Research graph
References from Sex differences in hepatitis A virus infection in mice. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
2023 · External reference
Fulminant hepatitis A virus infection in the United States: Incidence, prognosis, and outcomes
10.1002/hep.21439 · 2006 · External reference
Type A viral hepatitis: A summary and update on the molecular virology, epidemiology, pathogenesis and prevention
2017 · External reference
Hepatitis A person-to-person outbreaks: Epidemiology, morbidity burden, and factors associated with hospitalization-multiple states, 2016-2019
10.1093/infdis/jiaa636 · 2021 · External reference
Factors associated with hepatitis A mortality during person-to-person outbreaks: A matched case-control study-United States, 2016-2019
10.1002/hep.31645 · 2021 · External reference
Preventable deaths during widespread community hepatitis A outbreaks - United States, 2016-2022
10.15585/mmwr.mm7242a1 · 2023 · External reference
Sex differences in hepatitis A incidence rates-a multi-year pooled-analysis based on national data from nine high-income countries
10.1371/journal.pone.0287008 · 2023 · External reference
Hospitalization and mortality due to hepatitis A in Taiwan: a 15-year nationwide cohort study
10.1111/jvh.12564 · 2016 · External reference
The changing gender differences in hepatitis a incidence in South Korea
10.1016/j.vaccine.2019.11.048 · 2020 · External reference
Change in hepatitis A epidemiology after vaccinating high risk children in Taiwan, 1995-2008
10.1016/j.vaccine.2011.02.001 · 2011 · External reference
Changing epidemiological characteristics of hepatitis A in Zhejiang Province, China: Increased susceptibility in adults
10.1371/journal.pone.0153804 · 2016 · External reference
MAVS-dependent host species range and pathogenicity of human hepatitis A virus
10.1126/science.aaf8325 · 2016 · External reference
Murine models of Hepatitis A virus infection
10.1101/cshperspect.a031674 · 2019 · External reference
T cells protect against hepatitis A virus infection and limit infection-induced liver injury
10.1016/j.jhep.2021.07.019 · 2021 · External reference
IRF3-mediated pathogenicity in a murine model of human hepatitis A
2021 · External reference
Hepato-selective dihydroquinolizinones active against hepatitis A virus in vitro and in vivo
10.1016/j.antiviral.2025.106145 · 2025 · External reference
Iminosugar glucosidase inhibitors reduce hepatic inflammation in hepatitis A virus-infected Ifnar1(-/-) mice
10.1128/jvi.00058-21 · 2021 · External reference
The ZCCHC14/TENT4 complex is required for hepatitis A virus RNA synthesis
2022 · External reference
Noncanonical Poly(A) Polymerase TENT4 drives expression of subgenomic hepatitis A Virus RNAs in infected cells
10.3390/v17050665 · 2025 · External reference
Viral protease cleavage of MAVS in genetically modified mice with hepatitis A virus infection
10.1016/j.jhep.2022.09.013 · 2023 · External reference
Biliary secretion of quasi-enveloped human hepatitis A virus
10.1128/mbio.01998-16 · 2016 · External reference
IRF3-mediated pathogenicity in a murine model of human hepatitis A
2021 · External reference
Viral Hepatitis and Liver Disease.
1984 · External reference
Sex differences in immunity to viral infections
10.3389/fimmu.2021.720952 · 2021 · External reference
Sex hormone signaling and regulation of immune function
10.1016/j.immuni.2023.10.008 · 2023 · External reference
Hepatic immune regulation and sex disparities
10.1038/s41575-024-00974-5 · 2024 · External reference
Modulatory effects of sex steroid hormones on brain-derived neurotrophic factor-tyrosine kinase B expression during adolescent development in C57Bl/6 mice
10.1111/j.1365-2826.2012.02277.x · 2012 · External reference
Comparing postnatal development of gonadal hormones and associated social behaviors in rats, mice, and humans
10.1210/en.2018-00220 · 2018 · External reference
Sex-biased gene expression across mammalian organ development and evolution
10.1126/science.adf1046 · 2023 · External reference
What have we learned about GPER function in physiology and disease from knockout mice?
