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References from Over-expression and increased copy numbers of a cytochrome P450 and two UDP-glucuronosyltransferase genes in macrocyclic lactone resistant Psoroptes ovis of cattle. Local targets link to admitted publications; unresolved targets remain external evidence.
The high cost of sheep scab
10.1136/vr.m3888 · 2020 · External reference
Parasitic mites of medical and veterinary importance–is there a common research agenda?
10.1016/j.ijpara.2014.08.003 · 2014 · External reference
History, biology and control of sheep scab
10.1016/0169-4758(86)90124-9 · 1986 · External reference
The pathology of Psoroptes ovis infestation in cattle with a special emphasis on breed difference
10.1016/s0304-4017(99)00059-x · 1999 · External reference
Genetic and genomic analysis of Belgian Blue’s susceptibility for psoroptic mange
10.1186/s12711-024-00921-7 · 2024 · External reference
Sheep scab: the disease, pathogenesis and control
10.1053/jcpa.2002.0627 · 2003 · External reference
First evidence of resistance to macrocyclic lactones in Psoroptes ovis sheep scab mites in the UK
10.1136/vr.104657 · 2018 · External reference
Comparative evaluation of two ivermectin injectable formulations against psoroptic mange in feedlot cattle
10.1016/j.vetpar.2008.08.007 · 2008 · External reference
Failure of injectable ivermectin to control psoroptic mange in cattle
10.1136/vr.c4906 · 2010 · External reference
Failure of ivermectin efficacy against Psoroptes ovis infestation in cattle: Integrated pharmacokinetic-pharmacodynamic evaluation of two commercial formulations
10.1016/j.vetpar.2018.10.006 · 2018 · External reference
Evaluatie van twee intensieve behandelingsschema’s tegen Psoroptes ovis-schurft bij Belgisch witblauwe runderen op negen Vlaamse rundveebedrijven
2015 · External reference
Multiple resistance to macrocyclic lactones in the sheep scab mite Psoroptes ovis
10.1016/j.vetpar.2019.07.007 · 2019 · External reference
Resistance against macrocyclic lactones in Psoroptes ovis in cattle
10.1186/s13071-020-04008-2 · 2020 · External reference
A review of the molecular mechanisms of acaricide resistance in mites and ticks
10.1016/j.ibmb.2023.103981 · 2023 · External reference
The ABC gene family in arthropods: comparative genomics and role in insecticide transport and resistance
10.1016/j.ibmb.2013.11.001 · 2014 · External reference
Acaricide resistance mechanisms in the two-spotted spider mite Tetranychus urticae and other important Acari: a review
10.1016/j.ibmb.2010.05.008 · 2010 · External reference
New and emerging mechanisms of insecticide resistance
10.1016/j.cois.2024.101184 · 2024 · External reference
High-resolution genetic mapping reveals cis-regulatory and copy number variation in loci associated with cytochrome P450-mediated detoxification in a generalist arthropod pest
10.1371/journal.pgen.1009422 · 2021 · External reference
A nuclear receptor HR96-related gene underlies large trans-driven differences in detoxification gene expression in a generalist herbivore
10.1038/s41467-023-40778-w · 2023 · External reference
Genotype to phenotype, the molecular and physiological dimensions of resistance in arthropods
10.1016/j.pestbp.2015.01.004 · 2015 · External reference
The cys-loop ligand-gated ion channel gene family of Tetranychus urticae: implications for acaricide toxicology and a novel mutation associated with abamectin resistance
10.1016/j.ibmb.2012.03.002 · 2012 · External reference
Glutamate-gated chloride channels
10.1074/jbc.r112.406280 · 2012 · External reference
Evolutionary history of the ligand-gated ion-channel superfamily of receptors
10.1016/0166-2236(95)93887-4 · 1995 · External reference
Molecular mechanisms of Cys-loop ion channel receptor modulation by ivermectin
10.3389/fnmol.2012.00060 · 2012 · External reference
Molecular characterisation of a pH-gated chloride channel from Sarcoptes scabiei
10.1007/s10158-007-0050-6 · 2007 · External reference
A novel chloride channel in Drosophila melanogaster is inhibited by protons
