Research graph
References from Mycobacterium tuberculosis impairs protective cytokine production via transcription factor MafB manipulation. Local targets link to admitted publications; unresolved targets remain external evidence.
The immune response in tuberculosis
10.1146/annurev-immunol-032712-095939 · 2013 · External reference
Unresolved reference
2024 · External reference
10 Years of GWAS Discovery: Biology, Function, and Translation
10.1016/j.ajhg.2017.06.005 · 2017 · External reference
Genome-wide SNP-based linkage analysis of tuberculosis in Thais
10.1038/gene.2008.81 · 2009 · External reference
Genome-wide association studies of tuberculosis in Asians identify distinct at-risk locus for young tuberculosis
10.1038/jhg.2012.35 · 2012 · External reference
Diagnostic value of blood gene expression signatures in active tuberculosis in Thais: a pilot study
10.1038/gene.2015.4 · 2015 · External reference
An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis
10.1038/nature09247 · 2010 · External reference
The Maf transcription factors: regulators of differentiation
10.1016/s0968-0004(97)01105-5 · 1997 · External reference
MafB Is Critical for Glucagon Production and Secretion in Mouse Pancreatic α Cells In Vivo
10.1128/mcb.00504-17 · 2018 · External reference
MafB is essential for renal development and F4/80 expression in macrophages
10.1128/mcb.00001-06 · 2006 · External reference
MafB Restricts M-CSF-Dependent Myeloid Commitment Divisions of Hematopoietic Stem Cells
10.1016/j.cell.2009.04.057 · 2009 · External reference
Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages
10.1038/ni.2419 · 2012 · External reference
Transcription factor MafB-mediated inhibition of type I interferons in plasmacytoid dendritic cells
10.1093/intimm/dxab103 · 2022 · External reference
MafB is an interaction partner and repressor of Ets-1 that inhibits erythroid differentiation
10.1016/s0092-8674(00)81081-8 · 1996 · External reference
The transcription factor MafB promotes anti-inflammatory M2 polarization and cholesterol efflux in macrophages
10.1038/s41598-017-07381-8 · 2017 · External reference
The transcription factor MafB antagonizes antiviral responses by blocking recruitment of coactivators to the transcription factor IRF3
10.1038/ni.1897 · 2010 · External reference
Transcription Factor MafB Suppresses Type I Interferon Production by CD14+ Monocytes in Patients With Chronic Hepatitis C
10.3389/fmicb.2019.01814 · 2019 · External reference
MafB is a critical regulator of complement component C1q
10.1038/s41467-017-01711-0 · 2017 · External reference
IRF5:RelA interaction targets inflammatory genes in macrophages
10.1016/j.celrep.2014.07.034 · 2014 · External reference
Maf nuclear oncoprotein recognizes sequences related to an AP-1 site and forms heterodimers with both Fos and Jun
1994 · External reference
Retinoic acid and the transcription factor MafB act together and differentially to regulate aggrecan and matrix metalloproteinase gene expression in neonatal chondrocytes
10.1002/jcb.24387 · 2013 · External reference
Transcription factor MAFB controls type I and II interferon response-mediated host immunity in Mycobacterium tuberculosis-infected macrophages
10.3389/fmicb.2022.962306 · 2022 · External reference
Tuberculosis in otherwise healthy adults with inherited TNF deficiency
10.1038/s41586-024-07866-3 · 2024 · External reference
Immunology of tuberculosis
10.1146/annurev.immunol.19.1.93 · 2001 · External reference
Anti-tumour necrosis factor agents and tuberculosis risk: mechanisms of action and clinical management
10.1016/s1473-3099(03)00545-0 · 2003 · External reference
Role of IL-12 in macrophage activation during intracellular infection: IL-12 and mycobacteria synergistically release TNF-α and nitric oxide from macrophages via IFN-γ induction
