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References from Discovery and mechanistic insights of dibenzoylmethane as a broad spectrum inhibitor of coronavirus. Local targets link to admitted publications; unresolved targets remain external evidence.
Evaluation of human coronavirus OC43 and SARS-COV-2 in children with respiratory tract infection during the COVID-19 pandemic
10.1002/jmv.27460 · 2022 · External reference
Non-invasive bioluminescence imaging of HCoV-OC43 infection and therapy in the central nervous system of live mice
10.1016/j.antiviral.2019.104646 · 2020 · External reference
More than just a common cold: Endemic coronaviruses OC43, HKU1, NL63, and 229E associated with severe acute respiratory infection and fatality cases among healthy adults
10.1002/jmv.26362 · 2021 · External reference
A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence
10.1038/nm.3985 · 2015 · External reference
A bat MERS-like coronavirus circulates in pangolins and utilizes human DPP4 and host proteases for cell entry
10.1016/j.cell.2023.01.019 · 2023 · External reference
A critical overview of current progress for COVID-19: development of vaccines, antiviral drugs, and therapeutic antibodies
10.1186/s12929-022-00852-9 · 2022 · External reference
Enhanced neutralization resistance of SARS-CoV-2 Omicron subvariants BQ.1, BQ.1.1, BA.4.6, BF.7, and BA.2.75.2
2023 · External reference
Multiple pathways for SARS-CoV-2 resistance to nirmatrelvir
10.1038/s41586-022-05514-2 · 2023 · External reference
Accelerating antiviral drug discovery: lessons from COVID-19
10.1038/s41573-023-00692-8 · 2023 · External reference
The potential chemical structure of anti-SARS-CoV-2 RNA-dependent RNA polymerase
10.1002/jmv.25761 · 2020 · External reference
Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients
10.1038/s41401-020-0483-6 · 2020 · External reference
Safe, high-throughput screening of natural compounds of MERS-CoV entry inhibitors using a pseudovirus expressing MERS-CoV spike protein
10.1016/j.ijantimicag.2018.05.003 · 2018 · External reference
Cepharanthine analogs mining and genomes of Stephania accelerate anti-coronavirus drug discovery
10.1038/s41467-024-45690-5 · 2024 · External reference
Inhibition of airway inflammation by the roots of Angelica decursiva and its constituent, columbianadin
10.1016/j.jep.2014.07.033 · 2014 · External reference
Chemoprevention of familial adenomatous polyposis by natural dietary compounds sulforaphane and dibenzoylmethane alone and in combination in ApcMin/+ mouse
10.1158/0008-5472.can-07-1112 · 2007 · External reference
Role of alpha1 acid glycoprotein in the in vivo resistance of human BCR-ABL(+) leukemic cells to the abl inhibitor STI571
10.1093/jnci/92.20.1641 · 2000 · External reference
Pharmacogenomic profiling of intra-tumor heterogeneity using a large organoid biobank of liver cancer
10.1016/j.ccell.2024.03.004 · 2024 · External reference
A viral RNA-dependent RNA polymerase inhibitor VV116 broadly inhibits human coronaviruses and has synergistic potency with 3CLpro inhibitor nirmatrelvir
10.1038/s41392-023-01587-1 · 2023 · External reference
Attenuation of Equine Lentivirus Alters Mitochondrial Protein Expression Profile from Inflammation to Apoptosis
2019 · External reference
Human Cytomegalovirus Manipulates Syntaxin 6 for Successful Trafficking and Subsequent Infection of Monocytes
10.1128/jvi.00819-22 · 2022 · External reference
Serine-arginine protein kinases and their targets in viral infection and their inhibition
10.1007/s00018-023-04808-6 · 2023 · External reference
Coronaviruses exploit a host cysteine-aspartic protease for replication
2022 · External reference
The role of cell death in SARS-CoV-2 infection
10.1038/s41392-023-01580-8 · 2023 · External reference
Host MOV10 is induced to restrict herpes simplex virus 1 lytic infection by promoting type I interferon response
10.1371/journal.ppat.1010301 · 2022 · External reference
A CRISPR-Cas9 knockout screening identifies IRF2 as a key driver of OAS3/RNase L-mediated RNA decay during viral infection
2024 · External reference
Natural products as a source of Coronavirus entry inhibitors
10.3389/fcimb.2024.1353971 · 2024 · External reference
Histone deacetylase inhibition reduces deleterious cytokine release induced by ingenol stimulation
10.1016/j.bcp.2021.114844 · 2022 · External reference
Metabolism Study of Veratramine Associated with Neurotoxicity by Using HPLC-MSn
10.1093/chromsci/bmu171 · 2015 · External reference
Dibenzoylmethane derivative inhibits melanoma cancer in vitro and in vivo through induction of intrinsic and extrinsic apoptotic pathways
10.1016/j.cbi.2021.109734 · 2022 · External reference
Inhibition by dietary dibenzoylmethane of mammary gland proliferation, formation of DMBA-DNA adducts in mammary glands, and mammary tumorigenesis in Sencar mice
10.1016/s0304-3835(01)00506-7 · 2001 · External reference
Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense
10.1016/j.cell.2020.03.040 · 2020 · External reference
An AMPK-caspase-6 axis controls liver damage in nonalcoholic steatohepatitis
10.1126/science.aay0542 · 2020 · External reference
Therapeutic potential of Nlrp1 inflammasome, Caspase-1, or Caspase-6 against Alzheimer disease cognitive impairment
10.1038/s41418-021-00881-1 · 2022 · External reference
Activation of Caspase-6 Is Promoted by a Mutant Huntingtin Fragment and Blocked by an Allosteric Inhibitor Compound
10.1016/j.chembiol.2019.07.001 · 2019 · External reference
Knocking down macrophages Caspase-6 through HMGB1 coordinates macrophage trophoblast crosstalk to suppress ferroptosis and alleviate preeclampsia
10.1016/j.intimp.2024.112859 · 2024 · External reference