10.1016/j.jsbmb.2015.06.014 · 2015 · External reference
G protein-coupled estrogen receptor in immune cells and its role in immune-related diseases
10.3389/fendo.2020.579420 · 2020 · External reference
Disruption of ESR1 alters the expression of genes regulating hepatic lipid and carbohydrate metabolism in male rats
10.1016/j.mce.2019.04.005 · 2019 · External reference
Estrogen receptor-α suppresses liver carcinogenesis and establishes sex-specific gene expression
10.3390/cancers13102355 · 2021 · External reference
Hepatic estrogen receptor α is critical for regulation of gluconeogenesis and lipid metabolism in males
10.1038/s41598-017-01937-4 · 2017 · External reference
The role of G Protein-Coupled Estrogen Receptor (GPER) in Vascular pathology and physiology
10.3390/biom13091410 · 2023 · External reference
Does GPER really function as a g protein-coupled estrogen receptor in vivo?
10.3389/fendo.2020.00148 · 2020 · External reference
Estrogen deficiency promotes hepatic steatosis via a glucocorticoid receptor-dependent mechanism in mice
10.1016/j.celrep.2018.02.041 · 2018 · External reference
Optimization of tamoxifen-induced Cre activity and its effect on immune cell populations
10.1038/s41598-020-72179-0 · 2020 · External reference
Insufficient antibody validation challenges oestrogen receptor beta research
10.1038/ncomms15840 · 2017 · External reference
Protocol for ovariectomy and estradiol replacement in mice
10.1016/j.xpro.2024.102910 · 2024 · External reference
The major pre- and postmenopausal estrogens play opposing roles in obesity-driven mammary inflammation and breast cancer development
10.1016/j.cmet.2020.05.008 · 2020 · External reference
Estrogens protect male mice from obesity complications and influence glucocorticoid metabolism
10.1038/ijo.2015.102 · 2015 · External reference
Estrogens stimulate serotonin neurons to inhibit binge-like eating in mice
10.1172/jci74726 · 2014 · External reference
Methods for long-term 17β-estradiol administration to mice
10.1016/j.ygcen.2011.11.014 · 2012 · External reference
Low-dose estrogen therapy ameliorates experimental autoimmune encephalomyelitis in two different inbred mouse strains
10.4049/jimmunol.166.3.2080 · 2001 · External reference
17beta-estradiol alters the activity of conventional and IFN-producing killer dendritic cells
10.4049/jimmunol.180.3.1423 · 2008 · External reference
Age-associated changes in the impact of sex steroids on influenza vaccine responses in males and females
10.1038/s41541-019-0124-6 · 2019 · External reference
Administration of 17β-estradiol to ovariectomized obese female mice reverses obesity-hypertension through an ACE2-dependent mechanism
10.1152/ajpendo.00030.2015 · 2015 · External reference
Measurement of a comprehensive sex steroid profile in rodent serum by high-sensitive gas chromatography-tandem mass spectrometry
10.1210/en.2014-1890 · 2015 · External reference
Mimicking women’s endocrine milieu in mice for women’s health-related studies
10.1038/s44294-025-00060-4 · 2025 · External reference
Metabolic impact of sex hormones on obesity
10.1016/j.brainres.2010.04.056 · 2010 · External reference
Increased adipose tissue aromatase activity improves insulin sensitivity and reduces adipose tissue inflammation in male mice
10.1152/ajpendo.00093.2017 · 2017 · External reference
Sex differences in the Toll-like receptor-mediated response of plasmacytoid dendritic cells to HIV-1
10.1038/nm.2004 · 2009 · External reference
Biological sex affects vaccine efficacy and protection against influenza in mice
10.1073/pnas.1805268115 · 2018 · External reference
G protein-coupled estrogen receptor 1 ameliorates nonalcoholic steatohepatitis through targeting AMPK-dependent signaling
10.1016/j.jbc.2024.105661 · 2024 · External reference
Kaempferol-induced GPER upregulation attenuates atherosclerosis via the PI3K/AKT/Nrf2 pathway
2021 · External reference
The sex steroid precursor dehydroepiandrosterone prevents nonalcoholic steatohepatitis by activating the AMPK pathway mediated by GPR30
10.1016/j.redox.2021.102187 · 2021 · External reference
