Research graph
References from Schistosoma japonicum leishmanolysin SjLLPi1 facilitates the invasion of cercariae into the host skin. Local targets link to admitted publications; unresolved targets remain external evidence.
Review of 2022 WHO guidelines on the control and elimination of schistosomiasis
2022 · External reference
Vaccines for human schistosomiasis: recent progress, new developments and future prospects
10.3390/ijms23042255 · 2022 · External reference
A recent advance in the diagnosis, treatment, and vaccine development for human schistosomiasis
10.3390/tropicalmed9100243 · 2024 · External reference
Prevalence of human Schistosoma mansoni infection in endemic regions (2010-2024): a systematic review and meta-analysis
10.1016/j.eclinm.2024.102855 · 2024 · External reference
Transmission-blocking vaccines against schistosomiasis iaponica
10.3390/ijms25031707 · 2024 · External reference
The genetic variation of different developmental stages of Schistosoma japonicum: do the distribution in snails and pairing preference benefit the transmission?
10.1186/s13071-020-04240-w · 2020 · External reference
Schistosomiasis-from immunopathology to vaccines
10.1007/s00281-020-00789-x · 2020 · External reference
Schistosomiasis
10.1007/978-3-030-18616-6_3 · 2019 · External reference
The infection of human skin by schistosome cercariae: studies using Franz cells
10.1017/s0031182099006034 · 2000 · External reference
Modulation of the host’s immune response by schistosome larvae
10.1111/j.1365-3024.2005.00789.x · 2005 · External reference
Differential proteomic analysis of laser-microdissected penetration glands of avian schistosome cercariae with a focus on proteins involved in host invasion
10.1016/j.ijpara.2021.12.003 · 2022 · External reference
Schistosoma mansoni: cercaria to schistosomule
10.1016/s0065-308x(08)60388-7 · 1974 · External reference
Invasion of skin by schistosome cercariae: some neglected facts
10.1016/s1471-4922(02)00019-3 · 2003 · External reference
Schistosome invasion of human skin and degradation of dermal elastin are mediated by a single serine protease
10.1074/jbc.m006997200 · 2000 · External reference
Immune evasion strategies of schistosomes
10.3389/fimmu.2020.624178 · 2021 · External reference
Proteases from Schistosoma mansoni cercariae cleave IgE at solvent exposed interdomain regions
10.1016/j.molimm.2007.05.021 · 2008 · External reference
Enzyme activity of Schistosoma japonicum cercarial elastase SjCE-2b ascertained by in vitro refolded recombinant protein
10.1016/j.actatropica.2018.07.009 · 2018 · External reference
Schistosome secretomes
10.1016/j.actatropica.2022.106676 · 2022 · External reference
Schistosoma mansoni, S. haematobium, and S. japonicum: early events associated with penetration and migration of schistosomula through human skin
10.1016/s0014-4894(03)00024-9 · 2002 · External reference
Schistosome migration in the definitive host
10.1371/journal.pntd.0007951 · 2020 · External reference
Proteomic analysis on cercariae and Schistosomula in reference to potential proteases involved in host invasion of Schistosoma japonicum larvae
10.1021/acs.jproteome.5b00465 · 2015 · External reference
Quantum biochemistry screening and in vitro evaluation of leishmania metalloproteinase inhibitors
10.3390/ijms23158553 · 2022 · External reference
The crystal structure of the Leishmania major surface proteinase leishmanolysin (gp63)
10.1016/s0969-2126(98)00104-x · 1998 · External reference
Variable surface glycoprotein from trypanosoma brucei undergoes cleavage by matrix metalloproteinases: an in silico approach
10.3390/pathogens8040178 · 2019 · External reference
The major surface protease (MSP or GP63) of Leishmania sp. Biosynthesis, regulation of expression, and function
10.1016/s0166-6851(03)00211-1 · 2003 · External reference
Schistosoma japonicum cathepsin B2 (SjCB2) facilitates parasite invasion through the skin
2020 · External reference
Preparation of monoclonal antibodies: strategies and procedures
10.1016/0076-6879(81)73054-4 · 1981 · External reference
An atlas for Schistosoma mansoni organs and life-cycle stages using cell type-specific markers and confocal microscopy
