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References from Superior Therapeutic Index of Calmangafodipir in Comparison to Mangafodipir as a Chemotherapy Adjunct. Local targets link to admitted publications; unresolved targets remain external evidence.
Redox modulation of chemotherapy-induced tumor cell killing and normal tissue toxicity [editorial]
10.1093/jnci/djj065 · 2006 · External reference
Oxygen toxicity: a radical explanation
10.1242/jeb.201.8.1203 · 1998 · External reference
Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts
10.1073/pnas.93.21.11853 · 1996 · External reference
Acetaminophen-induced hepatotoxicity in mice occurs with inhibition of activity and nitration of mitochondrial manganese superoxide dismutase
10.1124/jpet.110.176321 · 2010 · External reference
Superoxide dismutase in redox biology: the roles of super-oxide and hydrogen peroxide
10.2174/187152011795677544 · 2011 · External reference
Acetylation of MnSOD directs enzymatic activity responding to cellular nutrient status or oxidative stress
10.18632/aging.100291 · 2011 · External reference
Targeting the TGF-β1 pathway to prevent normal tissue injury after cancer therapy
10.1634/theoncologist.2009-s101 · 2010 · External reference
What can ecology teach us about cancer?
10.1593/tlo.11154 · 2011 · External reference
Expression of manganese superoxide dismutase reduces tumor control radiation dose: gene-radiotherapy
1995 · External reference
A recombinant MnSOD is radioprotective for normal cells and radiosensitizing for tumor cells
10.1016/j.freeradbiomed.2008.10.030 · 2009 · External reference
Anticancer therapy by overexpression of superoxide dismutase
10.1089/15230860152409095 · 2001 · External reference
Controlling tumor growth by modulating endogenous production of reactive oxygen species
10.1158/0008-5472.948.65.3 · 2005 · External reference
The magnetic resonance imaging contrast agent mangafodipir exerts antitumor activity via a previously described superoxide dismutase mimetic activity [letter to the editor]
10.1158/0008-5472.can-05-2053 · 2006 · External reference
Improvement of the therapeutic index of anticancer drugs by the superoxide dismutase mimic mangafodipir
10.1093/jnci/djj049 · 2006 · External reference
Effects of MnDPDP and ICRF-18[7] on doxorubicin-induced cardiotoxicity and anticancer activity
10.1593/tlo.11304 · 2012 · External reference
Mangafodipir as a cytoprotective adjunct to chemotherapy—a case report
10.1080/02841860802680427 · 2009 · External reference
10.1593/tlo.11277 · 2012 · Admitted local publication
Mangafodipir prevents liver injury induced by acetaminophen in the mouse
10.1016/s0168-8278(03)00325-8 · 2003 · External reference
Antioxidant activity of mangafodipir is not a new finding [letter to the editor]
10.1016/j.jhep.2004.02.022 · 2004 · External reference
Influence of chronic MnCl2 and EDTA treatment on tissue levels and urinary excretion of trace metals in rats
10.1007/bf01056081 · 1982 · External reference
Metabolism and pharmacokinetics of MnDPDP in man
10.1080/02841859709172400 · 1997 · External reference
NMR relaxation studies with MnDPDP
10.1080/02841859709172403 · 1997 · External reference
Applications of manganese-enhanced magnetic resonance imaging (MEMRI) to imaging of the heart
10.1002/nbm.943 · 2004 · External reference
Manganese dipyridoxyl diphosphate: MRI contrast agent with antioxidative and cardioprotective properties?
