Research graph
References from Transcriptional signatures of rapid protection from Sudan virus infection by a single dose of a vesicular stomatitis virus-based vaccine. Local targets link to admitted publications; unresolved targets remain external evidence.
ICTV Virus Taxonomy Profile: Filoviridae 2024
10.1099/jgv.0.001955 · 2024 · External reference
Unresolved reference
2024 · External reference
Unresolved reference
External reference
Vesicular stomatitis virus-based Ebola vaccines with improved cross-protective efficacy
2011 · External reference
Live attenuated recombinant vaccine protects nonhuman primates against Ebola and Marburg viruses
10.1038/nm1258 · 2005 · External reference
Species-specific immunogenicity and protective efficacy of a vesicular stomatitis virus-based Sudan virus vaccine: a challenge study in macaques
10.1016/s2666-5247(23)00001-0 · 2023 · External reference
Predictive and comparative analysis of Ebolavirus proteins
10.1080/15384101.2015.1068472 · 2015 · External reference
One-for-one or one-for-all? Considerations for filovirus vaccine development
10.1371/journal.pbio.3003142 · 2025 · External reference
Filovirus vaccines as a response paradigm for emerging infectious diseases
10.1038/s41541-024-00985-y · 2024 · External reference
A bivalent adenovirus-vectored vaccine induces a robust humoral response, but does not protect cynomolgus macaques against a lethal challenge with Sudan virus
10.1093/infdis/jiae056 · 2024 · External reference
Thermostable bivalent filovirus vaccine protects against severe and lethal Sudan ebolavirus and marburgvirus infection
10.1016/j.vaccine.2023.12.053 · 2024 · External reference
Fast-acting single-dose vesicular stomatitis virus-Sudan virus vaccine: a challenge study in macaques
10.1016/j.lanmic.2025.101244 · 2025 · External reference
A single-shot ChAd3 vaccine provides protection from intramuscular and aerosol Sudan virus exposure
2024 · External reference
Single dose of a VSV-based vaccine rapidly protects macaques from marburg virus disease
10.3389/fimmu.2021.774026 · 2021 · External reference
Antiviral innate responses induced by VSV-EBOV vaccination contribute to rapid protection
10.1128/mbio.00597-19 · 2019 · External reference
Single-dose VSV-based vaccine protects cynomolgus macaques from disease after Taï Forest virus infection
10.1080/22221751.2023.2239950 · 2023 · External reference
STEM: a tool for the analysis of short time series gene expression data
10.1186/1471-2105-7-191 · 2006 · External reference
Next maSigPro: updating maSigPro bioconductor package for RNA-seq time series
10.1093/bioinformatics/btu333 · 2014 · External reference
Robust enumeration of cell subsets from tissue expression profiles
10.1038/nmeth.3337 · 2015 · External reference
Profiling cell type abundance and expression in bulk tissues with CIBERSORTx
10.1007/978-1-0716-0301-7_7 · 2020 · External reference
Transcriptional profiling of immune responses in NHPs after low-dose, VSV-based vaccination against Marburg virus
10.1080/22221751.2023.2252513 · 2023 · External reference
Antibodies are necessary for rVSV/ZEBOV-GP-mediated protection against lethal Ebola virus challenge in nonhuman primates
10.1073/pnas.1209591110 · 2013 · External reference
Rapid protection of nonhuman primates against Marburg virus disease using a single low-dose VSV-based vaccine
10.1016/j.ebiom.2023.104463 · 2023 · External reference
Filovirus entry into cells - new insights
10.1016/j.coviro.2012.02.015 · 2012 · External reference
Cryo-EM structure of Sudan ebolavirus glycoprotein complexed with its human endosomal receptor NPC1
10.1038/s42003-025-07613-y · 2025 · External reference
Markedly elevated levels of interferon (IFN)-gamma, IFN-alpha, interleukin (IL)-2, IL-10, and tumor necrosis factor-alpha associated with fatal Ebola virus infection
10.1086/514283 · 1999 · External reference
The role of cytokines and chemokines in filovirus infection
10.3390/v7102892 · 2015 · External reference
Natural history of Sudan ebolavirus infection in rhesus and cynomolgus macaques
10.1080/22221751.2022.2086072 · 2022 · External reference
Ebola virus glycoprotein directly triggers T lymphocyte death despite of the lack of infection
10.1371/journal.ppat.1006397 · 2017 · External reference
