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References from The interaction between GCN2 and eIF2 mediates the resistance of cotton bollworm to the Bacillus thuringiensis Cry1Ac toxin. Local targets link to admitted publications; unresolved targets remain external evidence.
Environmental Behaviors of Bacillus thuringiensis (Bt) Insecticidal Proteins and Their Effects on Microbial Ecology
2022 · External reference
Bacillus thuringiensis: a century of research, development and commercial applications
10.1111/j.1467-7652.2011.00595.x · 2011 · External reference
From microbial sprays to insect-resistant transgenic plants: history of the biospesticideBacillus thuringiensis. A review
10.1051/agro/2010027 · 2010 · External reference
Regional pest suppression associated with widespread Bt maize adoption benefits vegetable growers
10.1073/pnas.1720692115 · 2018 · External reference
Global Patterns of Insect Resistance to Transgenic Bt Crops: The First 25 Years
10.1093/jee/toac183 · 2023 · External reference
Bacillus thuringiensis insecticidal three-domain Cry toxins: mode of action, insect resistance and consequences for crop protection
10.1111/j.1574-6976.2012.00341.x · 2013 · External reference
Specificity determinants for Cry insecticidal proteins: Insights from their mode of action
10.1016/j.jip.2016.07.018 · 2017 · External reference
Mechanisms of resistance to commercially relevant entomopathogenic bacteria
10.1016/j.cois.2019.03.007 · 2019 · External reference
Detection and Mechanisms of Resistance Evolved in Insects to Cry Toxins from Bacillus thuringiensis
2014 · External reference
An Overview of Mechanisms of Cry Toxin Resistance in Lepidopteran Insects
10.1093/jee/tow310 · 2017 · External reference
Down-regulation of a novel ABC transporter gene (Pxwhite) is associated with Cry1Ac resistance in the diamondback moth, Plutella xylostella (L.)
10.1016/j.ibmb.2015.01.009 · 2015 · External reference
Reduced cadherin expression associated with resistance to Bt toxin Cry1Ac in pink bollworm
10.1002/ps.5496 · 2020 · External reference
Downregulation and mutation of a Cadherin gene associated with Cry1Ac resistance in the Asian Corn Borer, Ostrinia furnacalis (Guenée)
10.3390/toxins6092676 · 2014 · External reference
Diverse cadherin mutations conferring resistance to Bacillus thuringiensis toxin Cry1Ac in Helicoverpa armigera
10.1016/j.ibmb.2010.01.001 · 2010 · External reference
Diverse genetic basis of field-evolved resistance to Bt cotton in cotton bollworm from China
10.1073/pnas.1200156109 · 2012 · External reference
A Single Point Mutation Resulting in Cadherin Mislocalization Underpins Resistance against Bacillus thuringiensis Toxin in Cotton Bollworm
10.1074/jbc.m116.768671 · 2017 · External reference
FOXA transcriptional factor modulates insect susceptibility to Bacillus thuringiensis Cry1Ac toxin by regulating the expression of toxin-receptor ABCC2 and ABCC3 genes
10.1016/j.ibmb.2017.07.004 · 2017 · External reference
GATAe transcription factor is involved in Bacillus thuringiensis Cry1Ac toxin receptor gene expression inducing toxin susceptibility
10.1016/j.ibmb.2019.103306 · 2020 · External reference
Contribution of the transcription factor SfGATAe to Bt Cry toxin resistance in Spodoptera frugiperda through reduction of ABCC2 expression
10.1016/j.ijbiomac.2024.131459 · 2024 · External reference
MAPK-Activated Transcription Factor PxJun Suppresses PxABCB1 Expression and Confers Resistance to Bacillus thuringiensis Cry1Ac Toxin in Plutella xylostella (L.)
