Research graph
References from Direct and indirect pathways linking the Lon protease to motility behaviors in the pathogen Pseudomonas aeruginosa. Local targets link to admitted publications; unresolved targets remain external evidence.
Regulated proteolysis in Gram-negative bacteria--how and when?
10.1038/nrmicro2669 · 2011 · External reference
AAA+ proteases: ATP-fueled machines of protein destruction
10.1146/annurev-biochem-060408-172623 · 2011 · External reference
Degrons in protein substrates program the speed and operating efficiency of the AAA+ Lon proteolytic machine
10.1073/pnas.0910392106 · 2009 · External reference
Protein quality control and regulated proteolysis in the genome-reduced organism Mycoplasma pneumoniae
10.15252/msb.20209530 · 2020 · External reference
Regulated Proteolysis in Bacteria: Caulobacter
10.1146/annurev-genet-120215-035235 · 2016 · External reference
ATP-dependent proteases of bacteria: recognition logic and operating principles
10.1016/j.tibs.2006.10.006 · 2006 · External reference
ClpAP is an auxiliary protease for DnaA degradation in Caulobacter crescentus
10.1111/mmi.13537 · 2016 · External reference
Global protein turnover quantification in Escherichia coli reveals cytoplasmic recycling under nitrogen limitation
10.1038/s41467-024-49920-8 · 2024 · External reference
Heat-shock proteases promote survival of Pseudomonas aeruginosa during growth arrest
10.1073/pnas.1912082117 · 2020 · External reference
The Lon AAA+ protease
10.1007/978-94-007-5940-4_2 · 2013 · External reference
ATP hydrolysis-dependent protease activity of the lon (capR) protein of Escherichia coli K-12
10.1073/pnas.78.8.4728 · 1981 · External reference
The product of the lon (capR) gene in Escherichia coli is the ATP-dependent protease, protease La
10.1073/pnas.78.8.4931 · 1981 · External reference
Regulation and quality control by Lon-dependent proteolysis
10.1016/j.resmic.2009.08.021 · 2009 · External reference
Regulation of the general stress response sigma factor σT by Lon-mediated proteolysis
10.1128/jb.00228-23 · 2023 · External reference
An Integrated Proteomic Approach Uncovers Novel Substrates and Functions of the Lon Protease in Escherichia coli
2018 · External reference
RelE, a global inhibitor of translation, is activated during nutritional stress
10.1073/pnas.251327898 · 2001 · External reference
Proteotoxic stress induces a cell-cycle arrest by stimulating Lon to degrade the replication initiator DnaA
10.1016/j.cell.2013.06.034 · 2013 · External reference
Protein degradation in Escherichia coli: the lon gene controls the stability of sulA protein
10.1073/pnas.80.2.358 · 1983 · External reference
Adaptor-mediated Lon proteolysis restricts Bacillus subtilis hyperflagellation
10.1073/pnas.1417419112 · 2015 · External reference
The Lon protease temporally restricts polar cell differentiation events during the Caulobacter cell cycle
10.7554/elife.73875 · 2021 · External reference
Role of lon, an ATP-dependent protease homolog, in resistance of Pseudomonas aeruginosa to ciprofloxacin
10.1128/aac.00830-07 · 2007 · External reference
The Lon protease is essential for full virulence in Pseudomonas aeruginosa
2012 · External reference
Involvement of the lon protease in the SOS response triggered by ciprofloxacin in Pseudomonas aeruginosa PAO1
10.1128/aac.06014-11 · 2012 · External reference
Two Isoforms of Clp Peptidase in Pseudomonas aeruginosa Control Distinct Aspects of Cellular Physiology
2017 · External reference
Two FtsH Proteases Contribute to Fitness and Adaptation of Pseudomonas aeruginosa Clone C Strains
10.3389/fmicb.2019.01372 · 2019 · External reference
The Lon protease of Pseudomonas aeruginosa is induced by aminoglycosides and is involved in biofilm formation and motility
10.1099/mic.0.2006/002519-0 · 2007 · External reference
Pseudomonas aeruginosa: new insights into pathogenesis and host defenses
10.1111/2049-632x.12033 · 2013 · External reference
Federal funding for the study of antimicrobial resistance in nosocomial pathogens: no ESKAPE
10.1086/533452 · 2008 · External reference
Unresolved reference
2024 · External reference
Surface Sensing and Adaptation in Bacteria
10.1146/annurev-micro-012120-063427 · 2020 · External reference
