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References from A genome-wide analysis of YY1 and TFAP2 competition on overlapping motifs reveals their roles in HPV-induced carcinogenesis. Local targets link to admitted publications; unresolved targets remain external evidence.
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
2021 · External reference
Human papillomavirus vaccine coverage surveys in low- and middle-income countries: current efforts and future considerations for very young adolescents
2025 · External reference
Epidemiologic classification of human papillomavirus types associated with cervical cancer
10.1056/nejmoa021641 · 2003 · External reference
The causal relation between human papillomavirus and cervical cancer
10.1136/jcp.55.4.244 · 2002 · External reference
Human papillomavirus is a necessary cause of invasive cervical cancer worldwide
10.1002/(sici)1096-9896(199909)189:1<12::aid-path431>3.0.co;2-f · 1999 · External reference
Unresolved reference
2020 · External reference
The papillomavirus E7 proteins
10.1016/j.virol.2013.04.013 · 2013 · External reference
Papillomavirus E6 oncoproteins
10.1016/j.virol.2013.04.026 · 2013 · External reference
The human papillomavirus E6 protein and its contribution to malignant progression
10.1038/sj.onc.1204869 · 2001 · External reference
Endogenous human papillomavirus E6 and E7 proteins differentially regulate proliferation, senescence, and apoptosis in HeLa cervical carcinoma cells
10.1128/jvi.77.2.1551-1563.2003 · 2003 · External reference
The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
10.1016/0092-8674(90)90409-8 · 1990 · External reference
Mechanisms of transcriptional regulation by p53
10.1038/cdd.2017.174 · 2018 · External reference
Genome-Wide Analysis of p53 Targets Reveals SCN2A as a Novel Player in p53-Induced Cell Arrest in HPV-Positive Cells
10.3390/v16111725 · 2024 · External reference
Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product
10.1002/j.1460-2075.1989.tb08594.x · 1989 · External reference
The regulation of E2F by pRB-family proteins
10.1101/gad.12.15.2245 · 1998 · External reference
Oncogenic HPV promotes the expression of the long noncoding RNA lnc-FANCI-2 through E7 and YY1
2021 · External reference
The HPV E6/E7 Oncogenes: Key Factors for Viral Carcinogenesis and Therapeutic Targets
10.1016/j.tim.2017.07.007 · 2018 · External reference
The oncogenic role of Yin Yang 1
10.1615/critrevoncog.v16.i3-4.30 · 2011 · External reference
YY1 represses human papillomavirus type 16 transcription by quenching AP-1 activity
10.1128/jvi.70.10.6529-6539.1996 · 1996 · External reference
Unresolved reference
2024 · External reference
The E7 oncoprotein is translated from spliced E6*I transcripts in high-risk human papillomavirus type 16- or type 18-positive cervical cancer cell lines via translation reinitiation
10.1128/jvi.80.9.4249-4263.2006 · 2006 · External reference
The combined immunodetection of AP-2alpha and YY1 transcription factors is associated with ERBB2 gene overexpression in primary breast tumors
10.1186/bcr1851 · 2008 · External reference
Yin Yang 1 cooperates with activator protein 2 to stimulate ERBB2 gene expression in mammary cancer cells
10.1074/jbc.m503790200 · 2005 · External reference
Model systems to study the life cycle of human papillomaviruses and HPV-associated cancers
10.1007/s12250-015-3600-9 · 2015 · External reference
microRNAs are biomarkers of oncogenic human papillomavirus infections
10.1073/pnas.1401430111 · 2014 · External reference
Heterodimerization of TFAP2 pioneer factors drives epigenomic remodeling during neural crest specification
10.1101/gr.249680.119 · 2020 · External reference
The AP-2 family of transcription factors
10.1186/gb-2005-6-13-246 · 2005 · External reference
TFAP2C regulates transcription in human naive pluripotency by opening enhancers
10.1038/s41556-018-0089-0 · 2018 · External reference
TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment
2019 · External reference
TFAP2 paralogs facilitate chromatin access for MITF at pigmentation and cell proliferation genes
10.1371/journal.pgen.1010207 · 2022 · External reference
Transcription factor AP2 and its role in epidermal-specific gene expression
10.1073/pnas.88.18.7948 · 1991 · External reference
TFAP2C facilitates somatic cell reprogramming by inhibiting c-Myc-dependent apoptosis and promoting mesenchymal-to-epithelial transition
10.1038/s41419-020-2684-9 · 2020 · External reference
AP2γ regulates neural and epidermal development downstream of the BMP pathway at early stages of ectodermal patterning
10.1038/cr.2012.122 · 2012 · External reference
Krüppel-like factors compete for promoters and enhancers to fine-tune transcription
10.1093/nar/gkx441 · 2017 · External reference
MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat
10.1038/s41467-019-11568-0 · 2019 · External reference
YY1 Is a Structural Regulator of Enhancer-Promoter Loops
10.1016/j.cell.2017.11.008 · 2017 · External reference
ROCK inhibitor and feeder cells induce the conditional reprogramming of epithelial cells
10.1016/j.ajpath.2011.10.036 · 2012 · External reference