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References from Pattern recognition receptor-associated immuno-thrombotic transcript changes in platelets and leukocytes with COVID19. Local targets link to admitted publications; unresolved targets remain external evidence.
Platelets and SARS-CoV-2 during COVID-19: immunity, thrombosis, and beyond
10.1161/circresaha.122.321930 · 2023 · External reference
Acute Myocardial Infarction after Laboratory-Confirmed Influenza Infection
10.1056/nejmoa1702090 · 2018 · External reference
Thromboembolism in Mycobacterium tuberculosis Infection: Analysis and Literature Review
10.3947/ic.2019.51.2.142 · 2019 · External reference
Sex differences in platelet toll-like receptors and their association with cardiovascular risk factors
10.1161/atvbaha.114.304954 · 2015 · External reference
The role of RNA uptake in platelet heterogeneity
10.1160/th16-11-0873 · 2017 · External reference
Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome
10.1182/blood.2020007008 · 2020 · External reference
Platelet and Megakaryocyte Roles in Innate and Adaptive Immunity
10.1161/circresaha.121.319821 · 2022 · External reference
Regulation of cGAS- and RLR-mediated immunity to nucleic acids
10.1038/s41590-019-0556-1 · 2020 · External reference
TLR3 and TLR7 RNA Sensor Activation during SARS-CoV-2 Infection
10.3390/microorganisms9091820 · 2021 · External reference
Distinct SARS-CoV-2 RNA fragments activate Toll-like receptors 7 and 8 and induce cytokine release from human macrophages and microglia
2023 · External reference
MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells
10.1016/j.celrep.2020.108628 · 2021 · External reference
RIG-I in RNA virus recognition
10.1016/j.virol.2015.02.017 · 2015 · External reference
RIG-I triggers a signaling-abortive anti-SARS-CoV-2 defense in human lung cells
10.1038/s41590-021-00942-0 · 2021 · External reference
The role of inflammation in regulating platelet production and function: Toll-like receptors in platelets and megakaryocytes
10.1016/j.thromres.2009.11.004 · 2010 · External reference
SARS-CoV-2 Initiates Programmed Cell Death in Platelets
10.1161/circresaha.121.319117 · 2021 · External reference
Necroptosis, pyroptosis, ferroptosis in sepsis and treatment
10.1097/shk.0000000000001936 · 2022 · External reference
Human Platelets and Influenza Virus: Internalization and Platelet Activation
10.1080/09537104.2021.1961710 · 2022 · External reference
Global epidemiology of venous thromboembolism in people with active tuberculosis: a systematic review and meta-analysis
10.1007/s11239-020-02211-7 · 2021 · External reference
Genome-wide RNA-seq analysis of human and mouse platelet transcriptomes
10.1182/blood-2011-03-339705 · 2011 · External reference
Relation of platelet and leukocyte inflammatory transcripts to body mass index in the Framingham heart study
10.1161/circulationaha.109.928192 · 2010 · External reference
Toll-Like Receptor 4-Dependent Platelet-Related Thrombosis in SARS-CoV-2 Infection
10.1161/circresaha.122.321541 · 2023 · External reference
ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection
10.1126/sciimmunol.abo6294 · 2022 · External reference
Platelet proteome reveals features of cell death, antiviral response and viral replication in covid-19
10.1038/s41420-022-01122-1 · 2022 · External reference
Association of COVID-19 With Major Arterial and Venous Thrombotic Diseases: A Population-Wide Cohort Study of 48 Million Adults in England and Wales
10.1161/circulationaha.122.060785 · 2022 · External reference
Acute Myocardial Infarction after Laboratory-Confirmed Influenza Infection
10.1056/nejmoa1702090 · 2018 · External reference
The RNA sensor MDA5 detects SARS-CoV-2 infection
10.1038/s41598-021-92940-3 · 2021 · External reference
Platelet GPVI (Glycoprotein VI) and Thrombotic Complications in the Venous System
10.1161/atvbaha.121.316108 · 2021 · External reference
Platelet gene expression and function in patients with COVID-19
10.1182/blood.2020007214 · 2020 · External reference
Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19
10.1182/blood.2020007252 · 2020 · External reference
Platelet-monocyte interaction amplifies thromboinflammation through tissue factor signaling in COVID-19
