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References from Targeted Apc;Twist Double-Mutant Mice: A New Model of Spontaneous Osteosarcoma That Mimics the Human Disease. Local targets link to admitted publications; unresolved targets remain external evidence.
Genetic alterations in primary osteosarcoma from 54 children and adolescents by targeted allelotyping
10.1038/sj.bjc.6600968 · 2003 · External reference
Frequent genomic abnormalities at TWIST in human pediatric osteosarcomas
10.1002/ijc.21068 · 2005 · External reference
Involvement of MET/TWIST/APC combination or the potential role of ossification factors in pediatric high-grade osteosarcoma oncogenesis
10.1593/neo.07367 · 2007 · External reference
C-fos-induced osteosarcoma formation in transgenic mice: cooperativity with c-jun and the role of endogenous c-fos
1995 · External reference
Control of cell cycle gene expression in bone development and during c-Fos-induced osteosarcoma formation
10.1002/(sici)1520-6408(1998)22:4<386::aid-dvg8>3.0.co;2-2 · 1998 · External reference
Conditional mouse osteosarcoma, dependant on p53 loss potentiated by loss of Rb, mimics the human disease
10.1101/gad.1656808 · 2008 · External reference
Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage
10.1073/pnas.0805462105 · 2008 · External reference
Commonly used mouse models of osteosarcoma
10.1016/j.critrevonc.2006.03.006 · 2006 · External reference
Human xenograft osteosarcoma models with spontaneous metastasis in mice: clinical relevance and applicability for drug testing
10.1007/s00432-006-0157-x · 2007 · External reference
Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome
10.1016/j.cell.2004.11.004 · 2004 · External reference
Spontaneous and irradiation-induced tumour susceptibility in BRCA2 germline mutant mice and cooperative effects with a p53 germline mutation
10.1080/01926230600611794 · 2006 · External reference
Dorso-ventral and rostro-caudal sequential expression of M-twist in the postimplantation murine embryo
10.1016/0925-4773(95)00369-x · 1995 · External reference
Mutations of the TWIST gene in the Saethre-Chotzen syndrome
10.1038/ng0197-42 · 1997 · External reference
The variable expressivity and incomplete penetrance of the twist-null heterozygous mouse phenotype resemble those of human Saethre-Chotzen syndrome
10.1093/hmg/7.6.945 · 1998 · External reference
Craniosynostosis in Twist heterozygous mice: a model for Saethre-Chotzen syndrome
10.1002/ar.10124 · 2002 · External reference
Twist is a potential oncogene that inhibits apoptosis
10.1101/gad.13.17.2207 · 1997 · External reference
Differential expression of the epithelial-mesenchymal transition regulators snail, SIP1, and twist in gastric cancer
10.1016/s0002-9440(10)64464-1 · 2002 · External reference
DNA methylation of RASSF1A, HIN-1, RAR-β, cyclin D2 and Twist in in situ and invasive lobular breast carcinoma
10.1002/ijc.11508 · 2003 · External reference
Oncogenic cooperation between H-Twist and N-Myc overrides failsafe programs in cancer cells
10.1016/j.ccr.2004.09.033 · 2004 · External reference
TWIST activation by hypoxia inducible factor-1 (HIF-1): implications in metastasis and development
10.4161/cc.7.14.6324 · 2008 · External reference
SFOP OS94: a randomised trial comparing preoperative high-dose methotrexate plus doxorubicin to high-dose methotrexate plus etoposide and ifosfamide in osteosarcoma patients
10.1016/j.ejca.2006.10.023 · 2007 · External reference
The adenomatous polyposis coli (APC) tumour suppressor
1997 · External reference
Wnt signalling: complexity at the surface
10.1242/jcs.02826 · 2006 · External reference
Induction of a β-catenin-LEF-1 complex by wnt-1 and transforming mutants of β-catenin
10.1038/sj.onc.1201462 · 1997 · External reference
WNT signalling in the normal intestine and colorectal cancer
10.2741/2076 · 2007 · External reference
Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression
10.1038/sj.onc.1207676 · 2004 · External reference
Lymphoid enhancer factor-1 and β-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter
10.1074/jbc.m211443200 · 2003 · External reference
TWIST inactivation reduces CBFA1/RUNX2 expression and DNA binding to the osteocalcin promoter in osteoblasts
10.1016/s0006-291x(02)02260-x · 2002 · External reference
Apc1638N: a mouse model for familial adenomatous polyposis-associated desmoid tumors and cutaneous cysts
10.1016/s0016-5085(98)70478-0 · 1998 · External reference
A targeted chain-termination mutation in the mouse Apc gene results in multiple intestinal tumors
10.1073/pnas.91.19.8969 · 1994 · External reference
Mechanisms of APC-driven tumorigenesis: lessons from mouse models
10.1159/000015361 · 1999 · External reference
Tumour-associated Apc mutations in Mlh1-/- Apc1638N mice reveal a mutational signature of Mlh1 deficiency
10.1038/sj.onc.1203962 · 2000 · External reference
A novel orthotopic murine model provides insights into cellular and molecular characteristics contributing to human osteosarcoma
10.1007/s10585-006-9046-6 · 2006 · External reference
Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma
10.1083/jcb.200409187 · 2004 · External reference
Twist is required for establishment of the mouse coronal suture
10.1111/j.1469-7580.2005.00411.x · 2005 · External reference
Bone tumour induction after incorporation of short-lived radionuclides
10.1007/bf01226625 · 1991 · External reference
Spontaneous fibro-osseous proliferative lesions in the sternums and femurs of B6C3F1 mice
10.1177/030098589102800505 · 2001 · External reference
Metastatic osteosarcoma at diagnosis: prognostic factors and long-term outcome, the French pediatric experience
10.1002/cncr.21263 · 2005 · External reference
Analysis of the presence of osteocalcin, S-100 protein, and proliferating cell nuclear antigen in cells of various types of osteosarcomas
1996 · External reference
Osteocalcin and osteonectin immunoreactivity in the diagnosis of osteosarcoma
10.1093/ajcp/108.4.464 · 1997 · External reference
Primary osteosarcoma of the head and neck in pediatric patients: a clinicopathologic study of 22 cases with a review of the literature
10.1002/1097-0142(20010201)91:3<598::aid-cncr1040>3.0.co;2-d · 2001 · External reference
Nuclear β-catenin in basal cell carcinoma correlates with increased proliferation
10.1111/j.1365-2133.2004.06048.x · 2004 · External reference
Adenomatous polyposis coli (APC), β-catenin, and cadherin are expressed in human bone and cartilage
10.1046/j.1365-2559.2001.01287.x · 2001 · External reference
Prognostic implication of immunohistochemical Runx2 expression in osteosarcoma
10.1177/030089160909500307 · 2009 · External reference
Craniofacial osteosarcomas: plain film, CT, and MR findings in 46 cases
10.2214/ajr.150.6.1397 · 1988 · External reference
Osteosarcoma of the head and neck region: lessons learned from a single-institution experience of 50 patients
10.1002/hed.20820 · 2008 · External reference
Relationships between plain-film radiographic patterns and clinicopathologic variables in AJCC stage II osteosarcoma
10.1007/s00256-008-0536-2 · 2008 · External reference
