Research graph
References from Screening of different species reveals cat hepatocytes support HBV infection. Local targets link to admitted publications; unresolved targets remain external evidence.
New WHO guidance for country validation of viral hepatitis B and C elimination
10.1016/s2468-1253(21)00267-3 · 2021 · External reference
Development of Direct-acting Antiviral and Host-targeting Agents for Treatment of Hepatitis B Virus Infection
10.1053/j.gastro.2018.07.057 · 2019 · External reference
Current treatment guidelines of chronic hepatitis B: The role of nucleos(t)ide analogues and peginterferon
10.1016/j.bpg.2017.04.012 · 2017 · External reference
Prevention of hepatitis B virus-related hepatocellular carcinoma
2004 · External reference
Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus
2012 · External reference
Hepatitis B virus cccDNA: Formation, regulation and therapeutic potential
10.1016/j.antiviral.2020.104824 · 2020 · External reference
Nucleolin binds to and regulates transcription of hepatitis B virus covalently closed circular DNA minichromosome
2023 · External reference
Novel function of SART1 in HNF4α transcriptional regulation contributes to its antiviral role during HBV infection
10.1016/j.jhep.2021.06.038 · 2021 · External reference
G-quadruplex in hepatitis B virus pregenomic RNA promotes its translation
10.1016/j.jbc.2023.105151 · 2023 · External reference
Hepatitis B virus RNAs co-opt ELAVL1 for stabilization and CRM1-dependent nuclear export
10.1371/journal.ppat.1011999 · 2024 · External reference
Hepatitis B virus hijacks TSG101 to facilitate egress via multiple vesicle bodies
10.1371/journal.ppat.1011382 · 2023 · External reference
The size of the viral inoculum contributes to the outcome of hepatitis B virus infection
10.1128/jvi.00867-09 · 2009 · External reference
Hepatitis B virus infection of tupaia hepatocytes in vitro and in vivo
10.1002/hep.510240101 · 1996 · External reference
Co-delivery of Cas9 mRNA and guide RNAs edits hepatitis B virus episomal and integration DNA in mouse and tree shrew models
10.1016/j.antiviral.2023.105618 · 2023 · External reference
Hepatocytic expression of human sodium-taurocholate cotransporting polypeptide enables hepatitis B virus infection of macaques
10.1038/s41467-017-01953-y · 2017 · External reference
Long-term hepatitis B virus infection of rhesus macaques requires suppression of host immunity
10.1038/s41467-022-30593-0 · 2022 · External reference
Liver-specific transgenic expression of human NTCP in rhesus macaques confers HBV susceptibility on primary hepatocytes
2025 · External reference
Limited disassembly of cytoplasmic hepatitis B virus nucleocapsids restricts viral infection in murine hepatic cells
10.1002/hep.32622 · 2023 · External reference
Evidence that hepatitis B virus replication in mouse cells is limited by the lack of a host cell dependency factor
10.1016/j.jhep.2015.10.030 · 2016 · External reference
Efficient inhibition of hepatitis B virus infection by acylated peptides derived from the large viral surface protein
10.1128/jvi.79.3.1613-1622.2005 · 2005 · External reference
Characterisation of the hepatitis B virus cross-species transmission pattern via Na+/taurocholate co-transporting polypeptides from 11 New World and Old World primate species
10.1371/journal.pone.0199200 · 2018 · External reference
Sodium taurocholate cotransporting polypeptide is the limiting host factor of hepatitis B virus infection in macaque and pig hepatocytes
10.1002/hep.29112 · 2017 · External reference
Core components of DNA lagging strand synthesis machinery are essential for hepatitis B virus cccDNA formation
10.1038/s41564-020-0678-0 · 2020 · External reference
Hepatitis B virus hijacks MRE11–RAD50–NBS1 complex to form its minichromosome
2025 · External reference
Entecavir: A Review and Considerations for Its Application in Oncology
10.3390/ph16111603 · 2023 · External reference
Human stem cell-derived hepatocytes as a model for hepatitis B virus infection, spreading and virus-host interactions
2016 · External reference
Poly I:C-based rHBVvac therapeutic vaccine eliminates HBV via generation of HBV-specific CD8+ effector memory T cells
10.1136/gutjnl-2017-315588 · 2019 · External reference
