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References from The gonococcal vaccine candidate antigen NGO1701 is a N. gonorrhoeae periplasmic copper storage protein. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
External reference
Sexually transmitted infections treatment guidelines, 2021
10.15585/mmwr.rr7004a1 · 2021 · External reference
Antimicrobial resistance expressed by neisseria gonorrhoeae: a major global public health problem in the 21st century
10.1128/microbiolspec.ei10-0009-2015 · 2016 · External reference
Common patterns and unique threats in antimicrobial resistance as demonstrated by global gonococcal surveillance
10.3201/eid3014.240296 · 2024 · External reference
Neisseria gonorrhoeae vaccines: a contemporary overview
10.1128/cmr.00094-23 · 2024 · External reference
Targeting Lipooligosaccharide (LOS) for a Gonococcal Vaccine
10.3389/fimmu.2019.00321 · 2019 · External reference
Preclinical efficacy of a lipooligosaccharide peptide mimic candidate gonococcal vaccine
10.1128/mbio.02552-19 · 2019 · External reference
Integrated bioinformatic analyses and immune characterization of new Neisseria gonorrhoeae vaccine antigens expressed during natural mucosal infection
10.3390/vaccines7040153 · 2019 · External reference
The gonococcal transcriptome during infection of the lower genital tract in women
10.1371/journal.pone.0133982 · 2015 · External reference
Transcriptome analysis of neisseria gonorrhoeae during natural infection reveals differential expression of antibiotic resistance determinants between men and women
10.1128/mspheredirect.00312-18 · 2018 · External reference
In vitro pre-clinical evaluation of a gonococcal trivalent candidate vaccine identified by transcriptomics
10.3390/vaccines11121846 · 2023 · External reference
A four-helix bundle stores copper for methane oxidation
10.1038/nature14854 · 2015 · External reference
Bacterial cytosolic proteins with a high capacity for Cu(I) that protect against copper toxicity
10.1038/srep39065 · 2016 · External reference
Copper microenvironments in the human body define patterns of copper adaptation in pathogenic bacteria
10.1371/journal.ppat.1010617 · 2022 · External reference
Copper homeostasis in Streptococcus and Neisseria: known knowns and unknown knowns
10.1016/bs.ampbs.2024.11.001 · 2025 · External reference
Open-access bacterial population genomics: BIGSdb software, the PubMLST.org website and their applications
10.12688/wellcomeopenres.14826.1 · 2018 · External reference
The Gonococcal NlpD protein facilitates cell separation by activating peptidoglycan cleavage by AmiC
10.1128/jb.00540-15 · 2015 · External reference
A subpopulation of intracellular Neisseria gonorrhoeae escapes autophagy-mediated killing inside epithelial cells
2019 · External reference
In vitro activity of quaternary ammonium surfactants against Streptococcal, Chlamydial, and Gonococcal Infective Agents
10.1128/aac.00166-16 · 2016 · External reference
Neisseria gonorrhoeae infection causes a G1 arrest in human epithelial cells
10.1096/fj.06-6675com · 2007 · External reference
Serum bactericidal antibody assays - The role of complement in infection and immunity
10.1016/j.vaccine.2015.07.019 · 2015 · External reference
Development and validation of a standardized human complement serum bactericidal activity assay to measure functional antibody responses to Neisseria gonorrhoeae
10.1016/j.vaccine.2024.126508 · 2025 · External reference
Assessment of serum bactericidal and opsonophagocytic activity of antibodies to gonococcal vaccine targets
10.1007/978-1-0716-1900-1_19 · 2022 · External reference
Effectiveness of a group B outer membrane vesicle meningococcal vaccine against gonorrhoea in New Zealand: a retrospective case-control study
10.1016/s0140-6736(17)31449-6 · 2017 · External reference
Effectiveness of MenB-4C vaccine against gonorrhea: a systematic review and meta-analysis
10.1093/infdis/jiae383 · 2025 · External reference