Cross-regulation of Pseudomonas motility systems: the intimate relationship between flagella, pili and virulence
10.1016/j.mib.2015.07.017 · 2015 · External reference
Interconnection of post-transcriptional regulation: The RNA-binding protein Hfq is a novel target of the Lon protease in Pseudomonas aeruginosa
10.1038/srep26811 · 2016 · External reference
Negative regulation of quorum-sensing systems in Pseudomonas aeruginosa by ATP-dependent Lon protease
10.1128/jb.01873-07 · 2008 · External reference
Cellular levels and activity of the flagellar sigma factor FliA of Escherichia coli are controlled by FlgM-modulated proteolysis
10.1111/j.1365-2958.2007.05770.x · 2007 · External reference
Degradation of Lon in Caulobacter crescentus
10.1128/jb.00344-20 · 2020 · External reference
The IbpA and IbpB small heat-shock proteins are substrates of the AAA+ Lon protease
10.1111/j.1365-2958.2010.07070.x · 2010 · External reference
Escherichia coli S-adenosylmethionine decarboxylase. Subunit structure, reductive amination, and NH2-terminal sequences
10.1016/s0021-9258(18)61579-0 · 1987 · External reference
Production of norspermidine contributes to aminoglycoside resistance in pmrAB mutants of Pseudomonas aeruginosa
10.1128/aac.01044-19 · 2019 · External reference
Construction of a mini-Tn5-luxCDABE mutant library in Pseudomonas aeruginosa PAO1: a tool for identifying differentially regulated genes
10.1101/gr.3513905 · 2005 · External reference
Role of sulA and sulB in filamentation by lon mutants of Escherichia coli K-12
10.1128/jb.148.1.265-273.1981 · 1981 · External reference
Inhibition of cell division of Escherichia coli by a new synthetic penicillin, piperacillin
10.1128/aac.14.2.257 · 1978 · External reference
Inactivation of FtsI inhibits constriction of the FtsZ cytokinetic ring and delays the assembly of FtsZ rings at potential division sites
10.1073/pnas.94.2.559 · 1997 · External reference
Penicillin-binding protein 3 sequence variations reduce susceptibility of Pseudomonas aeruginosa to β-lactams but inhibit cell division
10.1093/jac/dkae203 · 2024 · External reference
Characterization of a Pseudomonas aeruginosa gene cluster involved in pilus biosynthesis and twitching motility: sequence similarity to the chemotaxis proteins of enterics and the gliding bacterium Myxococcus xanthus
10.1111/j.1365-2958.1994.tb00296.x · 1994 · External reference
A hierarchical cascade of second messengers regulates Pseudomonas aeruginosa surface behaviors
2015 · External reference
Asymmetric division yields progeny cells with distinct modes of regulating cell cycle-dependent chromosome methylation
10.1073/pnas.1906119116 · 2019 · External reference
The Lon Protease Links Nucleotide Metabolism with Proteotoxic Stress
10.1016/j.molcel.2020.07.011 · 2020 · External reference
Chemotaxis as a navigation strategy to boost range expansion
10.1038/s41586-019-1733-y · 2019 · External reference
Regulation of flagellar motility during biofilm formation
10.1111/1574-6976.12018 · 2013 · External reference
Proteases and their targets in Escherichia coli
10.1146/annurev.genet.30.1.465 · 1996 · External reference
Regulation of SulA cleavage by Lon protease by the C-terminal amino acid of SulA, histidine
10.1042/bj3580473 · 2001 · External reference
Crystal structure of the SOS cell division inhibitor SulA and in complex with FtsZ
10.1073/pnas.1330742100 · 2003 · External reference
Filamentation by Escherichia coli subverts innate defenses during urinary tract infection
10.1073/pnas.0606329104 · 2006 · External reference
Emergence of antibiotic resistance from multinucleated bacterial filaments
10.1073/pnas.1420702111 · 2015 · External reference
DeepVenn -- a web application for the creation of area-proportional Venn diagrams using the deep learning framework Tensorflow.js
2022 · External reference
PANTHER: Making genome-scale phylogenetics accessible to all
10.1002/pro.4218 · 2022 · External reference
Enhanced annotations and features for comparing thousands of Pseudomonas genomes in the Pseudomonas genome database
10.1093/nar/gkv1227 · 2016 · External reference
A versatile bacterial expression vector designed for single-step cloning of multiple DNA fragments using homologous recombination
10.1016/j.pep.2014.03.002 · 2014 · External reference