2021 · External reference
A single transcription factor facilitates an insect host combating Bacillus thuringiensis infection while maintaining fitness
10.1038/s41467-022-33706-x · 2022 · External reference
Eukaryotic Translation Initiation Factor 2 Modulates the Expression of Midgut Receptors to Confer Resistance to Bacillus thuringiensis Cry1Ac Toxin in Helicoverpa armigera
2025 · External reference
PERK and GCN2 contribute to eIF2alpha phosphorylation and cell cycle arrest after activation of the unfolded protein response pathway
10.1091/mbc.e05-03-0268 · 2005 · External reference
Eukaryotic initiation factor 2 phosphorylation and translational control in metabolism
10.3945/an.112.002113 · 2012 · External reference
Multiple mechanisms activate GCN2 eIF2 kinase in response to diverse stress conditions
10.1093/nar/gkae006 · 2024 · External reference
Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast
10.1016/0092-8674(92)90193-g · 1992 · External reference
Global phosphoproteomics pinpoints uncharted Gcn2-mediated mechanisms of translational control
10.1016/j.molcel.2021.02.037 · 2021 · External reference
Activation of Gcn2 by small molecules designed to be inhibitors
10.1016/j.jbc.2023.104595 · 2023 · External reference
Bacillus thuringiensis Cry1Ab Domain III β-22 Mutants with Enhanced Toxicity to Spodoptera frugiperda (J. E. Smith)
10.1128/aem.01580-20 · 2020 · External reference
Cadherin Protein Is Involved in the Action of Bacillus thuringiensis Cry1Ac Toxin in Ostrinia furnacalis
10.3390/toxins13090658 · 2021 · External reference
The role of GPI-anchored membrane-bound alkaline phosphatase in the mode of action of Bt Cry1A toxins in the diamondback moth
10.1016/j.fmre.2024.05.007 · 2024 · External reference
The role of eIF2 phosphorylation in cell and organismal physiology: new roles for well-known actors
10.1042/bcj20220068 · 2022 · External reference
Coordinate regulation of eIF2α phosphorylation by PPP1R15 and GCN2 is required during Drosophila development
2013 · External reference
Translation initiation: adept at adapting
10.1016/s0968-0004(99)01457-7 · 1999 · External reference
GCN2-dependent phosphorylation of eukaryotic translation initiation factor-2alpha in Arabidopsis
10.1093/jxb/ern169 · 2008 · External reference
Regulation of G(1) arrest and apoptosis in hypoxia by PERK and GCN2-mediated eIF2alpha phosphorylation
10.1593/neo.91354 · 2010 · External reference
The Gcn2 kinase as a cell cycle regulator
10.4161/cc.6.22.4933 · 2007 · External reference
eIF2α kinases PERK and GCN2 act on FOXO to potentiate FOXO activity
10.1111/gtc.12625 · 2018 · External reference
Quantitative analysis of fitness costs associated with the development of resistance to the Bt toxin Cry1Ac in Helicoverpa armigera
10.1038/srep05629 · 2014 · External reference
An improvement in the technique of artificial raring cotton bollworm
1999 · External reference
Cytotoxicity and binding profiles of activated Cry1Ac and Cry2Ab to three insect cell lines
10.1111/1744-7917.12451 · 2018 · External reference
Up-regulated serpin gene involved in Cry1Ac resistance in Helicoverpa armigera
10.1016/j.pestbp.2022.105269 · 2022 · External reference
Suppression of Calcineurin Enhances the Toxicity of Cry1Ac to Helicoverpa armigera
10.3389/fmicb.2021.634619 · 2021 · External reference
Transcriptomic Responses to Different Cry1Ac Selection Stresses in Helicoverpa armigera
10.3389/fphys.2018.01653 · 2018 · External reference
Endogenous serpin reduces toxicity of Bacillus thuringiensis Cry1Ac against Helicoverpa armigera (Hübner)
10.1016/j.pestbp.2021.104837 · 2021 · External reference
Reduced expression of the P-glycoprotein gene HaABCB1 is linked to resistance to Bacillus thuringiensis Cry1Ac toxin but not Cry2Ab toxin in Helicoverpa armigera
10.1016/j.ijbiomac.2023.127668 · 2023 · External reference
Spodoptera litura autophagy-related protein 1 interacts with autophagy-related protein 5 and enhances its degradation
10.1111/imb.12284 · 2017 · External reference
