Research graph
References from Effect of obesity on the acute response to SARS-CoV-2 infection and development of post-acute sequelae of COVID-19 (PASC) in nonhuman primates. Local targets link to admitted publications; unresolved targets remain external evidence.
Post-acute COVID-19 syndrome
10.1038/s41591-021-01283-z · 2021 · External reference
Long-term complications of COVID-19
10.1152/ajpcell.00375.2021 · 2022 · External reference
Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection
10.1001/jama.2023.8823 · 2023 · External reference
Acute and postacute sequelae associated with SARS-CoV-2 reinfection
10.1038/s41591-022-02051-3 · 2022 · External reference
Long COVID science, research and policy
10.1038/s41591-024-03173-6 · 2024 · External reference
Obesity: global epidemiology and pathogenesis
10.1038/s41574-019-0176-8 · 2019 · External reference
Endocrine and metabolic aspects of the COVID-19 pandemic
10.1007/s11154-020-09569-2 · 2020 · External reference
Endocrine and metabolic link to coronavirus infection
10.1038/s41574-020-0353-9 · 2020 · External reference
Risk factors for COVID-19-related mortality in people with type 1 and type 2 diabetes in England: a population-based cohort study
10.1016/s2213-8587(20)30271-0 · 2020 · External reference
COVID-19 and diabetes mellitus: from pathophysiology to clinical management
10.1038/s41574-020-00435-4 · 2021 · External reference
Hyperglycemia without diabetes and new-onset diabetes are both associated with poorer outcomes in COVID-19
10.1016/j.diabres.2020.108382 · 2020 · External reference
COVID-19 and lipids. The role of lipid disorders and statin use in the prognosis of patients with SARS-CoV-2 infection
10.1186/s12944-021-01563-0 · 2021 · External reference
Unresolved reference
2021 · External reference
Individuals with obesity and COVID-19: A global perspective on the epidemiology and biological relationships
10.1111/obr.13128 · 2020 · External reference
Associations between body-mass index and COVID-19 severity in 6·9 million people in England: a prospective, community-based, cohort study
10.1016/s2213-8587(21)00089-9 · 2021 · External reference
The Independent Risk of Obesity and Diabetes and Their Interaction in COVID-19: A Retrospective Cohort Study
10.1002/oby.23172 · 2021 · External reference
Obesity and COVID-19: what makes obese host so vulnerable?
10.1186/s12979-020-00212-x · 2021 · External reference
The association between body mass index class and coronavirus disease 2019 outcomes
10.1038/s41366-020-00721-1 · 2021 · External reference
Association of Obesity With COVID-19 Severity and Mortality: An Updated Systemic Review, Meta-Analysis, and Meta-Regression
10.3389/fendo.2022.780872 · 2022 · External reference
Obesity, respiratory disease and pulmonary infections
10.21037/arh.2017.08.06 · 2017 · External reference
Increased risk of influenza among vaccinated adults who are obese
10.1038/ijo.2017.131 · 2017 · External reference
The impact of obesity on immune response to infection: Plausible mechanisms and outcomes
10.1111/obr.13216 · 2021 · External reference
Impact of obesity on influenza compared to pneumonia hospitalization outcomes
10.1016/j.orcp.2021.03.010 · 2021 · External reference
Obesity and respiratory infections including COVID-19.
10.1007/978-3-031-52696-1_15 · 2024 · External reference
Dysregulation of lipid metabolism and pathological inflammation in patients with COVID-19
10.1038/s41598-021-82426-7 · 2021 · External reference
Risks and burdens of incident dyslipidaemia in long COVID: a cohort study
10.1016/s2213-8587(22)00355-2 · 2023 · External reference
COVID-19, Hyperglycemia, and New-Onset Diabetes
10.2337/dc21-1318 · 2021 · External reference
High-dimensional characterization of post-acute sequelae of COVID-19
10.1038/s41586-021-03553-9 · 2021 · External reference
Newly diagnosed diabetes and diabetic ketoacidosis precipitated by COVID-19 infection
10.1016/j.ajem.2020.05.114 · 2020 · External reference
Proportion of newly diagnosed diabetes in COVID-19 patients: A systematic review and meta-analysis
10.1111/dom.14269 · 2021 · External reference
Diabetic ketoacidosis and COVID-19: what have we learned so far?
