References

Rickettsia phylogenomics: unwinding the intricacies of obligate intracellular life

10.1371/journal.pone.0002018 · 2008 · External reference

Diagnosis and Management of Tickborne Rickettsial Diseases: Rocky Mountain Spotted Fever and Other Spotted Fever Group Rickettsioses, Ehrlichioses, and Anaplasmosis - United States

10.15585/mmwr.rr6502a1 · 2016 · External reference

Rickettsial genomics and the paradigm of genome reduction associated with increased virulence

10.1016/j.micinf.2017.11.009 · 2018 · External reference

Pathogenicity and virulence of Rickettsia

10.1080/21505594.2022.2132047 · 2022 · External reference

Correlation of the distribution of Rickettsia conorii, microscopic lesions, and clinical features in South African tick bite fever

10.4269/ajtmh.1985.34.361 · 1985 · External reference

The pathology of fatal Mediterranean spotted fever

10.1093/ajcp/87.5.669 · 1987 · External reference

Histopathology and immunohistologic demonstration of the distribution of Rickettsia typhi in fatal murine typhus

10.1093/ajcp/91.6.720 · 1989 · External reference

Severe and Fatal Rocky Mountain Spotted Fever After Exposure in Tecate, Mexico - California, July 2023-January 2024

10.15585/mmwr.mm7347a1 · 2024 · External reference

Spotted Fever Group Rickettsioses in Israel, 2010-2019

10.3201/eid2708.203661 · 2021 · External reference

Immunomodulation by endothelial cells - partnering up with the immune system?

10.1038/s41577-022-00694-4 · 2022 · External reference

Pathogen interactions with endothelial cells and the induction of innate and adaptive immunity

10.1002/eji.201646789 · 2018 · External reference

Rickettsia disrupts and reduces endothelial tight junction protein zonula occludens-1 in association with inflammasome activation

2024 · External reference

Endothelial exosome plays a functional role during rickettsial infection

2021 · External reference

Rickettsia rickettsii virulence determinants RARP2 and RapL mitigate IFN-β signaling in primary human dermal microvascular endothelial cells

10.1128/mbio.03450-23 · 2024 · External reference

Evasion of autophagy mediated by Rickettsia surface protein OmpB is critical for virulence

10.1038/s41564-019-0583-6 · 2019 · External reference

Function and biogenesis of lipopolysaccharides

10.1128/ecosalplus.esp-0001-2018 · 2018 · External reference

Bacterial lipopolysaccharide-induced endothelial activation and dysfunction: a new predictive and therapeutic paradigm for sepsis

10.1186/s40001-023-01301-5 · 2023 · External reference

A cross-disciplinary perspective on the innate immune responses to bacterial lipopolysaccharide

10.1016/j.molcel.2014.03.012 · 2014 · External reference

Innate immunity to intracellular LPS

10.1038/s41590-019-0368-3 · 2019 · External reference

Pushing the envelope: LPS modifications and their consequences

10.1038/s41579-019-0201-x · 2019 · External reference

Orientia and Rickettsia: different flowers from the same garden

10.1016/j.mib.2023.102318 · 2023 · External reference

Wholly Rickettsia! Reconstructed Metabolic Profile of the Quintessential Bacterial Parasite of Eukaryotic Cells

10.1128/mbio.00859-17 · 2017 · External reference

Lipid A Structural Divergence in Rickettsia Pathogens

10.1128/msphere.00184-21 · 2021 · External reference

Structural determination of Rickettsia lipid A without chemical extraction confirms shorter acyl chains in later-evolving spotted fever group pathogens

10.1128/msphere.00609-23 · 2024 · External reference

Rickettsia conorii O antigen is the target of bactericidal Weil-Felix antibodies

10.1073/pnas.1911922116 · 2019 · External reference

Chemical properties of lipopolysaccharides from spotted fever group rickettsiae and their common antigenicity with lipopolysaccharides from Proteus species