Molecular determinants of hepatitis B and D virus entry restriction in mouse sodium taurocholate cotransporting polypeptide
10.1128/jvi.03540-12 · 2013 · External reference
Repopulation of mouse liver with human hepatocytes and in vivo infection with hepatitis B virus
10.1053/jhep.2001.23314 · 2001 · External reference
A novel hepatitis B virus species discovered in capuchin monkeys sheds new light on the evolution of primate hepadnaviruses
10.1016/j.jhep.2018.01.029 · 2018 · External reference
Targeted viral adaptation generates a simian-tropic hepatitis B virus that infects marmoset cells
10.1038/s41467-023-39148-3 · 2023 · External reference
A virus similar to human hepatitis B virus associated with hepatitis and hepatoma in woodchucks
10.1073/pnas.75.9.4533 · 1978 · External reference
Virus of Pekin ducks with structural and biological relatedness to human hepatitis B virus
10.1128/jvi.36.3.829-836.1980 · 1980 · External reference
Identification of NTCP animal orthologs supporting hepatitis B virus binding and infection
10.1128/jvi.01833-24 · 2025 · External reference
The feasibility of establishing a hamster model for HBV infection: in vitro evidence
10.1128/mbio.02615-24 · 2024 · External reference
Viral entry of hepatitis B and D viruses and bile salts transportation share common molecular determinants on sodium taurocholate cotransporting polypeptide
10.1128/jvi.03478-13 · 2014 · External reference
Hepatitis B and D viruses exploit sodium taurocholate co-transporting polypeptide for species-specific entry into hepatocytes
10.1053/j.gastro.2013.12.024 · 2014 · External reference
Structural basis of hepatitis B virus receptor binding
10.1038/s41594-023-01191-5 · 2024 · External reference
Identification of amino acids restricting HBV receptor function in porcine NTCP
10.1038/s44298-024-00041-5 · 2024 · External reference
A Single Adaptive Mutation in Sodium Taurocholate Cotransporting Polypeptide Induced by Hepadnaviruses Determines Virus Species Specificity
10.1128/jvi.01432-18 · 2019 · External reference
Structural basis for hepatitis B virus restriction by a viral receptor homologue
10.1038/s41467-024-53533-6 · 2024 · External reference
A Novel Hepadnavirus Identified in an Immunocompromised Domestic Cat in Australia
10.3390/v10050269 · 2018 · External reference
Identification of hepadnavirus in the sera of cats
10.1038/s41598-019-47175-8 · 2019 · External reference
Insights into the genetic diversity, recombination, and systemic infections with evidence of intracellular maturation of hepadnavirus in cats
10.1371/journal.pone.0241212 · 2020 · External reference
Prevalence and Genomic Sequence Analysis of Domestic Cat Hepadnavirus in the United States
10.3390/v14102091 · 2022 · External reference
Conserved use of the sodium/bile acid cotransporter (NTCP) as an entry receptor by hepatitis B virus and domestic cat hepadnavirus
10.1016/j.antiviral.2023.105695 · 2023 · External reference
Suspected Cat-to-Human Transmission of SARS-CoV-2, Thailand, July-September 2021
10.3201/eid2807.212605 · 2022 · External reference
Adenovirus Isolated From a Cat Is Related to Human Adenovirus 1
10.3389/fmicb.2019.01430 · 2019 · External reference
Hepatitis B
10.1016/s0140-6736(22)01468-4 · 2023 · External reference
Immunobiology and pathogenesis of hepatitis B virus infection
10.1038/s41577-021-00549-4 · 2022 · External reference
Domestic cats as laboratory animals
2002 · External reference
Role of animal models in biomedical research: a review
10.1186/s42826-022-00128-1 · 2022 · External reference
Animal models for COVID-19
10.1038/s41586-020-2787-6 · 2020 · External reference
Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA
10.1126/science.1243462 · 2014 · External reference
Assembly of hepatitis delta virus: particle characterization, including the ability to infect primary human hepatocytes
10.1128/jvi.02277-06 · 2007 · External reference
A Novel Mouse Model Harboring Hepatitis B Virus Covalently Closed Circular DNA
10.1016/j.jcmgh.2021.11.011 · 2022 · External reference
Coexistence of hepatitis B virus quasispecies enhances viral replication and the ability to induce host antibody and cellular immune responses
10.1128/jvi.01123-14 · 2014 · External reference