2022 · External reference
The Incidence of Diabetes Among 2,777,768 Veterans With and Without Recent SARS-CoV-2 Infection
10.2337/dc21-1686 · 2022 · External reference
Diabetes after SARS-CoV-2 infection
10.1016/s2213-8587(22)00324-2 · 2023 · External reference
Association of COVID-19 Infection With Incident Diabetes
10.1001/jamanetworkopen.2023.8866 · 2023 · External reference
COVID-19 and Diabetes: A Collision and Collusion of Two Diseases
10.2337/dbi20-0032 · 2020 · External reference
Covid-19 and Diabetes: A Complex Bidirectional Relationship
10.3389/fendo.2020.582936 · 2020 · External reference
Coronavirus Infections and Type 2 Diabetes-Shared Pathways with Therapeutic Implications
10.1210/endrev/bnaa011 · 2020 · External reference
Mechanisms and pathophysiology of SARS-CoV-2 infection of the adipose tissue
10.1016/j.tem.2023.08.010 · 2023 · External reference
Hypercoagulopathy and Adipose Tissue Exacerbated Inflammation May Explain Higher Mortality in COVID-19 Patients With Obesity
10.3389/fendo.2020.00530 · 2020 · External reference
Leptin levels in SARS-CoV-2 infection related respiratory failure: A cross-sectional study and a pathophysiological framework on the role of fat tissue
2020 · External reference
Circulating Adiponectin Levels Are Inversely Associated with Mortality and Respiratory Failure in Patients Hospitalized with COVID-19
10.1155/2023/4427873 · 2023 · External reference
Reduced adiponectin levels in patients with COVID-19 acute respiratory failure: A case-control study
10.14814/phy2.14843 · 2021 · External reference
Ghrelin and Leptin Concentrations in Patients after SARS-CoV2 Infection
10.3390/jcm12103551 · 2023 · External reference
Adiponectin, Leptin, and Resistin Are Dysregulated in Patients Infected by SARS-CoV-2
10.3390/ijms24021131 · 2023 · External reference
Adiponectin to leptin ratio reflects inflammatory burden and survival in COVID-19
10.1016/j.diabet.2021.101268 · 2021 · External reference
Discriminatory Value of Adiponectin to Leptin Ratio for COVID-19 Pneumonia
10.1155/2022/9908450 · 2022 · External reference
Adiponectin-leptin Ratio is a Functional Biomarker of Adipose Tissue Inflammation
10.3390/nu11020454 · 2019 · External reference
Decreased adiponectin/leptin ratio relates to insulin resistance in adults with obesity
10.1152/ajpendo.00273.2022 · 2023 · External reference
Hyperglycemia in acute COVID-19 is characterized by insulin resistance and adipose tissue infectivity by SARS-CoV-2
10.1016/j.cmet.2021.09.009 · 2021 · External reference
SARS-CoV-2 infection drives an inflammatory response in human adipose tissue through infection of adipocytes and macrophages
2022 · External reference
Adipose tissue in COVID-19: detection of SARS-CoV-2 in adipocytes and activation of the interferon-alpha response
10.1007/s40618-022-01742-5 · 2022 · External reference
Detection of SARS-CoV-2 in subcutaneous fat but not visceral fat, and the disruption of fat lymphocyte homeostasis in both fat tissues in the macaque
10.1038/s42003-022-03503-9 · 2022 · External reference
Animal models of Long Covid: A hit-and-run disease
10.1126/scitranslmed.ado2104 · 2024 · External reference
Comparison of nonhuman primates identified the suitable model for COVID-19
10.1038/s41392-020-00269-6 · 2020 · External reference
SARS-CoV-2 induces robust germinal center CD4 T follicular helper cell responses in rhesus macaques
10.1038/s41467-020-20642-x · 2021 · External reference
Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets
10.1038/s41564-020-00841-4 · 2021 · External reference
Aerosol delivery of SARS-CoV-2 human monoclonal antibodies in macaques limits viral replication and lung pathology
10.1038/s41467-023-42440-x · 2023 · External reference
Age-related rhesus macaque models of COVID-19
10.1002/ame2.12108 · 2020 · External reference
Virulence and pathogenesis of SARS-CoV-2 infection in rhesus macaques: A nonhuman primate model of COVID-19 progression
10.1371/journal.ppat.1008949 · 2020 · External reference
Mild SARS-CoV-2 infection in rhesus macaques is associated with viral control prior to antigen-specific T cell responses in tissues
2022 · External reference
Respiratory disease in rhesus macaques inoculated with SARS-CoV-2
10.1038/s41586-020-2324-7 · 2020 · External reference
Vascular Disease and Thrombosis in SARS-CoV-2-Infected Rhesus Macaques
2020 · External reference
Obesity in rhesus and cynomolgus macaques: a comparative review of the condition and its implications for research
2011 · External reference
The nonhuman primate as a model for type 2 diabetes
10.1097/med.0000000000000043 · 2014 · External reference