New developments in AMPK and mTORC1 cross-talk
10.1042/ebc20240007 · 2024 · External reference
Basal expression of interferon regulatory factor 1 drives intrinsic hepatocyte resistance to multiple RNA viruses
10.1038/s41564-019-0425-6 · 2019 · External reference
Hepatovirus translation requires PDGFA-associated protein 1, an eIF4E-binding protein regulating endoplasmic reticulum stress responses
10.1126/sciadv.adq6342 · 2024 · External reference
Modulation of innate immune response to viruses including SARS-CoV-2 by progesterone
10.1038/s41392-022-00981-5 · 2022 · External reference
The ovary-liver axis: Molecular science and epidemiology
10.3390/ijms26136382 · 2025 · External reference
Sex hormones and their receptors regulate liver energy homeostasis
10.1155/2015/294278 · 2015 · External reference
Sex differences in lipid and lipoprotein metabolism
10.1016/j.molmet.2018.05.008 · 2018 · External reference
Hepatoviruses promote very-long-chain fatty acid and sphingolipid synthesis for viral RNA replication and quasi-enveloped virus release
10.1126/sciadv.adj4198 · 2023 · External reference
Gangliosides are essential endosomal receptors for quasi-enveloped and naked hepatitis A virus
10.1038/s41564-020-0727-8 · 2020 · External reference
Long-term immunogenicity of an inactivated virosome hepatitis A vaccine
10.1002/jmv.10244 · 2002 · External reference
Antibody persistence and immune memory elicited by combined hepatitis A and B vaccination in older adults
10.1016/j.vaccine.2006.10.024 · 2007 · External reference
Persistence of seropositivity among persons vaccinated for hepatitis A during infancy by maternal antibody status: 15-year follow-up
10.1002/hep.28375 · 2016 · External reference
Long-term antibody persistence in children after vaccination with the pediatric formulation of an aluminum-free virosomal hepatitis A vaccine
10.1097/inf.0000000000000616 · 2015 · External reference
Natural history, clinical manifestations, and pathogenesis of hepatitis A
2018 · External reference
Innate-like cytotoxic function of bystander-activated CD8+ T cells is associated with liver injury in acute hepatitis A
2018 · External reference
Redefining the immune landscape of hepatitis A virus infection
10.1038/s12276-025-01431-2 · 2025 · External reference
17β-Estradiol protects the liver against cold ischemia/reperfusion injury through the AKT kinase pathway
10.1016/j.jss.2012.07.007 · 2012 · External reference
17β-estradiol attenuates reduced-size hepatic ischemia/reperfusion injury by inhibition apoptosis via mitochondrial pathway in rats
10.1097/shk.0b013e31823f1918 · 2012 · External reference
Estrogen alleviates hepatocyte necroptosis depending on GPER in hepatic ischemia reperfusion injury
10.1007/s13105-021-00846-5 · 2022 · External reference
Estradiol-17beta protects against hypoxia-induced hepatocyte injury through ER-mediated upregulation of Bcl-2 as well as ER-independent antioxidant effects
10.1038/cr.2008.42 · 2008 · External reference
Effect of estrogens on the interferon-gamma producing cell population of mouse splenocytes
10.1271/bbb.70.47 · 2006 · External reference
Modulation of 17beta-estradiol on the number and cytotoxicity of NK cells in vivo related to MCM and activating receptors
10.1016/j.intimp.2007.09.017 · 2007 · External reference
Natural killer cells and IFN-γ protect against liver injury during HAV infection in mice
10.1128/jvi.01395-25 · 2025 · External reference
Functional role of type I and type II interferons in antiviral defense
10.1126/science.8009221 · 1994 · External reference
Host species-specific mutations in the thumb domain of the 3Dpol polymerase are required for efficient replication of human hepatitis A virus in mice
10.1371/journal.ppat.1014213 · 2026 · External reference
When estrogen deficiency meets immune responses induced by rabies vaccination
10.1128/spectrum.02726-24 · 2025 · External reference
Suppressed estrogen supply via extra-ovarian progesterone receptor membrane component 1 in menopause
10.7555/jbr.35.20200172 · 2021 · External reference