Research graph
References from Multivalent mpox protein nanoparticle vaccines confer cross-protection against orthopoxvirus infection. Local targets link to admitted publications; unresolved targets remain external evidence.
Phylogenomic analysis of the monkeypox virus (MPXV) 2022 outbreak: Emergence of a novel viral lineage?
10.1016/j.tmaid.2022.102402 · 2022 · External reference
Clinical features and viral load variations of Mpox: a retrospective study in Chongqing, China
10.1186/s12879-024-09537-0 · 2024 · External reference
Monkeypox
10.1056/nejmra2208860 · 2022 · External reference
Monkeypox Virus Infection in Humans across 16 Countries - April-June 2022
10.1056/nejmoa2207323 · 2022 · External reference
Unresolved reference
External reference
The WHO Declaration of Monkeypox as a Global Public Health Emergency
10.1001/jama.2022.12513 · 2022 · External reference
Unresolved reference
External reference
Unresolved reference
External reference
Unresolved reference
External reference
Growing mpox outbreak prompts WHO to declare global health emergency
2024 · External reference
Sustained human outbreak of a new MPXV clade I lineage in eastern Democratic Republic of the Congo
2024 · External reference
Unresolved reference
External reference
Analysis of the monkeypox virus genome
10.1006/viro.2002.1446 · 2002 · External reference
Genomic variability of monkeypox virus among humans, Democratic Republic of the Congo
10.3201/eid2002.130118 · 2014 · External reference
Unresolved reference
1988 · External reference
Unresolved reference
External reference
Immunogenicity and safety of three consecutive production lots of the non replicating smallpox vaccine MVA: A randomised, double blind, placebo controlled phase III trial
10.1371/journal.pone.0195897 · 2018 · External reference
A randomized phase 3 trial to assess the immunogenicity and safety of 3 consecutively produced lots of freeze-dried MVA-BN® vaccine in healthy adults
10.1016/j.vaccine.2022.10.056 · 2023 · External reference
Unresolved reference
External reference
Low levels of monkeypox virus-neutralizing antibodies after MVA-BN vaccination in healthy individuals
10.1038/s41591-022-02090-w · 2023 · External reference
Vaccine Effectiveness of JYNNEOS against Mpox Disease in the United States
10.1056/nejmoa2215201 · 2023 · External reference
An open-label, non-randomized study investigating the safety and efficacy of smallpox vaccine, LC16, as post-exposure prophylaxis for mpox
10.1080/21645515.2023.2242219 · 2023 · External reference
Monkeypox (Mpox) vaccines and their side effects: the other side of the coin
10.1097/js9.0000000000000142 · 2023 · External reference
Vaccine effectiveness of 3rd generation mpox vaccines against mpox and disease severity: A systematic review and meta-analysis
10.1016/j.vaccine.2024.06.021 · 2024 · External reference
Orthopoxvirus species and strain differences in cell entry
10.1016/j.virol.2012.08.044 · 2012 · External reference
The land-scape of immune response to monkeypox virus
10.1016/j.ebiom.2022.104424 · 2023 · External reference
Smallpox vaccines: targets of protective immunity
10.1111/j.1600-065x.2010.00975.x · 2011 · External reference
Polyclonal antibody cocktails generated using DNA vaccine technology protect in murine models of orthopoxvirus disease
10.1186/1743-422x-8-441 · 2011 · External reference
Comprehensive literature review of monkeypox
10.1080/22221751.2022.2132882 · 2022 · External reference
Exploring monkeypox virus proteins and rapid detection techniques
10.3389/fcimb.2024.1414224 · 2024 · External reference
Four-gene-combination DNA vaccine protects mice against a lethal vaccinia virus challenge and elicits appropriate antibody responses in nonhuman primates
10.1016/s0042-6822(02)00038-7 · 2003 · External reference
Cross-Neutralizing and Protective Human Antibody Specificities to Poxvirus Infections
10.1016/j.cell.2016.09.049 · 2016 · External reference
Smallpox DNA vaccine protects nonhuman primates against lethal monkeypox
10.1128/jvi.78.9.4433-4443.2004 · 2004 · External reference
A Nucleic Acid-Based Orthopoxvirus Vaccine Targeting the Vaccinia Virus L1, A27, B5, and A33 Proteins Protects Rabbits against Lethal Rabbitpox Virus Aerosol Challenge
10.1128/jvi.01504-21 · 2022 · External reference
mRNA vaccines encoding fusion proteins of monkeypox virus antigens protect mice from vaccinia virus challenge
10.1038/s41467-023-41628-5 · 2023 · External reference
Synergistic effect of two human-like monoclonal antibodies confers protection against orthopoxvirus infection
10.1038/s41467-024-47328-y · 2024 · External reference
Nanoparticle-Based Vaccines Against Respiratory Viruses
10.3389/fimmu.2019.00022 · 2019 · External reference
A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates
10.1126/scitranslmed.abi5735 · 2022 · External reference
Quadrivalent influenza nanoparticle vaccines induce broad protection
10.1038/s41586-021-03365-x · 2021 · External reference
Dual-targeting nanoparticle vaccine elicits a therapeutic antibody response against chronic hepatitis B
10.1038/s41565-020-0648-y · 2020 · External reference
Mosaic RBD nanoparticles protect against challenge by diverse sarbecoviruses in animal models
10.1126/science.abq0839 · 2022 · External reference
