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References from Expression of Telomeres in Astrocytoma WHO Grade 2 to 4: TERRA Level Correlates with Telomere Length, Telomerase Activity, and Advanced Clinical Grade. Local targets link to admitted publications; unresolved targets remain external evidence.
Sizing the ends: normal length of human telomeres
10.1016/j.aanat.2010.07.005 · 2010 · External reference
Telomere maintenance mechanisms and cellular immortalization
10.1016/s0959-437x(99)80014-8 · 1999 · External reference
The hallmarks of cancer
10.1016/s0092-8674(00)81683-9 · 2000 · External reference
Telomere maintenance and cancer—look, no telomerase
10.1038/nrc929 · 2002 · External reference
A survey of telomerase activity in human cancer
10.1016/s0959-8049(97)00062-2 · 1997 · External reference
Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging
10.1038/nm1006-1133 · 2006 · External reference
Medical genetics and epigenetics of telomerase
10.1111/j.1582-4934.2011.01276.x · 2011 · External reference
A robust assay for alternative lengthening of telomeres in tumors shows the significance of alternative lengthening of telomeres in sarcomas and astrocytomas
10.1158/1078-0432.217.11.1 · 2005 · External reference
Assaying and investigating alternative lengthening of telomeres activity in human cells and cancers
10.1016/j.febslet.2010.06.009 · 2010 · External reference
Telomere elongation in immortal human cells without detectable telomerase activity
10.1002/j.1460-2075.1995.tb00098.x · 1995 · External reference
Correlating telomerase activity levels with human neuroblastoma outcomes
10.1038/nm0395-249 · 1995 · External reference
The potential utility of telomere-related markers for cancer diagnosis
10.1111/j.1582-4934.2011.01284.x · 2011 · External reference
Telomerase: is it the future diagnostic and prognostic tool in human cancer?
10.1586/14737159.5.6.907 · 2005 · External reference
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
10.1056/nejmoa043330 · 2005 · External reference
Telomerase in brain tumors
10.1007/s00381-002-0562-7 · 2002 · External reference
Telomerase activity in human brain tumours
10.1016/s0140-6736(95)91865-5 · 1995 · External reference
Telomerase activity and hTERT mRNA expression in glial tumors
2006 · External reference
Association of mutant TP53 with alternative lengthening of telomeres and favorable prognosis in glioma
10.1158/0008-5472.can-06-0910 · 2006 · External reference
Alternative lengthening of telomeres and survival in patients with glioblastoma multiforme
10.1016/s0140-6736(03)12681-5 · 2003 · External reference
Presence of alternative lengthening of telomeres mechanism in patients with glioblastoma identifies a less aggressive tumor type with longer survival
10.1097/nen.0b013e3181e576cf · 2010 · External reference
Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends
10.1126/science.1147182 · 2007 · External reference
Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II
10.1038/ncb1685 · 2008 · External reference
CpG-island promoters drive transcription of human telomeres
10.1261/rna.1748309 · 2009 · External reference
The telomeric transcriptome and SMG proteins at the crossroads
10.1159/000167804 · 2008 · External reference
Telomerase activity is associated with an increase in DNA methylation at the proximal subtelomere and a reduction in telomeric transcription
10.1093/nar/gkn1030 · 2009 · External reference
Telomere measurement by quantitative PCR
10.1093/nar/30.10.e47 · 2002 · External reference
A quantitative real-time PCR method for absolute telomere length
10.2144/000112761 · 2008 · External reference
A small upstream open reading frame causes inhibition of human major vault protein expression from a ubiquitous mRNA splice variant
10.1016/s0014-5793(01)02318-3 · 2001 · External reference
High quality RNA isolation from tumours with low cellularity and high extracellular matrix component for cDNA microarrays: application to chondrosarcoma
10.1136/jcp.54.10.778 · 2001 · External reference
Specific association of human telomerase activity with immortal cells and cancer
10.1126/science.7605428 · 1994 · External reference
A new mathematical model for relative quantification in real-time RT-PCR
10.1093/nar/29.9.e45 · 2001 · External reference
Advances in quantification and characterization of telomerase activity by the telomeric repeat amplification protocol (TRAP)
10.1093/nar/25.13.2595 · 1997 · External reference
New cellular tools reveal complex epithelial-mesenchymal interactions in hepatocarcinogenesis
10.1038/sj.bjc.6604440 · 2008 · External reference
Telomerase activity and survival of patients with node-positive breast cancer
10.1093/jnci/89.24.1874 · 1997 · External reference
Molecular diagnostics of gliomas: the clinical perspective
10.1007/s00401-010-0750-6 · 2010 · External reference
Molecular dissection of telomeric repeat-containing RNA biogenesis unveils the presence of distinct and multiple regulatory pathways
10.1128/mcb.00460-10 · 2010 · External reference
Epigenetic regulation of telomeres in human cancer
10.1038/onc.2008.289 · 2008 · External reference
DNA methyltransferases control telomere length and telomere recombination in mammalian cells
10.1038/ncb1386 · 2006 · External reference
Pilocytic astrocytomas have telomere-associated promyelocytic leukemia bodies without alternatively lengthened telomeres
10.2353/ajpath.2010.100468 · 2010 · External reference
Alternative lengthening of telomeres in human glioma stem cells
10.1002/stem.600 · 2011 · External reference
The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase
10.1093/nar/gkq296 · 2010 · External reference
New therapeutic approach for brain tumors: intranasal delivery of telomerase inhibitor GRN163
10.1215/15228517-2007-052 · 2008 · External reference
The telomerase antagonist, imetelstat, efficiently targets glioblastoma tumor-initiating cells leading to decreased proliferation and tumor growth
10.1158/1078-0432.ccr-09-2850 · 2010 · External reference
Antitumor effects of specific telomerase inhibitor GRN163 in human glioblastoma xenografts
10.1215/s1152851704000055 · 2004 · External reference
Imetelstat (GRN163L)-telomerase-based cancer therapy
10.1007/978-3-642-01222-8_16 · 2010 · External reference
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
10.1016/j.ccr.2009.12.020 · 2010 · External reference