10.1182/bloodadvances.2021006680 · 2022 · External reference
Remdesivir for the Treatment of Covid-19 - Final Report
10.1056/nejmoa2007764 · 2020 · External reference
Unresolved reference
2025 · External reference
Evaluation of abnormal liver-enzyme results in asymptomatic patients
10.1056/nejm200004273421707 · 2000 · External reference
Platelets and COVID-19
10.1161/circresaha.120.318218 · 2020 · External reference
Platelet-TLR7 mediates host survival and platelet count during viral infection in the absence of platelet-dependent thrombosis
10.1182/blood-2013-11-536003 · 2014 · External reference
Pollen-derived RNAs Are Found in the Human Circulation
10.1016/j.isci.2019.08.035 · 2019 · External reference
Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood
10.1038/nm1565 · 2007 · External reference
TLR10 Is a Negative Regulator of Both MyD88-Dependent and -Independent TLR Signaling
10.4049/jimmunol.1502599 · 2016 · External reference
Past, present, and future perspectives of plasminogen activator inhibitor 1 (PAI-1)
10.1055/s-0042-1758791 · 2023 · External reference
Targeting protease nexin-1, a natural anticoagulant serpin, to control bleeding and improve hemostasis in hemophilia
10.1182/blood.2019000281 · 2019 · External reference
Cryo-EM structure of the human native plasma coagulation factor XIII complex
10.1182/blood.2024025369 · 2025 · External reference
Mechanisms of anticoagulant and cytoprotective actions of the protein C pathway
10.1111/jth.12247 · 2013 · External reference
Urokinase-Type Plasminogen Activator Receptor (uPAR) in Inflammation and Disease: A Unique Inflammatory Pathway Activator
10.3390/biomedicines12061167 · 2024 · External reference
Granulocyte microvesicles with a high plasmin generation capacity promote clot lysis and improve outcome in septic shock
10.1182/blood.2021013328 · 2022 · External reference
Roles of Factor XII in Innate Immunity
10.3389/fimmu.2019.02011 · 2019 · External reference
Factor XII and uPAR upregulate neutrophil functions to influence wound healing
10.1172/jci92880 · 2018 · External reference
Innate immune receptors in platelets and platelet-leukocyte interactions
10.1002/jlb.4mr0620-701r · 2020 · External reference
Platelet activation and aggregation promote lung inflammation and influenza virus pathogenesis
10.1164/rccm.201406-1031oc · 2015 · External reference
X-ray-based virtual slicing of TB-infected lungs
10.1038/s41598-019-55986-y · 2019 · External reference
Thromboinflammation in COVID-19 acute lung injury
2020 · External reference
COVID-19: thrombosis, thromboinflammation, and anticoagulation considerations
10.1111/ijlh.13500 · 2021 · External reference
The Gp1ba-Cre transgenic mouse: a new model to delineate platelet and leukocyte functions
10.1182/blood-2018-09-877787 · 2019 · External reference
The role of platelets in mediating a response to human influenza infection
10.1038/s41467-019-09607-x · 2019 · External reference
A multi-center, prospective cohort study of whole blood gene expression in the tuberculosis-diabetes interaction
10.1038/s41598-023-34847-9 · 2023 · External reference
Blood transcriptome responses in patients correlate with severity of COVID-19 disease
10.3389/fimmu.2022.1043219 · 2023 · External reference
Dysregulated transcriptional responses to SARS-CoV-2 in the periphery
10.1038/s41467-021-21289-y · 2021 · External reference
A multi-center, prospective cohort study of whole blood gene expression in the tuberculosis-diabetes interaction
10.1038/s41598-023-34847-9 · 2023 · External reference
An integrative multi-omics approach to characterize interactions between tuberculosis and diabetes mellitus
10.1016/j.isci.2024.109135 · 2024 · External reference
Blood transcriptome responses in patients correlate with severity of COVID-19 disease
10.3389/fimmu.2022.1043219 · 2022 · External reference
Pathway and network analyses identify growth factor signaling and MMP9 as potential mediators of mitochondrial dysfunction in severe COVID-19
10.3390/ijms24032524 · 2023 · External reference
Dysregulated transcriptional responses to SARS-CoV-2 in the periphery
10.1038/s41467-021-21289-y · 2021 · External reference
An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility
10.1186/s13073-021-00904-z · 2021 · External reference
