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References from Is “pre-sepsis” the new sepsis? A narrative review. Local targets link to admitted publications; unresolved targets remain external evidence.
Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study
10.1016/s0140-6736(19)32989-7 · 2020 · External reference
Hospital-related cost of sepsis: a systematic review
10.1016/j.jinf.2016.11.006 · 2017 · External reference
Why have clinical trials in sepsis failed?
10.1016/j.molmed.2014.01.007 · 2014 · External reference
Unresolved reference
2012 · External reference
Sepsis and septic shock: a history
10.1016/j.ccc.2008.12.003 · 2009 · External reference
Historical perspective of the word “sepsis”
10.1007/s00134-006-0392-2 · 2006 · External reference
The ancient riddle of sigma eta psi iota sigma (sepsis)
1991 · External reference
Harmful molecular mechanisms in sepsis
10.1038/nri2402 · 2008 · External reference
Unresolved reference
External reference
Unresolved reference
1912 · External reference
The host response to sepsis.
10.1007/978-3-540-92276-6_4 · 2009 · External reference
Sepsis: The evolution in definition, pathophysiology, and management
10.1177/2050312119835043 · 2019 · External reference
The immunology of sepsis
10.1016/j.immuni.2021.10.012 · 2021 · External reference
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
10.1378/chest.101.6.1644 · 1992 · External reference
2001 SCCM/ESICM/ACCP/ATS/SIS international sepsis definitions conference
10.1097/01.ccm.0000050454.01978.3b · 2003 · External reference
The epidemiology of sepsis
10.2174/138161208784980590 · 2008 · External reference
The immunopathogenesis of sepsis
10.1038/nature01326 · 2002 · External reference
Sepsis-pathophysiology and therapeutic concepts
10.3389/fmed.2021.628302 · 2021 · External reference
Sepsis: network pathophysiology and implications for early diagnosis
10.1152/ajpregu.00003.2023 · 2023 · External reference
Endothelial barrier dysfunction in septic shock
10.1111/joim.12331 · 2015 · External reference
Endothelial dysfunction and immunothrombosis in sepsis
10.3389/fimmu.2023.1144229 · 2023 · External reference
Thrombosis as an intravascular effector of innate immunity
10.1038/nri3345 · 2013 · External reference
Sepsis-induced immune dysfunction: can immune therapies reduce mortality?
10.1172/jci82224 · 2016 · External reference
Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy
10.1038/nri3552 · 2013 · External reference
Role of the adaptive immune response in sepsis
10.1186/s40635-020-00309-z · 2020 · External reference
The sepsis seesaw: tilting toward immunosuppression
10.1038/nm0509-496 · 2009 · External reference
Multiorgan failure is an adaptive, endocrine-mediated, metabolic response to overwhelming systemic inflammation
10.1016/s0140-6736(04)16815-3 · 2004 · External reference
Severe sepsis and septic shock
10.1056/nejmra1208623 · 2013 · External reference
Clotting dysfunction in sepsis: a role for ros and potential for therapeutic intervention
10.3390/antiox11010088 · 2022 · External reference
Reactive oxygen species interact with NLRP3 inflammasomes and are involved in the inflammation of sepsis: from mechanism to treatment of progression
10.3389/fphys.2020.571810 · 2020 · External reference
Exploring the role of antioxidants in sepsis-associated oxidative stress: a comprehensive review
10.3389/fcimb.2024.1348713 · 2024 · External reference
Role of oxidative stress and mitochondrial dysfunction in sepsis and potential therapies
10.1155/2017/5985209 · 2017 · External reference
Effects of nitric oxide in septic shock
10.1164/ajrccm.161.6.9812004 · 2000 · External reference
Oxidative stress and endothelial dysfunction in sepsis and acute inflammation
10.1089/ars.2021.0027 · 2021 · External reference
The third international consensus definitions for sepsis and septic shock (Sepsis-3)
10.1001/jama.2016.0287 · 2016 · External reference
Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children
10.1097/pcc.0000000000002197 · 2020 · External reference
International consensus criteria for pediatric sepsis and septic shock
10.1001/jama.2024.0179 · 2024 · External reference
The influence of a change in septic shock definitions on intensive care epidemiology and outcome: comparison of sepsis-2 and sepsis-3 definitions
10.1080/23744235.2017.1383630 · 2018 · External reference
Epidemiology of blood culture-proven bacterial sepsis in children in Switzerland: a population-based cohort study
10.1016/s2352-4642(17)30010-x · 2017 · External reference
The global burden of paediatric and neonatal sepsis: a systematic review
10.1016/s2213-2600(18)30063-8 · 2018 · External reference
Early-onset neonatal sepsis
10.1128/cmr.00031-13 · 2014 · External reference
Cytokine profiles as markers of disease severity in sepsis: a multiplex analysis
10.1186/cc5783 · 2007 · External reference
Understanding the inflammatory cytokine response in pneumonia and sepsis: results of the Genetic and Inflammatory Markers of Sepsis (GenIMS) Study
10.1001/archinte.167.15.1655 · 2007 · External reference
Multiplex cytokine profiling in patients with sepsis
10.1111/j.1600-0463.2010.02705.x · 2011 · External reference
Cytokine levels in critically ill children with severe sepsis and their relation with the severity of illness and mortality
10.1177/0885066620912989 · 2021 · External reference
Initial serum level of IL-10 as an outcome predictor in children with sepsis
2018 · External reference
Combination of C-reactive protein, procalcitonin, IL-6, IL-8, and IL-10 for early diagnosis of hyperinflammatory state and organ dysfunction in pediatric sepsis
10.1002/jcla.24505 · 2022 · External reference
Occurrence of marked sepsis-induced immunosuppression in pediatric septic shock: a pilot study
10.1186/s13613-018-0382-x · 2018 · External reference
Pro- versus anti-inflammatory cytokine profile in patients with severe sepsis: a marker for prognosis and future therapeutic options
10.1086/315214 · 2000 · External reference
Comparative assessment of cytokine pattern in early and late onset of neonatal sepsis
10.1155/2017/8601063 · 2017 · External reference
Inflammatory response in preterm and very preterm newborns with sepsis
10.1155/2016/6740827 · 2016 · External reference
Protective immunity and defects in the neonatal and elderly immune response to sepsis
10.4049/jimmunol.1301726 · 2014 · External reference
Increased mortality and altered immunity in neonatal sepsis produced by generalized peritonitis
10.1097/shk.0b013e3180556d09 · 2007 · External reference
Hemodynamic support in fluid-refractory pediatric septic shock
10.1542/peds.102.2.e19 · 1998 · External reference
Quantitated left ventricular systolic mechanics in children with septic shock utilizing noninvasive wall-stress analysis
10.1097/00003246-199422100-00022 · 1994 · External reference
Unique transcriptomic response to sepsis is observed among patients of different age groups
10.1371/journal.pone.0184159 · 2017 · External reference
Immunolocalization of KATP channel subunits in mouse and rat cardiac myocytes and the coronary vasculature
10.1186/1472-6793-5-1 · 2005 · External reference
Developmental changes of intracellular Ca2+ transients in beating rat hearts
10.1152/ajpheart.00308.2003 · 2004 · External reference
The neonatal heart has a relatively high content of total collagen and type I collagen, a condition that may explain the less compliant state
10.1016/0735-1097(94)90612-2 · 1994 · External reference
The host response to sepsis and developmental impact
10.1542/peds.2009-3301 · 2010 · External reference
Sepsis endotypes: the early bird still gets the worm
10.1016/j.ebiom.2022.103832 · 2022 · External reference
Prognostic and predictive enrichment in sepsis
10.1038/s41581-019-0199-3 · 2020 · External reference
Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study