10.1074/jbc.m411759200 · 2005 · External reference
A G326E substitution in the glutamate-gated chloride channel 3 (GluCl3) of the two-spotted spider mite Tetranychus urticae abolishes the agonistic activity of macrocyclic lactones
10.1002/ps.4677 · 2017 · External reference
Dissecting a circuit for olfactory behaviour in Caenorhabditis elegans
10.1038/nature06292 · 2007 · External reference
Mechanosensory inputs influence Caenorhabditis elegans pharyngeal activity via ivermectin sensitivity genes
10.1093/genetics/164.1.153 · 2003 · External reference
Bidirectional regulation of thermotaxis by glutamate transmissions in Caenorhabditis elegans
10.1038/emboj.2011.13 · 2011 · External reference
Recent progress in understanding the interaction between avermectins and ligand-gated ion channels: putting the pests to sleep
10.1007/s10158-010-0105-y · 2010 · External reference
From fruit flies to barnacles, histamine is the neurotransmitter of arthropod photoreceptors
10.1016/s0896-6273(00)80699-6 · 1999 · External reference
Histamine and its receptors modulate temperature-preference behaviors in Drosophila
10.1523/jneurosci.5426-05.2006 · 2006 · External reference
Differential responses to avermectins in ort mutants of Drosophila melanogaster
10.1006/pest.2001.2587 · 2002 · External reference
Altered drug resistance and recovery from paralysis in Drosophila melanogaster with a deficient histamine-gated chloride channel
10.1080/01677060216293 · 2002 · External reference
A UDP-glycosyltransferase gene PcUGT202A9 was associated with abamectin resistance in Panonychus citri (McGregor)
10.1016/j.ijbiomac.2024.132228 · 2024 · External reference
Phenotypic and genotypic plasticity of acaricide resistance in populations of Tetranychus urticae (Acari: Tetranychidae) on peppermint and silage corn in the Pacific Northwest
2018 · External reference
Mechanisms and management of acaricide resistance for Tetranychus urticae in agroecosystems
10.1007/s10340-021-01342-x · 2021 · External reference
Draft genome assembly of the sheep Scab Mite, Psoroptes ovis
2018 · External reference
A genomic analysis and transcriptomic atlas of gene expression in Psoroptes ovis reveals feeding- and stage-specific patterns of allergen expression
10.1186/s12864-019-6082-6 · 2019 · External reference
Unresolved reference
2020 · External reference
MUSCLE: multiple sequence alignment with high accuracy and high throughput
10.1093/nar/gkh340 · 2004 · External reference
Molecular evolutionary genetics analysis (MEGA) for macOS
10.1093/molbev/msz312 · 2020 · External reference
DADA2: High-resolution sample inference from Illumina amplicon data
10.1038/nmeth.3869 · 2016 · External reference
cutPrimers: a new tool for accurate cutting of primers from reads of targeted next generation sequencing
10.1089/cmb.2017.0096 · 2017 · External reference
Assembly of long, error-prone reads using repeat graphs
10.1038/s41587-019-0072-8 · 2019 · External reference
HyPo: super fast & accurate polisher for long read genome assemblies
2019 · External reference
Minimap2: pairwise alignment for nucleotide sequences
2018 · External reference
Unresolved reference
External reference
Automated assembly scaffolding using RagTag elevates a new tomato system for high-throughput genome editing
10.1186/s13059-022-02823-7 · 2022 · External reference
Automated eukaryotic gene structure annotation using EVidenceModeler and the Program to Assemble Spliced Alignments
2008 · External reference
Liftoff: accurate mapping of gene annotations
10.1093/bioinformatics/btaa1016 · 2021 · External reference
Basic local alignment search tool
10.1016/s0022-2836(05)80360-2 · 1990 · External reference
fastp: an ultra-fast all-in-one FASTQ preprocessor
10.1093/bioinformatics/bty560 · 2018 · External reference
Unresolved reference
2010 · External reference
Fast and accurate short read alignment with Burrows-Wheeler transform
10.1093/bioinformatics/btp324 · 2009 · External reference
Unresolved reference
External reference
The Sequence Alignment/Map format and SAMtools
10.1093/bioinformatics/btp352 · 2009 · External reference
VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing
10.1101/gr.129684.111 · 2012 · External reference
A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3
10.4161/fly.19695 · 2012 · External reference
JVarkit: java-based utilities for Bioinformatics
2015 · External reference
Unresolved reference
2019 · External reference
Grenedalf: population genetic statistics for the next generation of pool sequencing
2023 · External reference
PoPoolation2: identifying differentiation between populations using sequencing of pooled DNA samples (Pool-Seq)
10.1093/bioinformatics/btr589 · 2011 · External reference
f-Statistics estimation and admixture graph construction with Pool-Seq or allele count data using the R package poolfstat
10.1111/1755-0998.13557 · 2022 · External reference
pcadapt: an R package to perform genome scans for selection based on principal component analysis
10.1111/1755-0998.12592 · 2017 · External reference
Integrative genomics viewer
10.1038/nbt.1754 · 2011 · External reference
Fast and sensitive protein alignment using DIAMOND
10.1038/nmeth.3176 · 2015 · External reference
Life-cycle stage morphology of Psoroptes mange mites
10.1046/j.1365-2915.2000.00223.x · 2000 · External reference
Near-optimal probabilistic RNA-seq quantification
10.1038/nbt.3519 · 2016 · External reference
RNA-Seq-Pop: Exploiting the sequence in RNA sequencing-A Snakemake workflow reveals patterns of insecticide resistance in the malaria vector Anopheles gambiae
10.1111/1755-0998.13759 · 2023 · External reference
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
10.1186/s13059-014-0550-8 · 2014 · External reference
Differential analysis of RNA-seq incorporating quantification uncertainty
10.1038/nmeth.4324 · 2017 · External reference
Development of a cDNA microarray for the measurement of gene expression in the sheep scab mite Psoroptes ovis
10.1186/1756-3305-5-30 · 2012 · External reference
Allergen expression in the European house dust mite Dermatophagoides pteronyssinus throughout development and response to environmental conditions
10.1111/mve.12102 · 2015 · External reference
Repeated Measures Correlation
10.3389/fpsyg.2017.00456 · 2017 · External reference
The diurnal salivary glands transcriptome of Dermacentor nuttalli from the first four days of blood feeding
10.1016/j.ttbdis.2023.102178 · 2023 · External reference
Sperm structure and phylogeny of Astigmata
10.1002/jmor.10361 · 2005 · External reference
Merqury: reference-free quality, completeness, and phasing assessment for genome assemblies
10.1186/s13059-020-02134-9 · 2020 · External reference
BUSCO: assessing genome assembly and annotation completeness with single-copy orthologs
10.1093/bioinformatics/btv351 · 2015 · External reference
The cys-loop ligand-gated ion channel superfamily of the honeybee, Apis mellifera
10.1007/s10158-006-0026-y · 2006 · External reference
The cys-loop ligand-gated ion channel gene superfamily of the parasitoid wasp, Nasonia vitripennis
10.1038/hdy.2009.97 · 2010 · External reference
High-quality nuclear genome for Sarcoptes scabiei-a critical resource for a neglected parasite
10.1371/journal.pntd.0008720 · 2020 · External reference
Identification of two novel Drosophila melanogaster histamine-gated chloride channel subunits expressed in the eye
10.1074/jbc.m107635200 · 2002 · External reference
The ligand-gated chloride channel gene family of Drosophila melanogaster
10.1016/j.pestbp.2009.09.002 · 2010 · External reference
Characterization of a putative gamma-aminobutyric acid (GABA) receptor beta subunit gene from Drosophila melanogaster
10.1006/bbrc.1993.1648 · 1993 · External reference
Functional significance of aromatic amino acids from three peptide loops of the alpha 7 neuronal nicotinic receptor site investigated by site-directed mutagenesis
10.1016/0014-5793(91)80668-s · 1991 · External reference
Drug-resistant Drosophila indicate glutamate-gated chloride channels are targets for the antiparasitics nodulisporic acid and ivermectin
10.1073/pnas.240464697 · 2000 · External reference
