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References from Detection and characterization of Hepatitis B virus double-stranded linear DNA-derived covalently closed circular DNA in chronic hepatitis B patients. Local targets link to admitted publications; unresolved targets remain external evidence.
Molecular virology of hepatitis B virus for clinicians
10.1016/j.cld.2007.08.002 · 2007 · External reference
Molecular biology of hepatitis B virus infection
10.1016/j.virol.2015.02.031 · 2015 · External reference
New Insights on Molecular Mechanism of Hepatitis B Virus Covalently Closed Circular DNA Formation
10.3390/cells9112430 · 2020 · External reference
Mechanism of Hepatitis B Virus cccDNA Formation
10.3390/v13081463 · 2021 · External reference
Hepatitis B virus cccDNA: Formation, regulation and therapeutic potential
10.1016/j.antiviral.2020.104824 · 2020 · External reference
Hepatitis B virus biology
10.1128/mmbr.64.1.51-68.2000 · 2000 · External reference
Characterization of the host factors required for hepadnavirus covalently closed circular (ccc) DNA formation
2012 · External reference
The role of host DNA ligases in hepadnavirus covalently closed circular DNA formation
10.1371/journal.ppat.1006784 · 2017 · External reference
Infection of ducklings with virus particles containing linear double-stranded duck hepatitis B virus DNA: illegitimate replication and reversion
10.1128/jvi.72.11.8710-8717.1998 · 1998 · External reference
Illegitimate replication of linear hepadnavirus DNA through nonhomologous recombination
10.1128/jvi.69.7.4029-4036.1995 · 1995 · External reference
Formation of hepatitis B virus covalently closed circular DNA: removal of genome-linked protein
10.1128/jvi.02721-06 · 2007 · External reference
Covalently closed circular viral DNA formed from two types of linear DNA in woodchuck hepatitis virus-infected liver
10.1128/jvi.70.7.4567-4575.1996 · 1996 · External reference
Hepatitis B virus X protein counteracts high mobility group box 1 protein-mediated epigenetic silencing of covalently closed circular DNA
2022 · External reference
Naturally occurring deletion/insertion mutations within HBV whole genome sequences in HBeAg-positive chronic hepatitis B patients are correlated with baseline serum HBsAg and HBeAg levels and might predict a shorter interval to HBeAg loss and seroconversion during antiviral treatment
10.1016/j.meegid.2015.05.013 · 2015 · External reference
Sera of Individuals Chronically Infected with Hepatitis B Virus (HBV) Contain Diverse RNA Types Produced by HBV Replication or Derived from Integrated HBV DNA
10.1128/jvi.01950-22 · 2023 · External reference
Transcription of hepatitis B virus covalently closed circular DNA is regulated by CpG methylation during chronic infection
10.1371/journal.pone.0110442 · 2014 · External reference
RNAi-based treatment of chronically infected patients and chimpanzees reveals that integrated hepatitis B virus DNA is a source of HBsAg
10.1126/scitranslmed.aan0241 · 2017 · External reference
Development of an NGS-Based Estimation of Integrated HBV DNA in Liver Biopsies and Detection in Liquid Biopsies
2025 · External reference
Analysis of genomic-length HBV sequences to determine genotype and subgenotype reference sequences
10.1099/jgv.0.001387 · 2020 · External reference
Aligning sequence reads, clone sequences and assembly contigs with BWA-MEM
2013 · External reference
fgbio
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Illumina error profiles: resolving fine-scale variation in metagenomic sequencing data
10.1186/s12859-016-0976-y · 2016 · External reference
Integrative genomics viewer
10.1038/nbt.1754 · 2011 · External reference
Proteomic Analysis of Nuclear Hepatitis B Virus Relaxed Circular DNA-Associated Proteins Identifies UV-Damaged DNA Binding Protein as a Host Factor Involved in Covalently Closed Circular DNA Formation
10.1128/jvi.01360-21 · 2022 · External reference
The loss of hepatitis B virus receptor NTCP/SLC10A1 in human liver cancer cells is due to epigenetic silencing
10.1128/jvi.01187-24 · 2024 · External reference
The feasibility of establishing a hamster model for HBV infection: in vitro evidence
10.1128/mbio.02615-24 · 2024 · External reference
Screening of an epigenetic compound library identifies BRD4 as a potential antiviral target for hepatitis B virus covalently closed circular DNA transcription
10.1016/j.antiviral.2023.105552 · 2023 · External reference
Host 3’ flap endonuclease Mus81 plays a critical role in trimming the terminal redundancy of hepatitis B virus relaxed circular DNA during covalently closed circular DNA formation
10.1371/journal.ppat.1012918 · 2025 · External reference
Inducible expression of human hepatitis B virus (HBV) in stably transfected hepatoblastoma cells: a novel system for screening potential inhibitors of HBV replication
10.1128/aac.41.8.1715 · 1997 · External reference
Spinoculation Enhances HBV Infection in NTCP-Reconstituted Hepatocytes
2015 · External reference
Hepatitis B Virus Precore Protein p22 Inhibits Alpha Interferon Signaling by Blocking STAT Nuclear Translocation
10.1128/jvi.00196-19 · 2019 · External reference
Screening of an epigenetic compound library identifies BRD4 as a potential antiviral target for hepatitis B virus covalently closed circular DNA transcription
10.1016/j.antiviral.2023.105552 · 2023 · External reference
A southern blot assay for detection of hepatitis B virus covalently closed circular DNA from cell cultures
10.1007/978-1-62703-484-5_13 · 2013 · External reference
Identification of an Intermediate in Hepatitis B Virus Covalently Closed Circular (CCC) DNA Formation and Sensitive and Selective CCC DNA Detection
2017 · External reference
T5 Exonuclease Hydrolysis of Hepatitis B Virus Replicative Intermediates Allows Reliable Quantification and Fast Drug Efficacy Testing of Covalently Closed Circular DNA by PCR
2018 · External reference
Ultrafast one-pass FASTQ data preprocessing, quality control, and deduplication using fastp
10.1002/imt2.107 · 2023 · External reference
fastp: an ultra-fast all-in-one FASTQ preprocessor
10.1093/bioinformatics/bty560 · 2018 · External reference
Unresolved reference
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MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger Datasets
10.1093/molbev/msw054 · 2016 · External reference
Unresolved reference
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