Research graph
References from SUMOylation of pseudorabies virus thymidine kinase regulates its nuclear localization and facilitates neuronal replication and reactivation. Local targets link to admitted publications; unresolved targets remain external evidence.
Pseudorabies virus as a zoonosis: scientific and public health implications
10.1007/s11262-024-02122-2 · 2025 · External reference
Molecular biology of pseudorabies virus: impact on neurovirology and veterinary medicine
10.1128/mmbr.69.3.462-500.2005 · 2005 · External reference
KSHV-TK: thymidine kinase or tyrosine kinase?
10.15252/embj.201490843 · 2015 · External reference
Alpha-Herpesvirus Thymidine Kinase Genes Mediate Viral Virulence and Are Potential Therapeutic Targets
10.3389/fmicb.2019.00941 · 2019 · External reference
HSV-1 thymidine kinase promotes virulence and latency in the mouse
1983 · External reference
Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate
10.1073/pnas.86.12.4736 · 1989 · External reference
Role of herpes simplex virus thymidine kinase expression in viral pathogenesis and latency
10.1159/000150188 · 1991 · External reference
A study of the ability of a TK-negative and gI/gE-negative pseudorabies virus (PRV) mutant inoculated by different routes to protect pigs against PRV infection
2000 · External reference
Latency of a thymidine kinase-negative pseudorabies vaccine virus detected by the polymerase chain reaction
10.1007/bf01317195 · 1992 · External reference
A genome-wide screen of Epstein-Barr virus proteins that modulate host SUMOylation identifies a SUMO E3 ligase conserved in herpesviruses
10.1371/journal.ppat.1007176 · 2018 · External reference
SUMOylation in Viral Replication and Antiviral Defense
2022 · External reference
SUMOylation of the human cytomegalovirus 72-kilodalton IE1 protein facilitates expression of the 86-kilodalton IE2 protein and promotes viral replication
10.1128/jvi.78.14.7803-7812.2004 · 2004 · External reference
Binding STAT2 by the acidic domain of human cytomegalovirus IE1 promotes viral growth and is negatively regulated by SUMO
10.1128/jvi.00833-08 · 2008 · External reference
Viral RNA-binding ability conferred by SUMOylation at PB1 K612 of influenza A virus is essential for viral pathogenesis and transmission
2021 · External reference
NS5 Sumoylation Directs Nuclear Responses That Permit Zika Virus To Persistently Infect Human Brain Microvascular Endothelial Cells
10.1128/jvi.01086-20 · 2020 · External reference
Role of SUMOylation in Human Oncogenic Herpesvirus Infection
10.1016/j.virusres.2020.197962 · 2020 · External reference
A viral ubiquitin ligase has substrate preferential SUMO targeted ubiquitin ligase activity that counteracts intrinsic antiviral defence
10.1371/journal.ppat.1002245 · 2011 · External reference
Kaposi’s sarcoma-associated herpesvirus K-bZIP represses gene transcription via SUMO modification
10.1128/jvi.79.15.9912-9925.2005 · 2005 · External reference
Sumoylation of the Epstein-Barr virus BZLF1 protein inhibits its transcriptional activity and is regulated by the virus-encoded protein kinase
10.1128/jvi.02369-09 · 2010 · External reference
Epstein-barr virus immediate-early protein BZLF1 is SUMO-1 modified and disrupts promyelocytic leukemia bodies
10.1128/jvi.75.5.2388-2399.2001 · 2001 · External reference
Human Oncogenic Herpesvirus and Post-translational Modifications - Phosphorylation and SUMOylation
2016 · External reference
Viruses, SUMO, and immunity: the interplay between viruses and the host SUMOylation system
10.1007/s13365-021-00995-9 · 2021 · External reference
Viral Interplay with the Host Sumoylation System
10.1007/978-3-319-50044-7_21 · 2017 · External reference
Post-Translational Modifications of Kaposi’s Sarcoma-Associated Herpesvirus Regulatory Proteins - SUMO and KSHV
10.3389/fmicb.2012.00031 · 2012 · External reference
Ubiquitin-related modifier SUMO1 and nucleocytoplasmic transport
10.1034/j.1600-0854.2002.30601.x · 2002 · External reference
Sumoylation: a regulatory protein modification in health and disease
10.1146/annurev-biochem-061909-093311 · 2013 · External reference
The nucleoporin RanBP2 has SUMO1 E3 ligase activity
10.1016/s0092-8674(01)00633-x · 2002 · External reference
TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence
10.1038/s41467-023-44502-6 · 2024 · External reference
Regulation of the nucleocytoplasmic trafficking of viral and cellular proteins by ubiquitin and SUMO
10.1111/boc.201100105 · 2012 · External reference
Site-specific SUMOylation of viral polymerase processivity factor localizes to ND10 subnuclear domains
10.1080/21505594.2021.2000689 · 2021 · External reference
Viral DNA Binding Protein SUMOylation Promotes PML Nuclear Body Localization Next to Viral Replication Centers
10.1128/mbio.00049-20 · 2020 · External reference
Effect of SUMO-SIM interaction on ICP0-mediated degradation of PML isoform II
2020 · External reference
Targeting of adenovirus proteins to PML bodies
10.1083/jcb.131.1.45 · 1995 · External reference
A simple and rapid approach to manipulate pseudorabies virus genome by CRISPR/Cas9 system
10.1007/s10529-015-1796-2 · 2015 · External reference
Unresolved reference
2001 · External reference
The ribosomal protein S26 regulates p53 activity in response to DNA damage
10.1038/onc.2013.170 · 2014 · External reference
Establishment of an In Vitro Model of Pseudorabies Virus Latency and Reactivation and Identification of Key Viral Latency-Associated Genes
10.3390/v15030808 · 2023 · External reference
