Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Research graph
References from COL4A3 promotes invasion and acts as a biomarker in pituitary neuroendocrine tumor. Local targets link to admitted publications; unresolved targets remain external evidence.
Pituitary-tumor endocrinopathies
10.1056/nejmra1810772 · 2020 · External reference
The epidemiology of aggressive pituitary tumors (and its challenges)
10.1007/s11154-020-09556-7 · 2020 · External reference
Aggressive pituitary tumors (PitNETs)
10.1507/endocrj.ej23-0007 · 2023 · External reference
Overview of omics biomarkers in pituitary neuroendocrine tumors to design future diagnosis and treatment strategies
10.1007/s13167-021-00246-1 · 2021 · External reference
The microenvironment of pituitary adenomas: biological, clinical and therapeutical implications
10.1007/s11102-022-01211-5 · 2022 · External reference
Clinical biology of the pituitary adenoma
10.1210/endrev/bnac010 · 2022 · External reference
Collagen architecture and signaling orchestrate cancer development
10.1016/j.trecan.2023.06.002 · 2023 · External reference
The role of network-forming collagens in cancer progression
10.1002/ijc.34004 · 2022 · External reference
COL4A3 expression correlates with pathogenesis, pathologic behaviors, and prognosis of gastric carcinomas
10.1016/j.humpath.2011.10.028 · 2013 · External reference
The invasion mode of GH(3) cells is conditioned by collagen subtype, and its efficiency depends on cell-cell adhesion
10.1016/j.abb.2012.08.011 · 2012 · External reference
Extracellular matrix components regulate ACTH production and proliferation in corticotroph tumor cells
10.1016/s0303-7207(01)00390-2 · 2001 · External reference
COL6A6 interacted with P4HA3 to suppress the growth and metastasis of pituitary adenoma via blocking PI3K-Akt pathway
10.18632/aging.102300 · 2019 · External reference
The collagen landscape in cancer: profiling collagens in tumors and in circulation reveals novel markers of cancer-associated fibroblast subtypes
10.1002/path.6207 · 2024 · External reference
HISAT: a fast spliced aligner with low memory requirements
10.1038/nmeth.3317 · 2015 · External reference
HTSeq – a python framework to work with high-throughput sequencing data
10.1093/bioinformatics/btu638 · 2015 · External reference
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
10.1186/s13059-014-0550-8 · 2014 · External reference
Quantification of histochemical staining by color deconvolution
2001 · External reference
Semi-quantitative determination of protein expression using immunohistochemistry staining and analysis: an integrated protocol
10.21769/bioprotoc.3465 · 2019 · External reference
Type IV collagen stimulates pancreatic cancer cell proliferation, migration, and inhibits apoptosis through an autocrine loop
10.1186/1471-2407-13-154 · 2013 · External reference
Type IV collagen alpha5 chain promotes luminal breast cancer progression through c-Myc-driven glycolysis
10.1093/jmcb/mjac068 · 2023 · External reference
Type IV collagen immunostaining is a simple, reliable diagnostic tool for distinguishing between adenomatous and normal pituitary glands
10.5858/2007-131-931-ticiia · 2007 · External reference
Collagen in pituitary adenomas: a comprehensive review of biological roles and clinical implications
2025 · External reference
Hypoxia-induced downregulation of miR-29 in renal tumor cells affects collagen IV subunit expression through multiple sites
10.3390/biomedicines10123286 · 2022 · External reference
Reduction of type IV collagen by upregulated miR-29 in normal elderly mouse and klotho-deficient, senescence-model mouse
10.1371/journal.pone.0048974 · 2012 · External reference
Consensus statement on standards and guidelines for the molecular diagnostics of Alport syndrome: refining the ACMG criteria
10.1038/s41431-021-00858-1 · 2021 · External reference
A founder COL4A3 pathogenic variant resulting in Alport syndrome and thin basement membrane disease: a case report series
10.3389/fmed.2023.1281049 · 2023 · External reference
Transcriptome-derived ligand-receptor interactome of major PitNET subgroups
10.1055/a-2088-6594 · 2024 · External reference
The role of activation of PI3K/AKT/mTOR and RAF/MEK/ERK pathways in aggressive pituitary adenomas-new potential therapeutic approach-a systematic review
10.3390/ijms241310952 · 2023 · External reference
Collagen facilitates the colorectal cancer stemness and metastasis through an integrin/PI3K/AKT/Snail signaling pathway
10.1016/j.biopha.2019.108708 · 2019 · External reference
Serum endostatin levels are elevated and correlate with serum vascular endothelial growth factor levels in patients with pituitary adenomas
10.1007/s11102-005-5258-z · 2005 · External reference
Type IV collagen as a potential biomarker of metastatic breast cancer
10.1007/s10585-021-10082-2 · 2021 · External reference
The prognostic and predictive value of soluble type IV collagen in colorectal cancer: a retrospective multicenter study
10.1158/1078-0432.ccr-15-2342 · 2016 · External reference
Type IV collagen is a tumour stroma-derived biomarker for pancreas cancer
10.1038/sj.bjc.6605107 · 2009 · External reference
The evolving tumor microenvironment: from cancer initiation to metastatic outgrowth
10.1016/j.ccell.2023.02.016 · 2023 · External reference
The role of the tumour microenvironment in the angiogenesis of pituitary tumours
10.1007/s12020-020-02478-z · 2020 · External reference
The good and the bad collagens of fibrosis – their role in signaling and organ function
10.1016/j.addr.2017.07.014 · 2017 · External reference
Antigenicity and immunogenicity of collagen
10.1002/jbm.b.30096 · 2004 · External reference
The pituitary tumour-transforming gene 1/delta-like homologue 1 pathway plays a key role in liver fibrogenesis
10.1111/liv.15165 · 2022 · External reference
Comparison of serum 7S fragment of type IV collagen and serum central triple-helix of type IV collagen for assessment of liver fibrosis in patients with chronic viral liver disease
10.1016/s0168-8278(96)80023-7 · 1996 · External reference
Parallel trajectories in the discovery of the SCN-OVLT and pituitary portal pathways: legacies of Geoffrey Harris
10.1111/jne.13245 · 2023 · External reference
A new prognostic clinicopathological classification of pituitary adenomas: a multicentric case-control study of 410 patients with 8 years post-operative follow-up
10.1007/s00401-013-1084-y · 2013 · External reference