Extensive gene duplication of acetylcholinesterase associated with organophosphate resistance in the two-spotted spider mite
10.1111/j.1365-2583.2009.00958.x · 2010 · External reference
The expression of Spodoptera exigua P450 and UGT genes: tissue specificity and response to insecticides
10.1111/1744-7917.12538 · 2019 · External reference
Overexpression of a cytochrome P450 and a UDP-glycosyltransferase is associated with imidacloprid resistance in the Colorado potato beetle, Leptinotarsa decemlineata
10.1038/s41598-017-01961-4 · 2017 · External reference
Detoxification of ivermectin by ATP binding cassette transporter C4 and cytochrome P450 monooxygenase 6CJ1 in the human body louse, Pediculus humanus humanus
10.1111/imb.12348 · 2018 · External reference
Amplification of a cytochrome P450 gene is associated with resistance to neonicotinoid insecticides in the aphid Myzus persicae
10.1371/journal.pgen.1000999 · 2010 · External reference
Overexpression of UDP-glucuronosyltransferase and cytochrome P450 enzymes confers resistance to sulfoxaflor in field populations of the aphid, Myzus persicae
10.1016/j.ibmb.2022.103743 · 2022 · External reference
Abamectin is metabolized by CYP392A16, a cytochrome P450 associated with high levels of acaricide resistance in Tetranychus urticae
10.1016/j.ibmb.2014.01.006 · 2014 · External reference
Functional analysis of UGT201D3 associated with abamectin resistance in Tetranychus cinnabarinus (Boisduval)
10.1111/1744-7917.12637 · 2020 · External reference
Comparative analysis of the UDP-glycosyltransferase multigene family in insects
10.1016/j.ibmb.2011.11.006 · 2012 · External reference
Bacterial origin of a diverse family of UDP-glycosyltransferase genes in the Tetranychus urticae genome
10.1016/j.ibmb.2014.04.003 · 2014 · External reference
Substrate specificity and promiscuity of horizontally transferred UDP-glycosyltransferases in the generalist herbivore Tetranychus urticae
10.1016/j.ibmb.2019.04.010 · 2019 · External reference
Comparative genomics reveals insights into the divergent evolution of astigmatic mites and household pest adaptations
10.1093/molbev/msac097 · 2022 · External reference
Geographical distribution and molecular insights into abamectin and milbemectin cross-resistance in European field populations of Tetranychus urticae
10.1002/ps.5831 · 2020 · External reference
The UDP-glycosyltransferase (UGT) superfamily expressed in humans, insects and plants: Animal-plant arms-race and co-evolution
10.1016/j.bcp.2015.10.001 · 2016 · External reference
Over-expression in cis of the midgut P450 CYP392A16 contributes to abamectin resistance in Tetranychus urticae
10.1016/j.ibmb.2021.103709 · 2022 · External reference
The effect of insecticide synergists on the response of scabies mites to pyrethroid acaricides
10.1371/journal.pntd.0000354 · 2009 · External reference
Synergistic property of piperonyl butoxide, diethyl maleate, triphenyl phosphate and verapamil hydrochloride with deltamethrin and ivermectin against Rhipicephalus microplus ticks
10.1016/j.ttbdis.2022.102006 · 2022 · External reference
Genome mapping coupled with CRISPR gene editing reveals a P450 gene confers avermectin resistance in the beet armyworm
2021 · External reference
Detoxification mechanisms involved in ivermectin resistance in the cattle tick, Rhipicephalus (Boophilus) microplus
10.1038/s41598-018-30907-7 · 2018 · External reference
Brief exposures of human body lice to sublethal amounts of ivermectin over-transcribes detoxification genes involved in tolerance
10.1111/j.1365-2583.2011.01097.x · 2011 · External reference
Metabolic resistance mechanisms of the housefly (Musca domestica) resistant to pyraclofos
10.1016/j.pestbp.2005.10.005 · 2006 · External reference
Increased transcription of Glutathione S-transferases in acaricide exposed scabies mites
10.1186/1756-3305-3-43 · 2010 · External reference
Functional characterization of glutathione S-transferases associated with insecticide resistance in Tetranychus urticae
10.1016/j.pestbp.2015.01.009 · 2015 · External reference
Does evolutionary theory need a rethink?
