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References from Splicing-dependent restriction of the HBZ gene by Tax underlies biphasic HTLV-1 infection. Local targets link to admitted publications; unresolved targets remain external evidence.
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10.3390/jcm6120111 · 2017 · External reference
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Hepatitis C viraemia after apparent spontaneous clearance in a vertically infected child
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The KSHV immediate-early transcription factor RTA encodes ubiquitin E3 ligase activity that targets IRF7 for proteosome-mediated degradation
10.1016/j.immuni.2004.11.011 · 2005 · External reference
Kaposi sarcoma-associated herpesvirus latency-associated nuclear antigen: more than a key mediator of viral persistence
10.1016/j.coviro.2023.101336 · 2023 · External reference
Epidemiological Aspects and World Distribution of HTLV-1 Infection
10.3389/fmicb.2012.00388 · 2012 · External reference
Human T-cell leukaemia virus type 1 (HTLV-1) infectivity and cellular transformation
10.1038/nrc2111 · 2007 · External reference
Clinical pathophysiology of human T-lymphotropic virus-type 1-associated myelopathy/tropical spastic paraparesis
10.3389/fmicb.2012.00389 · 2012 · External reference
HTLV-1 persistent infection and ATLL oncogenesis
2023 · External reference
Human T-cell leukemia virus type-1 antisense-encoded gene, Hbz, promotes T-lymphocyte proliferation
10.1182/blood-2008-04-154286 · 2008 · External reference
Enhancement of infectivity and persistence in vivo by HBZ, a natural antisense coded protein of HTLV-1
10.1182/blood-2005-11-4551 · 2006 · External reference
HTLV-1 persistence and the oncogenesis of adult T-cell leukemia/lymphoma
2023 · External reference
HTLV-1: Regulating the Balance Between Proviral Latency and Reactivation
10.3389/fmicb.2018.00449 · 2018 · External reference
HTLV-1 Hbz protein, but not hbz mRNA secondary structure, is critical for viral persistence and disease development
10.1371/journal.ppat.1011459 · 2023 · External reference
Multifaceted functions and roles of HBZ in HTLV-1 pathogenesis
10.1186/s12977-016-0249-x · 2016 · External reference
A novel alternative splicing isoform of human T-cell leukemia virus type 1 bZIP factor (HBZ-SI) targets distinct subnuclear localization
10.1128/jvi.80.5.2495-2505.2006 · 2006 · External reference
HTLV-I antisense transcripts initiating in the 3’LTR are alternatively spliced and polyadenylated
10.1186/1742-4690-3-15 · 2006 · External reference
HTLV-I basic leucine zipper factor gene mRNA supports proliferation of adult T cell leukemia cells
10.1073/pnas.0507631103 · 2006 · External reference
Mechanisms of Oncogenesis by HTLV-1 Tax
10.3390/pathogens9070543 · 2020 · External reference
HTLV-1 bZIP factor enhances TGF-β signaling through p300 coactivator
10.1182/blood-2010-12-326199 · 2011 · External reference
HTLV-1 Tax Tug-of-War: Cellular Senescence and Death or Cellular Transformation
10.3390/pathogens13010087 · 2024 · External reference
HTLV-1 Infection and Adult T-Cell Leukemia/Lymphoma-A Tale of Two Proteins: Tax and HBZ
10.3390/v8060161 · 2016 · External reference
Effects of valproate on Tax and HBZ expression in HTLV-1 and HAM/TSP T lymphocytes
10.1182/blood-2010-11-321364 · 2011 · External reference
KSHV LANA--the master regulator of KSHV latency
10.3390/v6124961 · 2014 · External reference
The complementary strand of the human T-cell leukemia virus type 1 RNA genome encodes a bZIP transcription factor that down-regulates viral transcription
10.1128/jvi.76.24.12813-12822.2002 · 2002 · External reference
Human T-lymphotropic virus type 1 (HTLV-1) and cellular immune response in HTLV-1-associated myelopathy/tropical spastic paraparesis
10.1007/s13365-020-00881-w · 2020 · External reference
RNA splicing factors as oncoproteins and tumour suppressors
10.1038/nrc.2016.51 · 2016 · External reference
Oncogenes and RNA splicing of human tumor viruses
2014 · External reference
MCV and Merkel cell carcinoma: a molecular success story
10.1016/j.coviro.2012.05.007 · 2012 · External reference
Influenza A virus utilizes suboptimal splicing to coordinate the timing of infection
10.1016/j.celrep.2012.12.010 · 2013 · External reference
Human retroviral antisense mRNAs are retained in the nuclei of infected cells for viral persistence
2021 · External reference
Identification and characterization of a novel enhancer in the HTLV-1 proviral genome
10.1038/s41467-022-30029-9 · 2022 · External reference
Targeting the T-Cell Lymphoma Epigenome Induces Cell Death, Cancer Testes Antigens, Immune-Modulatory Signaling Pathways
10.1158/1535-7163.mct-20-0377 · 2021 · External reference
The endogenous HBZ interactome in ATL leukemic cells reveals an unprecedented complexity of host interacting partners involved in RNA splicing