10.1128/iai.61.10.4350-4355.1993 · 1993 · External reference

Structural properties of lipopolysaccharides from Rickettsia typhi and Rickettsia prowazekii and their chemical similarity to the lipopolysaccharide from Proteus vulgaris OX19 used in the Weil-Felix test

10.1128/iai.66.3.923-926.1998 · 1998 · External reference

Inflammasome-mediated antagonism of type I interferon enhances Rickettsia pathogenesis

10.1038/s41564-020-0673-5 · 2020 · External reference

Activation of ASC Inflammasome Driven by Toll-Like Receptor 4 Contributes to Host Immunity against Rickettsial Infection

10.1128/iai.00886-19 · 2020 · External reference

Rickettsiae stimulate dendritic cells through toll-like receptor 4, leading to enhanced NK cell activation in vivo

10.1086/595833 · 2009 · External reference

10.1038/s41467-022-31351-y

10.1038/s41467-022-31351-y · 2022 · External reference

Lysine methylation shields an intracellular pathogen from ubiquitylation and autophagy

10.1126/sciadv.abg2517 · 2021 · External reference

Rocky mountain spotted fever: vaccination of monkeys and man

10.2307/4577679 · 1924 · External reference

Immunization of man against epidemic typhus by infection with avirulent Rickettsia prowazeki strain E. IV. Persistence of immunity and a note as to differing complement-fixation antigen requirements in post-infection and post-vaccination sera

10.4049/jimmunol.79.4.348 · 1957 · External reference

Cell-mediated immune responses of adults to vaccination, challenge with Rickettsia rickettsii, or both

10.4269/ajtmh.1992.46.105 · 1992 · External reference

Rickettsia rickettsii Whole-Cell Antigens Offer Protection against Rocky Mountain Spotted Fever in the Canine Host

10.1128/iai.00628-18 · 2019 · External reference

Rocky Mountain spotted fever: a comparative study of the active immunity induced by inactivated and viable pathogenic Rickettsia rickettsii

10.1093/infdis/128.3.340 · 1973 · External reference

Reactogenicity, immunogenicity, and efficacy of a chick embryo cell-derived vaccine for Rocky Mountain spotted fever

10.1093/infdis/148.5.922 · 1983 · External reference

A mutation inactivating the methyltransferase gene in avirulent Madrid E strain of Rickettsia prowazekii reverted to wild type in the virulent revertant strain Evir

10.1016/j.vaccine.2005.11.044 · 2006 · External reference

Emerging and re-emerging rickettsioses: endothelial cell infection and early disease events

10.1038/nrmicro1866 · 2008 · External reference

Pathogenesis of Rickettsial Diseases: Pathogenic and Immune Mechanisms of an Endotheliotropic Infection

10.1146/annurev-pathmechdis-012418-012800 · 2019 · External reference

Evolving functions of endothelial cells in inflammation

10.1038/nri2171 · 2007 · External reference

IL-6 and IL-8 production from cultured human endothelial cells stimulated by infection with Rickettsia conorii via a cell-associated IL-1 alpha-dependent pathway

10.1172/jci118354 · 1995 · External reference

Interleukin-1 alpha production during Rickettsia rickettsii infection of cultured endothelial cells: potential role in autocrine cell stimulation

10.1128/iai.64.5.1609-1613.1996 · 1996 · External reference

Rickettsia rickettsii infection of human macrovascular and microvascular endothelial cells reveals activation of both common and cell type-specific host response mechanisms

10.1128/iai.01335-09 · 2010 · External reference

Expression and secretion of chemotactic cytokines IL-8 and MCP-1 by human endothelial cells after Rickettsia rickettsii infection: regulation by nuclear transcription factor NF-kappaB

10.1016/j.ijmm.2005.05.006 · 2005 · External reference

Relative chemokine and adhesion molecule expression in Mediterranean spotted fever and African tick bite fever

10.1016/j.jinf.2008.11.008 · 2009 · External reference

Rickettsia conorii infection enhances vascular cell adhesion molecule-1- and intercellular adhesion molecule-1-dependent mononuclear cell adherence to endothelial cells