10.1371/journal.pntd.0001009 · 2011 · External reference
Immunolocalization of anti-hsf1 to the acetabular glands of infectious schistosomes suggests a non-transcriptional function for this transcriptional activator
10.1371/journal.pntd.0003051 · 2014 · External reference
Heat shock protein 60 in eggs specifically induces tregs and reduces liver immunopathology in mice with Schistosomiasis japonica
10.1371/journal.pone.0139133 · 2015 · External reference
Metalloproteinases and their inhibitors: potential for the development of new therapeutics
10.3390/cells9051313 · 2020 · External reference
Biocatalyst-artificial metalloenzyme cascade based on alcohol dehydrogenase
10.1039/c8sc02371a · 2018 · External reference
Structural analysis of metal chelation of the metalloproteinase thermolysin by 1,10-phenanthroline
10.1016/j.jinorgbio.2020.111319 · 2021 · External reference
Comparative transcriptome profiles of Schistosoma japonicum larval stages: Implications for parasite biology and host invasion
10.1371/journal.pntd.0009889 · 2022 · External reference
Macrophage cytotoxicity against schistosomula of Schistosoma mansoni involves arginine-dependent production of reactive nitrogen intermediates
10.4049/jimmunol.143.12.4208 · 1989 · External reference
Macrophages as effector cells of protective immunity in murine schistosomiasis. VI. T cell-dependent, lymphokine-mediated, activation of macrophages in response to Schistosoma mansoni antigens
10.4049/jimmunol.131.3.1481 · 1983 · External reference
Nitrogen oxide in host defense against parasites
10.1006/meth.1996.0072 · 1996 · External reference
A comparative study of the death of schistosomula of Schistosoma haematobium and Schistosoma mansoni in the skin of mice and hamsters
10.1017/s0022149x00028820 · 1976 · External reference
Proteomic anatomy of human skin
10.1016/j.jprot.2013.03.019 · 2013 · External reference
Defining keratin protein function in skin epithelia: epidermolysis bullosa simplex and its aftermath
10.1038/jid.2011.450 · 2012 · External reference
Skin collagen through the lifestages: importance for skin health and beauty
10.20517/2347-9264.2020.153 · 2021 · External reference
Expression profile of the Schistosoma japonicum degradome reveals differential protease expression patterns and potential anti-schistosomal intervention targets
2014 · External reference
Matrix metalloproteinases: how much can they do?
10.3390/ijms21082678 · 2020 · External reference
Catalytic domain architecture of metzincin metalloproteases
10.1074/jbc.r800069200 · 2009 · External reference
Gene expression patterns in larval Schistosoma mansoni associated with infection of the mammalian host
2011 · External reference
The epigenome of Schistosoma mansoni provides insight about how cercariae poise transcription until infection
10.1371/journal.pntd.0003853 · 2015 · External reference
A metalloprotease produced by larval Schistosoma mansoni facilitates infection establishment and maintenance in the snail host by interfering with immune cell function
10.1371/journal.ppat.1007393 · 2018 · External reference
Human schistosomiasis
10.1016/s0140-6736(06)69440-3 · 2006 · External reference
Schistosoma mansoni immunomodulatory molecule Sm16/SPO-1/SmSLP is a member of the trematode-specific helminth defence molecules (HDMs)
10.1371/journal.pntd.0008470 · 2020 · External reference
Leishmania-induced inactivation of the macrophage transcription factor AP-1 is mediated by the parasite metalloprotease GP63
10.1371/journal.ppat.1001148 · 2010 · External reference
Leishmania GP63 alters host signaling through cleavage-activated protein tyrosine phosphatases
10.1126/scisignal.2000213 · 2009 · External reference
Revisiting leishmania GP63 host cell targets reveals a limited spectrum of substrates
2022 · External reference
The effects of Leishmania RNA virus 2 (LRV2) on the virulence factors of L. major and pro-inflammatory biomarkers: an in vitro study on human monocyte cell line (THP-1)
10.1186/s12866-023-03140-0 · 2023 · External reference
Recombinant glycoprotein 63 (Gp63) of Trypanosoma carassii suppresses antimicrobial responses of goldfish (Carassius auratus L.) monocytes and macrophages
10.1016/j.ijpara.2012.04.012 · 2012 · External reference