10.1006/bbrc.1998.0131 · 1999 · External reference
Cardioprotective effects of the MR contrast agent MnDPDP and its metabolite MnPLED upon reperfusion of the ischemic porcine myocardium
10.1080/028418501127347340 · 2001 · External reference
Manganese(II) N,N′-dipyridoxylethylenediamine-N,N′-diacetate 5,5-bis (phosphate)
1989 · External reference
Stability and transmetallation of the magnetic resonance contrast agent MnDPDP measured by EPR
10.1007/s007750100290 · 2002 · External reference
Comparison of manganese biodistribution and MR contrast enhancement in rats after intravenous injection of MnDPDP and MnCl2
10.1080/02841859709172402 · 1997 · External reference
Guidelines for the welfare and use of animals in cancer research
10.1038/sj.bjc.6605642 · 2010 · External reference
Manganese toxicity upon overexposure
10.1002/nbm.931 · 2004 · External reference
Zinc homeostasis in humans
10.1093/jn/130.5.1360s · 2000 · External reference
Zinc content of normal human serum and its correlation with some hematic parameters
10.1007/bf00205198 · 1994 · External reference
Activation of super-oxide dismutases: putting the metal to the pedal
10.1016/j.bbamcr.2006.05.003 · 2006 · External reference
Active versus passive absorption kinetics as the basis for selective protection of normal tissues by S-2-(3-aminopropylamino)-ethylphosphorothioic acid
1980 · External reference
Radioprotectors and mitigators of radiation-induced normal tissue injury
10.1634/theoncologist.2009-s104 · 2010 · External reference
Overexpression of extracellular superoxide dismutase protects mice from radiation-induced lung injury
10.1016/s0360-3016(03)01369-5 · 2003 · External reference
Role of superoxide dismutase in cancer: a review
2003 · External reference
The role of manganese superoxide dismutase in inflammation defense
2011 · External reference
Mutations in the SOD2 promoter reveal a molecular basis for an activating protein 2-dependent dysregulation of manganese superoxide dismutase expression in cancer cells
10.1158/1541-7786.mcr-08-0253 · 2008 · External reference
Comparison of effects of two polymorphic variants of manganese superoxide dismutase on human breast MCF-[7] cancer cell phenotype
1999 · External reference
Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts
10.1126/science.275.5306.1649 · 1997 · External reference
Prooxidant states and tumor promotion
10.1126/science.2981433 · 1985 · External reference
Production of large amounts of hydrogen peroxide by human tumor cells
1991 · External reference
Enhanced ROS production in oncogenically transformed cells potentiates c-Jun N-terminal kinase and p3[8] mitogen-activated protein kinase activation and sensitization to genotoxic stress
10.1128/mcb.21.20.6913-6926.2001 · 2001 · External reference
The role of manganese superoxide dismutase in the growth of pancreatic adenocarcinoma
2003 · External reference
Manganese superoxide dismutase induces p53-dependent senescence in colorectal cancer cells
10.1128/mcb.25.17.7758-7769.2005 · 2005 · External reference
Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells
10.1073/pnas.90.7.3113 · 1993 · External reference
Suppression of the malignant phenotype of human glioma cells by overexpression of manganese superoxide dismutase
10.1038/sj.onc.1200852 · 1997 · External reference
Transfection and expression of MnSOD cDNA decreases tumor malignancy of human oral squamous carcinoma SCC-2[5] cells
10.1089/hum.1997.8.5-585 · 1997 · External reference
Overexpression of manganese superoxide dismutase in DU14[5] human prostate carcinoma cells has multiple effects on cell phenotype
10.1002/(sici)1097-0045(19980515)35:3<221::aid-pros8>3.0.co;2-j · 1998 · External reference
Immune parameters affecting the efficacy of chemotherapeutic regimens
10.1038/nrclinonc.2010.223 · 2011 · External reference
Neutrophil/lymphocyte ratio predicts chemotherapy outcomes in patients with advanced colorectal cancer
10.1038/bjc.2011.100 · 2011 · External reference
Inhibition of tumour promotion by a biomimetic SOD
10.1126/science.6857269 · 1983 · External reference
Mangafodipir (MnDPDP) and MnCl2-induced endothelium-dependent relaxation in bovine mesenteric arteries
10.1016/s0022-3565(25)23807-1 · 1994 · External reference
Manganese superoxide dismutase, MnSOD and its mimics
10.1016/j.bbadis.2011.12.002 · 2012 · External reference