10.1086/520353 · 1997 · External reference

Bacterial lipopolysaccharide activates nuclear factor-kappaB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes

10.1074/jbc.274.12.7611 · 1999 · External reference

The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex

10.1038/nature07830 · 2009 · External reference

Recognition of lipopolysaccharide pattern by TLR4 complexes

2013 · External reference

Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock

10.1126/science.1240988 · 2013 · External reference

Caspase-11-mediated endothelial pyroptosis underlies endotoxemia-induced lung injury

10.1172/jci94495 · 2017 · External reference

Distinct Compartmentalization of the Chemokines CXCL1 and CXCL2 and the Atypical Receptor ACKR1 Determine Discrete Stages of Neutrophil Diapedesis

10.1016/j.immuni.2018.09.018 · 2018 · External reference

Purification and characterization of a novel monocyte chemotactic and activating factor produced by a human myelomonocytic cell line

10.1084/jem.169.4.1485 · 1989 · External reference

Monocyte chemotactic protein-1 regulates voltage-gated K+ channels and macrophage transmigration

10.1007/s11481-008-9135-1 · 2009 · External reference

Chronic inflammation upregulates chemokine receptors and induces neutrophil migration to monocyte chemoattractant protein-1

10.1172/jci5208 · 1999 · External reference

Lymphocyte migration through monolayers of endothelial cell lines involves VCAM-1 signaling via endothelial cell NADPH oxidase

10.4049/jimmunol.164.12.6550 · 2000 · External reference

Leukocyte-endothelial cell interactions are linked to vascular permeability via ICAM-1-mediated signaling

10.1152/ajpheart.00400.2008 · 2008 · External reference

Endothelial cell cortactin coordinates intercellular adhesion molecule-1 clustering and actin cytoskeleton remodeling during polymorphonuclear leukocyte adhesion and transmigration

10.4049/jimmunol.177.9.6440 · 2006 · External reference

Interleukin-1 and Related Cytokines in the Regulation of Inflammation and Immunity

10.1016/j.immuni.2019.03.012 · 2019 · External reference

The role of IL-6 in host defence against infections: immunobiology and clinical implications

10.1038/nrrheum.2017.83 · 2017 · External reference

Interferon-Induced Protein 44 Interacts with Cellular FK506-Binding Protein 5, Negatively Regulates Host Antiviral Responses, and Supports Virus Replication

10.1128/mbio.01839-19 · 2019 · External reference

Interferon-Induced Protein 44 and Interferon-Induced Protein 44-Like Restrict Replication of Respiratory Syncytial Virus

10.1128/jvi.00297-20 · 2020 · External reference

Influenza virus repurposes the antiviral protein IFIT2 to promote translation of viral mRNAs

10.1038/s41564-020-0778-x · 2020 · External reference

The interferon-induced protein, IFIT2, requires RNA-binding activity and neuronal expression to protect mice from intranasal vesicular stomatitis virus infection

10.1128/mbio.00568-24 · 2024 · External reference

IFIT2 is an effector protein of type I IFN-mediated amplification of lipopolysaccharide (LPS)-induced TNF-α secretion and LPS-induced endotoxin shock

10.4049/jimmunol.1203305 · 2013 · External reference

The interferon stimulated gene 54 promotes apoptosis

10.1074/jbc.m110.207068 · 2011 · External reference

NF-kappa B-dependent inhibition of apoptosis is essential for host cellsurvival during Rickettsia rickettsii infection

10.1073/pnas.95.8.4646 · 1998 · External reference

Rickettsia rickettsii infection protects human microvascular endothelial cells against staurosporine-induced apoptosis by a cIAP(2)-independent mechanism

10.1086/597805 · 2009 · External reference

Differences in Intracellular Fate of Two Spotted Fever Group Rickettsia in Macrophage-Like Cells

10.3389/fcimb.2016.00080 · 2016 · External reference

Characteristics of in vitro infection of human monocytes, by Rickettsia helvetica

10.1016/j.micinf.2020.11.003 · 2021 · External reference