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References from Env from EIAV vaccine delicately regulates NLRP3 activation via attenuating NLRP3-NEK7 interaction. Local targets link to admitted publications; unresolved targets remain external evidence.
Equine infectious anemia--a review [Die equine infektiose Anamie-- eine Ubersicht]
2014 · External reference
The role of Cl- and K+ efflux in NLRP3 inflammasome and innate immune response activation
10.1152/ajpcell.00421.2021 · 2022 · External reference
An attenuated EIAV vaccine strain induces significantly different immune responses from its pathogenic parental strain although with similar in vivo replication pattern
10.1016/j.antiviral.2011.08.016 · 2011 · External reference
The pathogenic and vaccine strains of equine infectious anemia virus differentially induce cytokine and chemokine expression and apoptosis in macrophages
10.1016/j.virusres.2011.06.028 · 2011 · External reference
The biology of the HIV-1 latent reservoir and implications for cure strategies
10.1016/j.chom.2020.03.014 · 2020 · External reference
HIV-1 phylogenetics and vaccines
10.1097/coh.0000000000000545 · 2019 · External reference
Latent reservoirs of HIV: obstacles to the eradication of virus
10.1073/pnas.96.20.10958 · 1999 · External reference
Genomic comparison between attenuated Chinese equine infectious anemia virus vaccine strains and their parental virulent strains
10.1007/s00705-010-0877-8 · 2011 · External reference
Equine Infectious Anaemia - a review from an official veterinary perspective [Die Equine Infektiose Anamie - eine Besprechung aus amtstierarztlicher Sicht]
10.17236/sat00232 · 2019 · External reference
Disease investigations for equine infectious anemia in Canada (2009-2012) - Retrospective evaluation and risk factor analysis
2019 · External reference
Equine infectious anemia virus in China
10.18632/oncotarget.20381 · 2017 · External reference
Equine infectious anemia virus in naturally infected horses from the Brazilian Pantanal
10.1007/s00705-018-3877-8 · 2018 · External reference
Genetic Evolution during the development of an attenuated EIAV vaccine
10.1186/s12977-016-0240-6 · 2016 · External reference
Infection with equine infectious anemia virus vaccine strain EIAVDLV121 causes no visible histopathological lesions in target organs in association with restricted viral replication and unique cytokine response
10.1016/j.vetimm.2016.01.006 · 2016 · External reference
Spotlight on the NLRP3 inflammasome pathway
10.2147/jir.s141220 · 2018 · External reference
SARS-CoV-2 viroporin encoded by ORF3a triggers the NLRP3 inflammatory pathway
10.1016/j.virol.2022.01.003 · 2022 · External reference
The P2X7R-NLRP3 and AIM2 inflammasome platforms mark the complexity/severity of viral or metabolic liver damage
10.3390/ijms23137447 · 2022 · External reference
Paxillin mediates ATP-induced activation of P2X7 receptor and NLRP3 inflammasome
10.1186/s12915-020-00918-w · 2020 · External reference
Repurposing drugs targeting the P2X7 receptor to limit hyperinflammation and disease during influenza virus infection
10.1111/bph.14787 · 2019 · External reference
Cutting edge: purinergic signaling regulates radical-mediated bacterial killing mechanisms in macrophages through a P2X7-independent mechanism
10.4049/jimmunol.163.2.558 · 1999 · External reference
Temporal interleukin-1beta secretion from primary human peripheral blood monocytes by P2X7-independent and P2X7-dependent mechanisms
10.1074/jbc.m109.072793 · 2010 · External reference
Env diversity-dependent protection of the attenuated equine infectious anaemia virus vaccine
10.1080/22221751.2020.1773323 · 2020 · External reference
An attenuated EIAV strain and its molecular clone strain differentially induce the expression of Toll-like receptors and type-I interferons in equine monocyte-derived macrophages
10.1016/j.vetmic.2013.06.005 · 2013 · External reference
The P2X7 receptor: A main player in inflammation
10.1016/j.bcp.2017.12.021 · 2018 · External reference
The potential involvement of P2X7 receptor in COVID-19 pathogenesis: A new therapeutic target?
2021 · External reference
Characterization of EIAV env quasispecies during long-term passage in vitro: gradual loss of pathogenicity
10.3390/v11040380 · 2019 · External reference
Amino acid mutations in the env gp90 protein that modify N-linked glycosylation of the Chinese EIAV vaccine strain enhance resistance to neutralizing antibodies
10.1089/vim.2009.0006 · 2010 · External reference
Genomic diversity and antigenic variation of HIV-1: links between pathogenesis, epidemiology and vaccine development
10.1096/fasebj.5.10.2065891 · 1991 · External reference
Polyvalent vaccine approaches to combat HIV-1 diversity
10.1111/imr.12516 · 2017 · External reference
Dynamics of virus-host interplay in HIV-1 replication
10.2174/157016206776055048 · 2006 · External reference
All eyes on the next generation of HIV vaccines: strategies for inducing a broadly neutralizing antibody response
2014 · External reference
Epigenetic regulation of HIV-1 persistence and evolving strategies for virus eradication
10.1007/978-94-007-4525-4_21 · 2013 · External reference
iGLuc: a luciferase-based inflammasome and protease activity reporter
10.1038/nmeth.2327 · 2013 · External reference
The Aedes aegypti mosquito evolves two types of prophenoloxidases with diversified functions
2025 · External reference