Research graph
References from CK2 derived from brain microvascular endothelial cells induces astrocyte inflammatory response in Escherichia coli-induced meningitis. Local targets link to admitted publications; unresolved targets remain external evidence.
Global and regional risk of disabling sequelae from bacterial meningitis: a systematic review and meta-analysis
10.1016/s1473-3099(10)70048-7 · 2010 · External reference
Blood-Brain Barrier Integrity Damage in Bacterial Meningitis: The Underlying Link, Mechanisms, and Therapeutic Targets
10.3390/ijms24032852 · 2023 · External reference
Acute bacterial meningitis in infants and children
10.1016/s1473-3099(09)70306-8 · 2010 · External reference
The K1 capsule is the critical determinant in the development of Escherichia coli meningitis in the rat
10.1172/jci115965 · 1992 · External reference
Human Meningitis-Associated Escherichia coli
2016 · External reference
Astrocyte-immune cell interactions in physiology and pathology
10.1016/j.immuni.2021.01.013 · 2021 · External reference
Emerging role of non-coding RNAs in neuroinflammation mediated by microglia and astrocytes
10.1186/s12974-023-02856-0 · 2023 · External reference
Questions and (some) answers on reactive astrocytes
10.1002/glia.23687 · 2019 · External reference
Neuroinflammatory Processes, A1 Astrocyte Activation and Protein Aggregation in the Retina of Alzheimer’s Disease Patients, Possible Biomarkers for Early Diagnosis
10.3389/fnins.2019.00925 · 2019 · External reference
Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease
10.1038/s41591-018-0051-5 · 2018 · External reference
Neurotoxic reactive astrocytes are induced by activated microglia
10.1038/nature21029 · 2017 · External reference
Endothelial cells regulate astrocyte to neural progenitor cell trans-differentiation in a mouse model of stroke
10.1038/s41467-022-35498-6 · 2022 · External reference
Neuroinflammation Plays a Critical Role in Cerebral Cavernous Malformation Disease
10.1161/circresaha.122.321129 · 2022 · External reference
Activated endothelial cells induce a distinct type of astrocytic reactivity
10.1038/s42003-022-03237-8 · 2022 · External reference
One-thousand-and-one substrates of protein kinase CK2?
10.1096/fj.02-0473rev · 2003 · External reference
Protein kinase CK2, an important regulator of the inflammatory response?
10.1007/s00109-008-0352-0 · 2008 · External reference
Therapeutic targeting of CK2 in acute and chronic leukemias
10.1038/leu.2017.301 · 2018 · External reference
Casein kinase II interacts with the bZIP domains of several transcription factors
10.1093/nar/26.16.3854 · 1998 · External reference
Ecto-protein kinase CK2, the neglected form of CK2
2018 · External reference
Genome analysis and in vivo virulence of porcine extraintestinal pathogenic Escherichia coli strain PCN033
10.1186/s12864-015-1890-9 · 2015 · External reference
Endothelial autophagy deficiency induces IL6 - dependent endothelial mesenchymal transition and organ fibrosis
10.1080/15548627.2020.1713641 · 2020 · External reference
Interleukin-22 Contributes to Blood-Brain Barrier Disruption via STAT3/VEGFA Activation in Escherichia coli Meningitis
10.1021/acsinfecdis.3c00668 · 2024 · External reference
Exosomes Derived from Meningitic Escherichia coli-Infected Brain Microvascular Endothelial Cells Facilitate Astrocyte Activation
10.1007/s12035-024-04044-4 · 2024 · External reference
Adenosine triggers early astrocyte reactivity that provokes microglial responses and drives the pathogenesis of sepsis-associated encephalopathy in mice
10.1038/s41467-024-50466-y · 2024 · External reference
Phenotype, differentiation, and function differ in rat and mouse neocortical astrocytes cultured under the same conditions
10.1016/j.jneumeth.2012.09.016 · 2013 · External reference
Isolation of endothelial cells, pericytes and astrocytes from mouse brain
10.1371/journal.pone.0226302 · 2019 · External reference
Astrocyte-Derived TGFβ1 Facilitates Blood-Brain Barrier Function via Non-Canonical Hedgehog Signaling in Brain Microvascular Endothelial Cells
10.3390/brainsci11010077 · 2021 · External reference
Quantifying Microglia Morphology from Photomicrographs of Immunohistochemistry Prepared Tissue Using ImageJ
2018 · External reference
Heterogeneous nuclear ribonucleoprotein A2 interacts with protein kinase CK2
10.1006/bbrc.1999.0849 · 1999 · External reference
Roles of neuropathology-associated reactive astrocytes: a systematic review
10.1186/s40478-023-01526-9 · 2023 · External reference
Microglia: Housekeeper of the Central Nervous System
10.1007/s10571-017-0504-2 · 2018 · External reference
Microglial control of astrocytes in response to microbial metabolites
10.1038/s41586-018-0119-x · 2018 · External reference
Genomic analysis of reactive astrogliosis
10.1523/jneurosci.6221-11.2012 · 2012 · External reference
