638.1992 · 1992 · External reference
Functional analysis of AtlA, the major N-acetylglucosaminidase of Enterococcus faecalis
10.1128/jb.01145-06 · 2006 · External reference
The overnight express autoinduction system: high-density cell growth and protein expression while you sleep
10.1038/nmeth0305-233 · 2005 · External reference
IQ-TREE 2: new models and efficient methods for phylogenetic inference in the genomic era
10.1093/molbev/msaa015 · 2020 · External reference
Interactive Tree Of Life (iTOL) v4: recent updates and new developments
10.1093/nar/gkz239 · 2019 · External reference
Simple protocol to purify cell wall polysaccharide from gram-positive bacteria and assess its structural integrity
10.1007/978-1-4939-9154-9_4 · 2019 · External reference
Mycobacterium abscessus cording prevents phagocytosis and promotes abscess formation
10.1073/pnas.1321390111 · 2014 · External reference