10.1016/s2213-2600(16)00046-1 · 2016 · External reference
Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study
10.1016/s2213-2600(17)30294-1 · 2017 · External reference
A community approach to mortality prediction in sepsis via gene expression analysis
10.1038/s41467-018-03078-2 · 2018 · External reference
Developing a clinically feasible personalized medicine approach to pediatric septic shock
10.1164/rccm.201410-1864oc · 2015 · External reference
Rapid rEcognition of COrticosteRoiD resistant or sensitive Sepsis (RECORDS): study protocol for a multicentre, placebo-controlled, biomarker-guided, adaptive Bayesian design basket trial
10.1136/bmjopen-2022-066496 · 2023 · External reference
Endotype transitions during the acute phase of pediatric septic shock reflect changing risk and treatment response
2018 · External reference
Predicting sepsis severity at first clinical presentation: the role of endotypes and mechanistic signatures
10.1016/j.ebiom.2021.103776 · 2022 · External reference
Identification of subclasses of sepsis that showed different clinical outcomes and responses to amount of fluid resuscitation: a latent profile analysis
10.1186/s13054-018-2279-3 · 2018 · External reference
Identifying novel sepsis subphenotypes using temperature trajectories
10.1164/rccm.201806-1197oc · 2019 · External reference
Gut microbiota and sepsis: from pathogenesis to novel treatments
10.1097/mog.0000000000000781 · 2021 · External reference
Ignoring the elephant: does the infectious diseases society of America support sepsis-3 or pre-sepsis criteria?
10.1093/cid/ciy678 · 2019 · External reference
Pre-sepsis: a necessary concept to complete the SEPSIS-3 picture?
10.1016/j.jcrc.2017.10.041 · 2018 · External reference
Coagulation factor protein abundance in the pre-septic state predicts coagulopathic activities that arise during late-stage murine sepsis
10.1016/j.ebiom.2022.103965 · 2022 · External reference
Time to treatment and mortality during mandated emergency care for sepsis
10.1056/nejmoa1703058 · 2017 · External reference
Association between the New York sepsis care mandate and in-hospital mortality for pediatric sepsis
10.1001/jama.2018.9071 · 2018 · External reference
Sepsis biomarkers and diagnostic tools with a focus on machine learning
10.1016/j.ebiom.2022.104394 · 2022 · External reference
Sepsis biomarkers: advancements and clinical applications-a narrative review
10.3390/ijms25169010 · 2024 · External reference
Profiling the dysregulated immune response in sepsis: overcoming challenges to achieve the goal of precision medicine
10.1016/s2213-2600(23)00330-2 · 2024 · External reference
Point-of-care sensors for the management of sepsis
10.1038/s41551-018-0288-9 · 2018 · External reference
Lipoteichoic acid induces HO-1 expression via the TLR2/MyD88/c-Src/NADPH oxidase pathway and Nrf2 in human tracheal smooth muscle cells
10.4049/jimmunol.181.7.5098 · 2008 · External reference
Carbon monoxide differentially inhibits TLR signaling pathways by regulating ROS-induced trafficking of TLRs to lipid rafts
10.1084/jem.20060845 · 2006 · External reference
Carbon monoxide in sepsis
10.1089/ars.2007.1762 · 2007 · External reference
Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice
10.1038/nm0302-240 · 2002 · External reference
Beneficial effects of the heme oxygenase-1/carbon monoxide system in patients with severe sepsis/septic shock
10.1007/s00134-009-1575-4 · 2010 · External reference
Carbon monoxide concentrations in paediatric sepsis syndrome
10.1136/adc.88.10.889 · 2003 · External reference
Corticosteroid sensitivity detection in sepsis patients using a personalized data mining approach: a clinical investigation
10.1016/j.cmpb.2024.108017 · 2024 · External reference
Surviving septic patients endotyped with a functional assay demonstrate active immune responses
10.3389/fimmu.2024.1418613 · 2024 · External reference
