References

Candidalysin is a fungal peptide toxin critical for mucosal infection

10.1038/nature17625 · 2016 · External reference

The hyphal-specific toxin candidalysin promotes fungal gut commensalism

10.1038/s41586-024-07142-4 · 2024 · External reference

Candidalysin drives epithelial signaling, neutrophil recruitment, and immunopathology at the vaginal mucosa

10.1128/iai.00645-17 · 2018 · External reference

Candidalysin is required for neutrophil recruitment and virulence during systemic Candida albicans infection

10.1093/infdis/jiz322 · 2019 · External reference

Candidalysin is the hemolytic factor of Candida albicans

10.3390/toxins14120874 · 2022 · External reference

The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes

10.1038/s41467-018-06607-1 · 2018 · External reference

The Candida albicans virulence factor candidalysin polymerizes in solution to form membrane pores and damage epithelial cells

10.7554/elife.75490 · 2022 · External reference

Secretion of the fungal toxin candidalysin is dependent on conserved precursor peptide sequences

10.1038/s41564-024-01606-z · 2024 · External reference

Pore-forming toxins: ancient, but never really out of fashion

10.1038/nrmicro.2015.3 · 2016 · External reference

Sulfated glycosaminoglycans are host epithelial cell targets of the Candida albicans toxin candidalysin

10.1038/s41564-024-01794-8 · 2024 · External reference

Calcium-dependent ESCRT recruitment and lysosome exocytosis maintain epithelial integrity during Candida albicans invasion

10.1016/j.celrep.2021.110187 · 2022 · External reference

Global fungal-host interactome mapping identifies host targets of candidalysin

10.1038/s41467-024-46141-x · 2024 · External reference

Is Candida albicans an opportunistic oncogenic pathogen?

10.1371/journal.ppat.1010413 · 2022 · External reference

Candida albicans stimulates formation of a multi-receptor complex that mediates epithelial cell invasion during oropharyngeal infection

2023 · External reference

CARD9+ microglia promote antifungal immunity via IL-1β- and CXCL1-mediated neutrophil recruitment

10.1038/s41590-019-0377-2 · 2019 · External reference

Toll-like receptor 4 and CD11b expressed on microglia coordinate eradication of Candida albicans cerebral mycosis

10.1016/j.celrep.2023.113240 · 2023 · External reference

Neutrophil extracellular traps capture and kill Candida albicans yeast and hyphal forms

10.1111/j.1462-5822.2005.00659.x · 2006 · External reference

Effect of NLRP3 deficiency on cytotoxic and IL-1β-producing activities of synthetic candidalysin peptide

10.1016/j.job.2023.08.007 · 2023 · External reference

Candidalysin crucially contributes to Nlrp3 inflammasome activation by Candida albicans Hyphae

10.1128/mbio.02221-18 · 2019 · External reference

Candida albicans elicits protective allergic responses via platelet mediated T helper 2 and T helper 17 cell polarization

10.1016/j.immuni.2021.08.009 · 2021 · External reference