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(18)FDG PET imaging can quantify increased cellular metabolism in pulmonary arterial hypertension: a proof-of-principle study

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Oxygen sensing, homeostasis, and disease

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Hypoxia-inducible factors in human pulmonary arterial hypertension: a link to the intrinsic myeloid abnormalities

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Alterations of cellular bioenergetics in pulmonary artery endothelial cells

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Hypoxia inducible-factor1alpha regulates the metabolic shift of pulmonary hypertensive endothelial cells

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Glycolytic metabolism in hearts of pulmonary arterial hypertension patients [abstract]

2012 · External reference

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Circulating angiogenic precursors in idiopathic pulmonary arterial hypertension

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Relation between right ventricular function and increased right ventricular [18F]fluorodeoxyglucose accumulation in patients with heart failure

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Different mechanisms for changes in glucose uptake of the right and left ventricular myocardium in pulmonary hypertension

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Right ventricular failure in idiopathic pulmonary arterial hypertension is associated with inefficient myocardial oxygen utilization

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PET imaging may provide a novel biomarker and understanding of right ventricular dysfunction in patients with idiopathic pulmonary arterial hypertension

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Lung 18F-fluorodeoxyglucose positron emission tomography for diagnosis and monitoring of pulmonary arterial hypertension

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Chronic pulmonary artery pressure elevation is insufficient to explain right heart failure

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Comparison of baseline predictors of prognosis in pulmonary arterial hypertension in patients surviving <2 years and those surviving >5 years after baseline right-sided cardiac catheterization

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Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1alpha-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer

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An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension

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Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension: a basis for excessive cell proliferation and a new therapeutic target

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Role for miR-204 in human pulmonary arterial hypertension

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Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotaline

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Altered microRNA processing in heritable pulmonary arterial hypertension: an important role for Smad-8

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Downregulation of miR-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes

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Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis

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miR-20b modulates VEGF expression by targeting HIF-1 alpha and STAT3 in MCF-7 breast cancer cells

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Identification of hypoxia-inducible factor-1 alpha as a novel target for miR-17–92 microRNA cluster

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miR-31 ablates expression of the HIF regulatory factor FIH to activate the HIF pathway in head and neck carcinoma

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MicroRNA-519c suppresses hypoxia-inducible factor-1 alpha expression and tumor angiogenesis

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Impaired mitochondrial biogenesis precedes heart failure in right ventricular hypertrophy in congenital heart disease

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Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1alpha

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Hypoxia-inducible factor-dependent degeneration, failure, and malignant transformation of the heart in the absence of the von Hippel-Lindau protein

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