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References from Monitoring Sunitinib-Induced Vascular Effects to Optimize Radiotherapy Combined with Soy Isoflavones in Murine Xenograft Tumor. Local targets link to admitted publications; unresolved targets remain external evidence.
Cancer statistics, 2010
2010 · External reference
Renal-cell carcinoma
10.1056/nejm199609193351207 · 1996 · External reference
Nephrectomy followed by interferon alfa-2b compared with interferon alfa-2b alone for metastatic renal-cell cancer
10.1056/nejmoa003013 · 2001 · External reference
Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy
10.1038/nm0901-987 · 2001 · External reference
Normalization of tumor vasculature: an emerging concept in antiangiogenic therapy
10.1126/science.1104819 · 2005 · External reference
The impact of tumor burden characteristics in patients with metastatic renal cell carcinoma treated with sunitinib
2010 · External reference
Renal cell carcinoma: ten years of significant advances
10.1007/s11523-010-0150-9 · 2010 · External reference
New strategies in kidney cancer: therapeutic advances through understanding the molecular basis of response and resistance
10.1158/1078-0432.ccr-09-2273 · 2010 · External reference
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
10.1056/nejmoa065044 · 2007 · External reference
Overall survival and updated results for sunitinib compared with interferon alfa in patients with metastatic renal cell carcinoma
10.1200/jco.2008.20.1293 · 2009 · External reference
Dynamic contrast-enhanced magnetic resonance imaging of vascular changes induced by sunitinib in papillary renal cell carcinoma xenograft tumors
10.1593/neo.09618 · 2009 · External reference
Dynamic contrast-enhanced magnetic resonance imaging of sunitinib-induced vascular changes to schedule chemotherapy in renal cell carcinoma xenograft tumors
10.1593/tlo.10136 · 2010 · External reference
In vivo antitumor activity of SU11248, a novel tyrosine kinase inhibitor targeting vascular endothelial growth factor and platelet-derived growth factor receptors: determination of a pharmacokinetic/pharmacodynamic relationship
2003 · External reference
SU11248 inhibits KIT and platelet-derived growth factor receptor beta in preclinical models of human small cell lung cancer
2003 · External reference
Axitinib—a selective inhibitor of the vascular endothelial growth factor (VEGF) receptor
10.1007/s11523-009-0126-9 · 2009 · External reference
Nonclinical antiangiogenesis and antitumor activities of axitinib (AG-013736), an oral, potent, and selective inhibitor of vascular endothelial growth factor receptor tyrosine kinases 1, 2, 3
10.1158/1078-0432.ccr-08-0652 · 2008 · External reference
Progression of renal cell carcinoma is inhibited by genistein and radiation in an orthotopic model
10.1186/1471-2407-7-4 · 2007 · External reference
Sunitinib acts primarily on tumor endothelium rather than tumor cells to inhibit the growth of renal cell carcinoma
10.1158/0008-5472.can-09-3722 · 2010 · External reference
Activity of SU11248, a multitargeted inhibitor of vascular endothelial growth factor receptor and plateletderived growth factor receptor, in patients with metastatic renal cell carcinoma
10.1200/jco.2005.02.2574 · 2006 · External reference
Cardiotoxicity associated with the cancer therapeutic agent sunitinib malate
10.1093/annonc/mdn168 · 2008 · External reference
Cardiac toxicity of sunitinib and sorafenib in patients with metastatic renal cell carcinoma
10.1200/jco.2007.15.6331 · 2008 · External reference
Genistein potentiates inhibition of tumor growth by radiation in a prostate cancer orthotopic model
10.1158/1535-7163.1271.3.10 · 2004 · External reference
Genistein inhibits radiation-induced activation of NF-κB in prostate cancer cells promoting apoptosis and G2/M cell cycle arrest
10.1186/1471-2407-6-107 · 2006 · External reference
Down-regulation of apurinic/apyrimidinic endonuclease 1/redox factor-1 expression by soy isoflavones enhances prostate cancer radiotherapy in vitro and in vivo
10.1158/0008-5472.can-06-2147 · 2007 · External reference
Soy isoflavones enhance radiotherapy in a metastatic prostate cancer model
10.1002/ijc.22548 · 2007 · External reference
Radiation-induced HIF-1α cell survival pathway is inhibited by soy isoflavones in prostate cancer cells
10.1002/ijc.24015 · 2009 · External reference
Daidzein effect on hormone refractory prostate cancer in vitro and in vivo compared to genistein and soy extract: potentiation of radiotherapy
10.1007/s11095-010-0107-9 · 2010 · External reference
An overview of the health effects of isoflavones with an emphasis on prostate cancer risk and prostate-specific antigen levels
10.1093/jaoac/89.4.1121 · 2006 · External reference
Soy isoflavones in conjunction with radiation therapy in patients with prostate cancer
10.1080/01635581.2010.509839 · 2010 · External reference
Vascular normalization by vascular endothelial growth factor receptor 2 blockade induces a pressure gradient across the vasculature and improves drug penetration in tumors
10.1158/0008-5472.can-04-0074 · 2004 · External reference
Dynamic contrast-enhanced magnetic resonance imaging as an imaging biomarker
10.1200/jco.2006.06.8080 · 2006 · External reference
Dietary isoflavones in the prevention of cardiovascular disease—a molecular perspective
10.1016/j.fct.2007.06.029 · 2008 · External reference
Simultaneous inhibition of the receptor kinase activity of vascular endothelial, fibroblast, and platelet-derived growth factors suppresses tumor growth and enhances tumor radiation response
2002 · External reference
Tumor response to ionizing radiation combined with antiangiogenesis or vascular targeting agents: exploring mechanisms of interaction
2003 · External reference
Targeting angiogenic processes by combination rofecoxib and ionizing radiation
10.1097/00000421-200110000-00005 · 2001 · External reference
Vascular endothelial growth factor receptor-2-blocking antibody potentiates radiation-induced long-term control of human tumor xenografts
2001 · External reference