10.1189/jlb.68.6.897 · 2000 · External reference
Differential expression patterns of MafB and c-Maf in macrophages in vivo and in vitro
10.1016/j.bbrc.2016.03.063 · 2016 · External reference
MAFB Determines Human Macrophage Anti-Inflammatory Polarization: Relevance for the Pathogenic Mechanisms Operating in Multicentric Carpotarsal Osteolysis
10.4049/jimmunol.1601667 · 2017 · External reference
Control of the Inflammatory Macrophage Transcriptional Signature by miR-155
10.1371/journal.pone.0159724 · 2016 · External reference
Expression of MAF bZIP transcription factor B protects against ulcerative colitis through the inhibition of the NF-κB pathway
2024 · External reference
MAFB in macrophages regulates cold-induced neuronal density in brown adipose tissue
10.1016/j.celrep.2024.113978 · 2024 · External reference
MafB is a downstream target of the IL-10/STAT3 signaling pathway, involved in the regulation of macrophage de-activation
10.1016/j.bbamcr.2014.01.021 · 2014 · External reference
Acute TREM2 inhibition depletes MAFB-high microglia and hinders remyelination
2025 · External reference
TREM2 Promotes Immune Evasion by Mycobacterium tuberculosis in Human Macrophages
10.1128/mbio.01456-22 · 2022 · External reference
TREM2 is a receptor for non-glycosylated mycolic acids of mycobacteria that limits anti-mycobacterial macrophage activation
10.1038/s41467-021-22620-3 · 2021 · External reference
The endogenous retinoic acid receptor pathway is exploited by Mycobacterium tuberculosis during infection, both in vitro and in vivo
10.4049/jimmunol.2200555 · 2023 · External reference
Role of MafB in macrophages
10.1538/expanim.19-0076 · 2020 · External reference
Mycobacterium tuberculosis modulates macrophage lipid-sensing nuclear receptors PPARγ and TR4 for survival
10.4049/jimmunol.1103038 · 2012 · External reference
Cutting edge: Vitamin D regulates lipid metabolism in Mycobacterium tuberculosis infection
10.4049/jimmunol.1400736 · 2014 · External reference
MafB deficiency causes defective respiratory rhythmogenesis and fatal central apnea at birth
10.1038/nn1129 · 2003 · External reference
Interleukin 12 (IL-12) is crucial to the development of protective immunity in mice intravenously infected with mycobacterium tuberculosis
10.1084/jem.186.1.39 · 1997 · External reference
Tumor necrosis factor-alpha is required in the protective immune response against Mycobacterium tuberculosis in mice
10.1016/1074-7613(95)90001-2 · 1995 · External reference
Local role for tumor necrosis factor alpha in the pulmonary inflammatory response to Mycobacterium tuberculosis infection
10.1128/iai.70.4.2082-2089.2002 · 2002 · External reference
Phenotypic analysis of mice carrying human-type MAFB p.Leu239Pro mutation
10.1016/j.bbrc.2019.12.033 · 2020 · External reference
Mice harboring an MCTO mutation exhibit renal failure resembling nephropathy in human patients
10.1538/expanim.18-0093 · 2019 · External reference
A role for the apoptosis inhibitory factor AIM/Spalpha/Api6 in atherosclerosis development
10.1016/j.cmet.2005.02.002 · 2005 · External reference
Morphoproteomics Identifies the Foamy Alveolar Macrophage as an M2 Phenotype with PD-L1 Expression in the Early Lesion of Post-Primary Tuberculosis: Implications for Host Immune Surveillance and Therapy
2020 · External reference
Host-directed therapies for bacterial and viral infections
10.1038/nrd.2017.162 · 2018 · External reference
Spi-B is critical for plasmacytoid dendritic cell function and development
10.1182/blood-2012-06-436527 · 2012 · External reference
PDLIM2-mediated termination of transcription factor NF-kappaB activation by intranuclear sequestration and degradation of the p65 subunit
10.1038/ni1464 · 2007 · External reference