10.3389/fimmu.2022.939863 · 2022 · External reference
HIV-1-encoded antisense RNA suppresses viral replication for a prolonged period
10.1186/1742-4690-9-38 · 2012 · External reference
Transcriptional control of spliced and unspliced human T-cell leukemia virus type 1 bZIP factor (HBZ) gene
10.1128/jvi.00242-08 · 2008 · External reference
Nanopore long-read RNAseq reveals widespread transcriptional variation among the surface receptors of individual B cells
10.1038/ncomms16027 · 2017 · External reference
Human retroviral antisense mRNAs are retained in the nuclei of infected cells for viral persistence
2021 · External reference
Coupling mRNA processing with transcription in time and space
10.1038/nrg3662 · 2014 · External reference
Efficient proximity labeling in living cells and organisms with TurboID
10.1038/nbt.4201 · 2018 · External reference
Creative approaches using proximity labeling to gain new biological insights
10.1016/j.tibs.2023.12.005 · 2024 · External reference
The amino terminus of Tax is required for interaction with the cyclic AMP response element binding protein
10.1128/jvi.69.9.5806-5811.1995 · 1995 · External reference
Control of cAMP-regulated enhancers by the viral transactivator Tax through CREB and the co-activator CBP
10.1038/380642a0 · 1996 · External reference
Intragenic recruitment of NF-κB drives splicing modifications upon activation by the oncogene Tax of HTLV-1
10.1038/s41467-020-16853-x · 2020 · External reference
Human T-cell leukemia virus type 1 Tax shuttles between functionally discrete subcellular targets
10.1128/jvi.74.5.2351-2364.2000 · 2000 · External reference
A subcellular map of the human proteome
2017 · External reference
β-Actin mRNA interactome mapping by proximity biotinylation
10.1073/pnas.1820737116 · 2019 · External reference
Coupling of spliceosome complexity to intron diversity
10.1016/j.cub.2021.09.004 · 2021 · External reference
Cis-perturbation of cancer drivers by the HTLV-1/BLV proviruses is an early determinant of leukemogenesis
10.1038/ncomms15264 · 2017 · External reference
Molecular Mechanisms of Merkel Cell Polyomavirus Transformation and Replication
10.1146/annurev-virology-011720-121757 · 2020 · External reference
5’-long terminal repeat-selective CpG methylation of latent human T-cell leukemia virus type 1 provirus in vitro and in vivo
10.1128/jvi.76.18.9389-9397.2002 · 2002 · External reference
HTLV-1 modulates the frequency and phenotype of FoxP3+CD4+ T cells in virus-infected individuals
10.1186/1742-4690-9-46 · 2012 · External reference
Primary cells from patients with adult T cell leukemia/lymphoma depend on HTLV-1 Tax expression for NF-κB activation and survival
10.1038/s41408-023-00841-7 · 2023 · External reference
Sporadic on/off switching of HTLV-1 Tax expression is crucial to maintain the whole population of virus-induced leukemic cells
10.1073/pnas.1715724115 · 2018 · External reference
Intragenic recruitment of NF-κB drives splicing modifications upon activation by the oncogene Tax of HTLV-1
10.1038/s41467-020-16853-x · 2020 · External reference
The HTLV-1 viral oncoproteins Tax and HBZ reprogram the cellular mRNA splicing landscape
10.1371/journal.ppat.1009919 · 2021 · External reference
The single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction: twenty-something years on
10.1038/nprot.2006.83 · 2006 · External reference
RIP: RNA Immunoprecipitation
10.1007/978-1-4939-6380-5_7 · 2016 · External reference
New strategies to improve minimap2 alignment accuracy
10.1093/bioinformatics/btab705 · 2021 · External reference
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10.1093/bioinformatics/bts635 · 2013 · External reference
Twelve years of SAMtools and BCFtools
10.1093/gigascience/giab008 · 2021 · External reference
Full-length transcript characterization of SF3B1 mutation in chronic lymphocytic leukemia reveals downregulation of retained introns
10.1038/s41467-020-15171-6 · 2020 · External reference
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10.1038/nbt.1754 · 2011 · External reference
Analysing high-throughput sequencing data in Python with HTSeq 2.0
10.1093/bioinformatics/btac166 · 2022 · External reference
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
10.1186/s13059-014-0550-8 · 2014 · External reference
featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
10.1093/bioinformatics/btt656 · 2014 · External reference
RSeQC: quality control of RNA-seq experiments
10.1093/bioinformatics/bts356 · 2012 · External reference
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2021 · External reference
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KEGG: biological systems database as a model of the real world
2024 · External reference
MAFFT-DASH: integrated protein sequence and structural alignment
2019 · External reference