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References from Performance of the EXAcerbations of Chronic Pulmonary Disease Tool Patient-reported Outcome Measure in Three Clinical Trials of Chronic Obstructive Pulmonary Disease. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
2011 · External reference
Unresolved reference
2009 · External reference
Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease
10.1136/thorax.57.10.847 · 2002 · External reference
COPD: epidemiology, prevalence, morbidity and mortality, and disease heterogeneity
10.1378/chest.121.5_suppl.121s · 2002 · External reference
Impact of chronic obstructive pulmonary disease on quality of life: the role of dyspnea
10.1016/j.amjmed.2006.08.003 · 2006 · External reference
Health status deterioration in patients with chronic obstructive pulmonary disease
10.1164/ajrccm.163.1.2005009 · 2001 · External reference
Factors that influence disease-specific quality of life or health status in patients with COPD: a review and meta-analysis of Pearson correlations
10.4104/pcrj.2011.00029 · 2011 · External reference
Global burden of COPD: risk factors, prevalence, and future trends
10.1016/s0140-6736(07)61380-4 · 2007 · External reference
Projections of global mortality and burden of disease from 2002 to 2030
10.1371/journal.pmed.0030442 · 2006 · External reference
Clinical predictors of exacerbation frequency in chronic obstructive pulmonary disease
10.1111/j.1752-699x.2010.00234.x · 2011 · External reference
Frequent exacerbations of chronic obstructive pulmonary disease—a distinct phenotype?
10.1056/nejme1008184 · 2010 · External reference
Relationship between respiratory symptoms and medical treatment in exacerbations of COPD
10.1183/09031936.05.00143404 · 2005 · External reference
Toward a consensus definition for COPD exacerbations
10.1378/chest.117.5_suppl_2.398s · 2000 · External reference
Underreporting exacerbation of chronic obstructive pulmonary disease in a longitudinal cohort
10.1164/rccm.200708-1290oc · 2008 · External reference
Effect of exacerbation on quality of life in patients with chronic obstructive pulmonary disease
10.1164/ajrccm.157.5.9709032 · 1998 · External reference
Negative impacts of unreported COPD exacerbations on health-related quality of life at 1 year
10.1183/09031936.00079409 · 2010 · External reference
Antibiotic therapy in exacerbations of chronic obstructive pulmonary disease
10.7326/0003-4819-106-2-196 · 1987 · External reference
Time course and pattern of COPD exacerbation onset
10.1136/thoraxjnl-2011-200768 · 2012 · External reference
Predictive accuracy of patient-reported exacerbation frequency in COPD
10.1183/09031936.00035909 · 2011 · External reference
Unresolved reference
External reference
Guidance for industry on patient-reported outcome measures: use in medical product development to support labeling claims
2009 · External reference
Draft guidance for industry on chronic obstructive pulmonary disease: developing drugs for treatment
2007 · External reference
Guidance for industry on acute bacterial exacerbations of chronic bronchitis in patients with chronic obstructive pulmonary disease: developing antimicrobial drugs for treatment
2012 · External reference
Characterizing and quantifying the symptomatic features of COPD exacerbations
10.1378/chest.10-1240 · 2011 · External reference
Patient-reported outcome (PRO) measures for clinical trials of COPD: the EXACT and E-RS
10.3109/15412555.2013.795423 · 2013 · External reference
Development of the EXAcerbations of Chronic Obstructive Pulmonary Disease Tool (EXACT): a patient-reported outcome (PRO) measure
10.1111/j.1524-4733.2010.00772.x · 2010 · External reference
Standardizing measurement of chronic obstructive pulmonary disease exacerbations: reliability and validity of a patient-reported diary
10.1164/rccm.201005-0762oc · 2011 · External reference
Content validity—establishing and reporting the evidence in newly developed patient-reported outcomes (PRO) instruments for medical product evaluation: ISPOR PRO good research practices task force report: part 1—eliciting concepts for a new PRO instrument
10.1016/j.jval.2011.06.014 · 2011 · External reference
Content validity—establishing and reporting the evidence in newly developed patient-reported outcomes (PRO) instruments for medical product evaluation: ISPOR PRO Good Research Practices Task Force report: part 2—assessing respondent understanding
10.1016/j.jval.2011.06.013 · 2011 · External reference
A randomised, placebo-controlled, dose-finding study of AZD9668, an oral inhibitor of neutrophil elastase, in patients with chronic obstructive pulmonary disease treated with tiotropium
10.3109/15412555.2011.641803 · 2012 · External reference
AZD9668, a neutrophil elastase inhibitor, plus ongoing budesonide/formoterol in patients with COPD
10.1016/j.rmed.2011.10.020 · 2012 · External reference
The breathlessness, cough, and sputum scale: the development of empirically based guidelines for interpretation
10.1378/chest.124.6.2182 · 2003 · External reference
Unresolved reference
2003 · External reference
A self-complete measure of health status for chronic airflow limitation: the St. George’s Respiratory Questionnaire
10.1164/ajrccm/145.6.1321 · 1992 · External reference
Development and validation of an improved, COPD-specific version of the St. George Respiratory Questionnaire
10.1378/chest.06-0702 · 2007 · External reference
Impact on patients’ health status following early identification of a COPD exacerbation
10.1183/09031936.00166606 · 2007 · External reference
Once-daily bronchodilators for chronic obstructive pulmonary disease: indacaterol versus tiotropium
10.1164/rccm.200910-1500oc · 2010 · External reference
Effect of 6 months of erythromycin treatment on inflammatory cells in induced sputum and exacerbations in chronic obstructive pulmonary disease
10.1159/000321374 · 2010 · External reference
Defining COPD exacerbations: impact on estimation of incidence and burden in primary care
10.1016/j.pcrj.2006.08.009 · 2006 · External reference
A longitudinal study evaluating the effect of exacerbations on physical activity in patients with chronic obstructive pulmonary disease
10.1513/annalsats.201304-100oc · 2013 · External reference
Unresolved reference
2011 · External reference
Patient’s perception of exacerbations of COPD—the PERCEIVE study
10.1016/j.rmed.2006.07.010 · 2007 · External reference
Time course and recovery of exacerbations in patients with chronic obstructive pulmonary disease
10.1164/ajrccm.161.5.9908022 · 2000 · External reference
Exacerbations of chronic obstructive pulmonary disease—a patients’ perspective
10.1016/j.pcrj.2006.01.003 · 2006 · External reference
Impact of exacerbations on COPD
10.1183/09059180.00002610 · 2010 · External reference
Impact of frequency of COPD exacerbations on pulmonary function, health status and clinical outcomes
2009 · External reference
Exacerbations of COPD: quantifying the patient’s perspective using discrete choice modelling
10.1183/09031936.05.00142704 · 2005 · External reference
Patient understanding, detection, and experience of COPD exacerbations: an observational, interview-based study
10.1378/chest.130.1.133 · 2006 · External reference
Effect of exacerbations on quality of life in patients with chronic obstructive pulmonary disease: a 2 year follow up study
10.1136/thx.2003.008730 · 2004 · External reference