The serogroup B meningococcal outer membrane vesicle-based vaccine 4CMenB induces cross-species protection against Neisseria gonorrhoeae
10.1371/journal.ppat.1008602 · 2020 · External reference
OpcA and PorB are novel bactericidal antigens of the 4CMenB vaccine in mice and humans
10.1038/s41541-023-00651-9 · 2023 · External reference
Meningococcal detoxified outer membrane vesicle vaccines enhance gonococcal clearance in a murine infection model
10.1093/infdis/jiab450 · 2022 · External reference
Microencapsulated IL-12 drives genital tract immune responses to intranasal gonococcal outer membrane vesicle vaccine and induces resistance to vaginal infection with diverse strains of Neisseria gonorrhoeae
2023 · External reference
Characterization of outer membrane vesicles released by clinical isolates of Neisseria gonorrhoeae
10.1002/pmic.202300087 · 2024 · External reference
Genetic similarity of gonococcal homologs to meningococcal outer membrane proteins of serogroup B vaccine
2019 · External reference
Proteomics-driven antigen discovery for development of vaccines against gonorrhea
10.1074/mcp.m116.058800 · 2016 · External reference
Preclinical in vivo evaluation of a gonococcal multivalent vaccine containing antigens identified by CASS
2025 · External reference
The transport mechanism of bacterial Cu+-ATPases: distinct efflux rates adapted to different function
10.1007/s10534-010-9404-3 · 2011 · External reference
Phenotypic characterization of a copA mutant of Neisseria gonorrhoeae identifies a link between copper and nitrosative stress
10.1128/iai.06163-11 · 2012 · External reference
A cytosolic copper storage protein provides a second level of copper tolerance in Streptomyces lividans
10.1039/c7mt00299h · 2018 · External reference
Copper delivery to an endospore coat protein of Bacillus subtilis
10.3389/fcell.2022.916114 · 2022 · External reference
Acclimation to nutritional immunity and metal intoxication requires zinc, manganese, and copper homeostasis in the pathogenic Neisseriae
10.3389/fcimb.2022.909888 · 2022 · External reference
Metal piracy by Neisseria gonorrhoeae to overcome human nutritional immunity
10.1371/journal.ppat.1011091 · 2023 · External reference
Lipid-modified azurin of Neisseria gonorrhoeae is not surface exposed and does not interact with the nitrite reductase AniA
10.3389/fmicb.2018.02915 · 2018 · External reference
Biochemical characterization of the copper nitrite reductase from Neisseria gonorrhoeae
10.3390/biom13081215 · 2023 · External reference
A genetic screen reveals a periplasmic copper chaperone required for nitrite reductase activity in pathogenic Neisseria
10.1096/fj.15-270751 · 2015 · External reference
Global network analysis of Neisseria gonorrhoeae identifies coordination between pathways, processes, and regulators expressed during human infection
10.1128/msystems.00729-19 · 2020 · External reference
Epidemiological and clinical observations of gonococcal infections in women and prevention strategies
10.3390/vaccines9040327 · 2021 · External reference
The EMBL-EBI job dispatcher sequence analysis tools framework in 2024
10.1093/nar/gkae241 · 2024 · External reference
IntFOLD: an integrated web resource for high performance protein structure and function prediction
10.1093/nar/gkz322 · 2019 · External reference
GalaxyHomomer: a web server for protein homo-oligomer structure prediction from a monomer sequence or structure
10.1093/nar/gkx246 · 2017 · External reference
RING 4.0: faster residue interaction networks with novel interaction types across over 35,000 different chemical structures
2024 · External reference
Unresolved reference
External reference
Genetic manipulation of Neisseria gonorrhoeae
2011 · External reference
Roles of the recJ and recN genes in homologous recombination and DNA repair pathways of Neisseria gonorrhoeae
10.1128/jb.184.4.919-927.2002 · 2002 · External reference
Basic methods for examining Neisseria gonorrhoeae interactions with host cells in vitro
10.1007/978-1-4939-9496-0_17 · 2019 · External reference