Depletion of peripheral blood T lymphocytes and NK cells during the course of ebola hemorrhagic Fever in cynomolgus macaques
10.1089/vim.2004.17.390 · 2004 · External reference
Defective humoral responses and extensive intravascular apoptosis are associated with fatal outcome in Ebola virus-infected patients
10.1038/7422 · 1999 · External reference
Role of the phosphatidylserine receptor TIM-1 in enveloped-virus entry
10.1128/jvi.01025-13 · 2013 · External reference
Ebola virus binding to Tim-1 on T lymphocytes induces a cytokine storm
10.1128/mbio.00845-17 · 2017 · External reference
Tim-1 is essential for induction and maintenance of IL-10 in regulatory B cells and their regulation of tissue inflammation
10.4049/jimmunol.1402632 · 2015 · External reference
Human regulatory memory B cells defined by expression of TIM-1 and TIGIT are dysfunctional in multiple sclerosis
10.3389/fimmu.2024.1360219 · 2024 · External reference
Human TIM-1 associates with the TCR complex and up-regulates T cell activation signals
10.4049/jimmunol.178.7.4342 · 2007 · External reference
Heterogeneous CD3 expression levels in differing T cell subsets correlate with the in vivo anti-CD3-mediated T cell modulation
10.4049/jimmunol.1401551 · 2015 · External reference
Complement-mediated neutralisation identified in Ebola virus disease survivor plasma: implications for protection and pathogenesis
10.3389/fimmu.2022.857481 · 2022 · External reference
Antibody-dependent enhancement of Ebola virus infection by human antibodies isolated from survivors
10.1016/j.celrep.2018.07.035 · 2018 · External reference
NF-κB in monocytes and macrophages - an inflammatory master regulator in multitalented immune cells
10.3389/fimmu.2023.1134661 · 2023 · External reference
Immunobiology of Ebola and Lassa virus infections
10.1038/nri.2016.138 · 2017 · External reference
Complement-induced release of monocyte chemotactic protein-1 from human smooth muscle cells. A possible initiating event in atherosclerotic lesion formation
10.1161/01.atv.16.5.673 · 1996 · External reference
Macrophages and chemokines as mediators of angiogenesis
2013 · External reference
Infection and activation of monocytes by Marburg and Ebola viruses
10.1128/jvi.75.22.11025-11033.2001 · 2001 · External reference
The magnitude and timing of recalled immunity after breakthrough infection is shaped by SARS-CoV-2 variants
10.1016/j.immuni.2022.05.018 · 2022 · External reference
Vaccination against rapidly evolving pathogens and the entanglements of memory
10.1038/s41590-024-01970-2 · 2024 · External reference
Migration, maintenance and recall of memory T cells in peripheral tissues
10.1038/nri2496 · 2009 · External reference
T cell trafficking through lymphatic vessels
10.3389/fimmu.2016.00613 · 2016 · External reference
Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor
10.1073/pnas.0511161103 · 2006 · External reference
Quantitative contribution of IL2Rγ to the dynamic formation of IL2-IL2R complexes
10.1371/journal.pone.0155684 · 2016 · External reference
Interleukin-2-mediated CD4 T-cell activation correlates highly with effective serological and T-cell responses to SARS-CoV-2 vaccination in people living with HIV
10.1002/jmv.29820 · 2024 · External reference
Basic clinical and laboratory features of filoviral hemorrhagic fever
2011 · External reference
Role of red blood cells in clinically relevant bleeding tendencies and complications
10.1016/j.jtha.2023.05.009 · 2023 · External reference
Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications
10.1152/physrev.00011.2005 · 2006 · External reference
Structures of ABCB10, a human ATP-binding cassette transporter in apo- and nucleotide-bound states
10.1073/pnas.1217042110 · 2013 · External reference
Protection against marburg virus using a recombinant VSV-Vaccine depends on T and B cell activation
10.3389/fimmu.2018.03071 · 2019 · External reference
Human transcriptomic response to the VSV-Vectored Ebola Vaccine
10.3390/vaccines9020067 · 2021 · External reference
EBOLA VACCINE. VSV-EBOV rapidly protects macaques against infection with the 2014/15 Ebola virus outbreak strain
10.1126/science.aab3920 · 2015 · External reference
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
10.1093/bioinformatics/btp616 · 2010 · External reference