Mosaic RBD nanoparticle elicits immunodominant antibody responses across sarbecoviruses
10.1016/j.celrep.2024.114235 · 2024 · External reference
Peptide tag forming a rapid covalent bond to a protein, through engineering a bacterial adhesin
10.1073/pnas.1115485109 · 2012 · External reference
Cross-reactive immune responses to monkeypox virus induced by MVA vaccination in mice
10.1186/s12985-023-02085-0 · 2023 · External reference
Polyvalent mRNA vaccination elicited potent immune response to monkeypox virus surface antigens
10.1038/s41422-023-00792-5 · 2023 · External reference
Rational design of a “two-in-one” immunogen DAM drives potent immune response against mpox virus
10.1038/s41590-023-01715-7 · 2024 · External reference
Time is now: Preparing for the next pandemic
10.1016/j.hlife.2024.12.008 · 2025 · External reference
Global public health crisis response: A roundtable discussion with Professor George Fu Gao, Professor Jules A Hoffmann, Professor Chris Walzer and Professor Jiahai Lu
10.1016/j.hlife.2023.10.001 · 2023 · External reference
Viral targets for vaccines against COVID-19
10.1038/s41577-020-00480-0 · 2021 · External reference
A protective human antibody against respiratory syncytial virus by targeting a prefusion epitope across sites IV and V of the viral fusion glycoprotein
10.1016/j.hlife.2023.09.003 · 2023 · External reference
Mosaic nanoparticles elicit cross-reactive immune responses to zoonotic coronaviruses in mice
10.1126/science.abf6840 · 2021 · External reference
Rapid and highly potent humoral responses to mpox nanovaccine candidates adjuvanted by thermostable scaffolds
10.1016/j.vaccine.2024.02.027 · 2024 · External reference
Protein Nanoparticle-Mediated Delivery of Recombinant Influenza Hemagglutinin Enhances Immunogenicity and Breadth of the Antibody Response
10.1021/acsinfecdis.2c00362 · 2023 · External reference
Precursor Frequency and Affinity Determine B Cell Competitive Fitness in Germinal Centers, Tested with Germline-Targeting HIV Vaccine Immunogens
10.1016/j.immuni.2017.11.023 · 2018 · External reference
Vaccine delivery: a matter of size, geometry, kinetics and molecular patterns
10.1038/nri2868 · 2010 · External reference
Induction of Potent Neutralizing Antibody Responses by a Designed Protein Nanoparticle Vaccine for Respiratory Syncytial Virus
10.1016/j.cell.2019.01.046 · 2019 · External reference
Programming the magnitude and persistence of antibody responses with innate immunity
10.1038/nature09737 · 2011 · External reference
Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination
2016 · External reference
Dendritic cell subsets in T cell programming: location dictates function
10.1038/s41577-018-0088-1 · 2019 · External reference
A multivalent mRNA monkeypox virus vaccine (BNT166) protects mice and macaques from orthopoxvirus disease
10.1016/j.cell.2024.01.017 · 2024 · External reference
Monkeypox virus-infected individuals mount comparable humoral immune responses as smallpox-vaccinated individuals
10.1038/s41467-023-41587-x · 2023 · External reference
Polyvalent mpox mRNA vaccines elicit robust immune responses and confer potent protection against vaccinia virus
10.1016/j.celrep.2024.114269 · 2024 · External reference
Human antibody responses to circulating monkeypox virus emphasise the need for the first mpox-specific vaccine
10.1016/s2666-5247(23)00365-8 · 2024 · External reference
An mpox virus mRNA-lipid nanoparticle vaccine confers protection against lethal orthopoxviral challenge
10.1126/scitranslmed.adg3540 · 2023 · External reference
Vaccination of BALB/c mice with Escherichia coli-expressed vaccinia virus proteins A27L, B5R, and D8L protects mice from lethal vaccinia virus challenge
10.1128/jvi.01854-07 · 2008 · External reference
A myristylated membrane protein encoded by the vaccinia virus L1R open reading frame is the target of potent neutralizing monoclonal antibodies
10.1006/viro.1995.1378 · 1995 · External reference
Vaccinia virus extracellular enveloped virion neutralization in vitro and protection in vivo depend on complement
10.1128/jvi.01797-08 · 2009 · External reference
Immunogenicity and protection efficacy of monovalent and polyvalent poxvirus vaccines that include the D8 antigen
10.1016/j.virol.2006.07.017 · 2006 · External reference
Combinations of polyclonal or monoclonal antibodies to proteins of the outer membranes of the two infectious forms of vaccinia virus protect mice against a lethal respiratory challenge
10.1128/jvi.79.21.13454-13462.2005 · 2005 · External reference
Multi-valent mRNA vaccines against monkeypox enveloped or mature viron surface antigens demonstrate robust immune response and neutralizing activity
10.1007/s11427-023-2378-x · 2023 · External reference
Comparison of protection against mpox following mRNA or modified vaccinia Ankara vaccination in nonhuman primates
10.1016/j.cell.2024.08.043 · 2024 · External reference
Two noncompeting human neutralizing antibodies targeting MPXV B6 show protective effects against orthopoxvirus infections
10.1038/s41467-024-48312-2 · 2024 · External reference
Vaccination induces HIV broadly neutralizing antibody precursors in humans
10.1126/science.add6502 · 2022 · External reference
Preparation of Cell Cultures and Vaccinia Virus Stocks
10.1002/cpps.34 · 2017 · External reference