10.1038/514161a · 2014 · External reference
Phenotypic plasticity and epigenetic marking: an assessment of evidence for genetic accommodation
10.1111/evo.12348 · 2014 · External reference
A link between host plant adaptation and pesticide resistance in the polyphagous spider mite Tetranychus urticae
10.1073/pnas.1213214110 · 2013 · External reference
Ivermectin acts as a posteclosion nymphicide by reducing blood feeding of human head lice (Anoplura: Pediculidae) that hatched from treated eggs
10.1603/me11051 · 2011 · External reference
Insect GABA receptors: splicing, editing, and targeting by antiparasitics and insecticides
10.1124/mol.105.015313 · 2005 · External reference
High gama-aminobutyric acid contents involved in abamectin resistance and predation, an interesting phenomenon in spider mites
2017 · External reference
Perspectives on gene copy number variation and pesticide resistance
10.1002/ps.6631 · 2022 · External reference
The EccDNA replicon: a heritable, extranuclear vehicle that enables gene amplification and glyphosate resistance in Amaranthus palmeri
10.1105/tpc.20.00099 · 2020 · External reference
Tandem amplification of a chromosomal segment harboring 5-enolpyruvylshikimate-3-phosphate synthase locus confers glyphosate resistance in Kochia scoparia
10.1104/pp.114.242826 · 2014 · External reference
Glyphosate resistance and EPSPS gene duplication: convergent evolution in multiple plant species
10.1093/jhered/esx087 · 2018 · External reference
Subtelomeric transcription and its regulation
10.1016/j.jmb.2020.01.026 · 2020 · External reference
Elevated rates of sister chromatid exchange at chromosome ends
2007 · External reference
Subtelomeric 5-enolpyruvylshikimate-3-phosphate synthase copy number variation confers glyphosate resistance in Eleusine indica
10.1038/s41467-023-40407-6 · 2023 · External reference
Common bean subtelomeres are hot spots of recombination and favor resistance gene evolution
10.3389/fpls.2018.01185 · 2018 · External reference
Transposon accumulation at xenobiotic gene family loci in aphids
10.1101/gr.277820.123 · 2023 · External reference
Transposable elements and xenobiotic resistance
10.3389/finsc.2023.1178212 · 2023 · External reference
Expression of tandem gene duplicates is often greater than twofold
10.1073/pnas.1605886113 · 2016 · External reference
Morphological and molecular comparison of host-derived populations of parasitic Psoroptes mites
10.1111/j.1365-2915.2005.00586.x · 2005 · External reference
A cytochrome P450 allele confers pyrethroid resistance on a major African malaria vector, reducing insecticide-treated bednet efficacy
10.1126/scitranslmed.aat7386 · 2019 · External reference