Haemophilus parasuis encodes two functional cytolethal distending toxins: CdtC contains an atypical cholesterol recognition/interaction region
10.1371/journal.pone.0032580 · 2012 · External reference
Identifying interaction motifs in CK2beta--a ubiquitous kinase regulatory subunit
10.1016/j.tibs.2006.10.005 · 2006 · External reference
Disruption of CK2beta in embryonic neural stem cells compromises proliferation and oligodendrogenesis in the mouse telencephalon
10.1128/mcb.01566-09 · 2010 · External reference
The alpha catalytic subunit of protein kinase CK2 is required for mouse embryonic development
10.1128/mcb.01119-07 · 2008 · External reference
Protein kinase casein kinase 2 holoenzyme produced ectopically in human cells can be exported to the external side of the cellular membrane
10.1073/pnas.0501074102 · 2005 · External reference
Human astrocytes: structure and functions in the healthy brain
10.1007/s00429-017-1383-5 · 2017 · External reference
Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation
10.1038/nm.3681 · 2014 · External reference
STAT1 Signaling in Astrocytes Is Essential for Control of Infection in the Central Nervous System
10.1128/mbio.01881-16 · 2016 · External reference
The role of astrocyte in neuroinflammation in traumatic brain injury
10.1016/j.bbadis.2023.166992 · 2024 · External reference
Glial fibrillary acidic protein in cryogenic lesions of the rat brain
10.1016/0304-3940(81)90052-5 · 1981 · External reference
Interactions between blood-borne Streptococcus pneumoniae and the blood-brain barrier preceding meningitis
10.1371/journal.pone.0068408 · 2013 · External reference
Toll-like receptor 4 activation enhances Orai1-mediated calcium signal promoting cytokine production in spinal astrocytes
10.1016/j.ceca.2022.102619 · 2022 · External reference
Microglial NLRP3 inflammasome activates neurotoxic astrocytes in depression-like mice
10.1016/j.celrep.2022.111532 · 2022 · External reference
miR-141-3p inhibits the activation of astrocytes and the release of inflammatory cytokines in bacterial meningitis through down-regulating HMGB1
10.1016/j.brainres.2021.147611 · 2021 · External reference
Self-extracellular RNA promotes pro-inflammatory response of astrocytes to exogenous and endogenous danger signals
10.1186/s12974-021-02286-w · 2021 · External reference
The Neurotropic Parasite Toxoplasma gondii Induces Astrocyte Polarization Through NFκB Pathway
10.3389/fmed.2019.00267 · 2019 · External reference
Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype
10.1038/s41419-020-2565-2 · 2020 · External reference
Protein Kinase CK2 Promotes Proliferation, Abnormal Differentiation, and Proinflammatory Cytokine Production of Keratinocytes via Regulation of STAT3 and Akt Pathways in Psoriasis
10.1016/j.ajpath.2023.01.016 · 2023 · External reference
Protein kinase CK2 - diverse roles in cancer cell biology and therapeutic promise
10.1007/s11010-022-04558-2 · 2023 · External reference
Protein Kinase CK2, a Potential Therapeutic Target in Carcinoma Management
10.31557/apjcp.2019.20.1.23 · 2019 · External reference
CK2-dependent phosphorylation of occludin regulates the interaction with ZO-proteins and tight junction integrity
10.1186/1478-811x-11-40 · 2013 · External reference
The complex STATes of astrocyte reactivity: How are they controlled by the JAK-STAT3 pathway?
10.1016/j.neuroscience.2016.05.043 · 2016 · External reference
Inhibition of astroglial nuclear factor kappaB reduces inflammation and improves functional recovery after spinal cord injury
10.1084/jem.20041918 · 2005 · External reference
Involvement of p38 MAPK in reactive astrogliosis induced by ischemic stroke
10.1016/j.brainres.2014.01.013 · 2014 · External reference
Calcineurin and glial signaling: neuroinflammation and beyond
10.1186/s12974-014-0158-7 · 2014 · External reference
Protein kinase CK2 regulates AKT, NF-κB and STAT3 activation, stem cell viability and proliferation in acute myeloid leukemia
10.1038/leu.2016.209 · 2017 · External reference
MYH9: Structure, functions and role of non-muscle myosin IIA in human disease
10.1016/j.gene.2018.04.048 · 2018 · External reference
Myosin IIA regulates cell motility and actomyosin-microtubule crosstalk
10.1038/ncb1540 · 2007 · External reference
Signaling via the angiotensin-converting enzyme results in the phosphorylation of the nonmuscle myosin heavy chain IIA
10.1124/mol.105.016733 · 2006 · External reference
Fibroblast growth factor-2 binds to the regulatory beta subunit of CK2 and directly stimulates CK2 activity toward nucleolin
10.1074/jbc.271.40.24781 · 1996 · External reference
Mucin 17 inhibits the progression of human gastric cancer by limiting inflammatory responses through a MYH9-p53-RhoA regulatory feedback loop
10.1186/s13046-019-1279-8 · 2019 · External reference