Use and Importance of Nonhuman Primates in Metabolic Disease Research: Current State of the Field
10.1093/ilar/ilx031 · 2017 · External reference
Cynomolgus Macaque Model for COVID-19 Delta Variant
2022 · External reference
Infection and pathogenesis of the Delta variant of SARS-CoV-2 in Rhesus macaque
10.1016/j.virs.2022.02.001 · 2022 · External reference
The kinetics of SARS-CoV-2 infection based on a human challenge study
10.1073/pnas.2406303121 · 2024 · External reference
Sequential Analysis of Binding and Neutralizing Antibody in COVID-19 Convalescent Patients at 14 Months After SARS-CoV-2 Infection
10.3389/fimmu.2021.793953 · 2021 · External reference
Effect of SARS-CoV-2 proteins on vascular permeability
10.7554/elife.69314 · 2021 · External reference
Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor
10.1186/s13578-021-00568-7 · 2021 · External reference
Evolution of antibody immunity to SARS-CoV-2
10.1038/s41586-021-03207-w · 2021 · External reference
Gastrointestinal symptoms and fecal shedding of SARS-CoV-2 RNA suggest prolonged gastrointestinal infection
10.1016/j.medj.2022.04.001 · 2022 · External reference
Multimodal Molecular Imaging Reveals Tissue-Based T Cell Activation and Viral RNA Persistence for Up to 2 Years Following COVID-19
2023 · External reference
SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)
10.1038/s41590-023-01601-2 · 2023 · External reference
The persistence of SARS-CoV-2 in tissues and its association with long COVID symptoms: a cross-sectional cohort study in China
10.1016/s1473-3099(24)00171-3 · 2024 · External reference
Long-Term Persisting SARS-CoV-2 RNA and Pathological Findings: Lessons Learnt From a Series of 35 COVID-19 Autopsies
10.3389/fmed.2022.778489 · 2022 · External reference
COVID-19 Lung Pathogenesis in SARS-CoV-2 Autopsy Cases
10.3389/fimmu.2021.735922 · 2021 · External reference
The Post-Acute Phase of SARS-CoV-2 Infection in Two Macaque Species Is Associated with Signs of Ongoing Virus Replication and Pathology in Pulmonary and Extrapulmonary Tissues
10.3390/v13081673 · 2021 · External reference
Longitudinal analysis of the lung proteome reveals persistent repair months after mild to moderate COVID-19
10.1016/j.xcrm.2024.101642 · 2024 · External reference
Serum NGF and BDNF in Long-COVID-19 Adolescents: A Pilot Study
10.3390/diagnostics12051162 · 2022 · External reference
Immunological profiling in long COVID: overall low grade inflammation and T-lymphocyte senescence and increased monocyte activation correlating with increasing fatigue severity
10.3389/fimmu.2023.1254899 · 2023 · External reference
Persistent immune abnormalities discriminate post-COVID syndrome from convalescence
10.1007/s15010-023-02164-y · 2024 · External reference
Mild respiratory COVID can cause multi-lineage neural cell and myelin dysregulation
10.1016/j.cell.2022.06.008 · 2022 · External reference
Non-human primate model of long-COVID identifies immune associates of hyperglycemia
10.1038/s41467-024-50339-4 · 2024 · External reference
Effect of metabolic status on response to SIV infection and antiretroviral therapy in nonhuman primates
2024 · External reference
Inside out: Bone marrow adipose tissue as a source of circulating adiponectin
10.1080/21623945.2016.1149269 · 2016 · External reference
Adiponectin, the past two decades
10.1093/jmcb/mjw011 · 2016 · External reference
COVID-19 instigates adipose browning and atrophy through VEGF in small mammals
10.1038/s42255-022-00697-4 · 2022 · External reference
Imbalance of Peripheral Temperature, Sympathovagal, and Cytokine Profile in Long COVID
2023 · External reference
Sleep Disturbance Severity and Correlates in Post-acute Sequelae of COVID-19 (PASC)
10.1007/s11606-023-08187-3 · 2023 · External reference
Sleep quality among non-hospitalized COVID-19 survivors: a national cross-sectional study
10.3389/fpubh.2023.1281012 · 2024 · External reference
Systematic Review of the Prevalence of Long COVID
10.1093/ofid/ofad233 · 2023 · External reference
Female gender is associated with long COVID syndrome: a prospective cohort study
2022 · External reference
Sex differences in sequelae from COVID-19 infection and in long COVID syndrome: a review
10.1080/03007995.2022.2081454 · 2022 · External reference
Sex differences and immune correlates of Long Covid development, symptom persistence, and resolution
10.1126/scitranslmed.adr1032 · 2024 · External reference
Non-bronchoscopic Bronchoalveolar Lavage as a Refinement for Safely Obtaining High-quality Samples from Macaques
10.30802/aalas-cm-99-990066 · 2020 · External reference