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References from Arsenic Trioxide as a Vascular Disrupting Agent: Synergistic Effect with Irinotecan on Tumor Growth Delay in a CT26 Allograft Model. Local targets link to admitted publications; unresolved targets remain external evidence.
Arsenical-based cancer drugs
10.1016/j.ctrv.2007.05.001 · 2007 · External reference
Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide
10.1056/nejm199811053391901 · 1998 · External reference
United States multicenter study of arsenic trioxide in relapsed acute promyelocytic leukemia
10.1200/jco.2001.19.18.3852 · 2001 · External reference
Arsenic trioxide—an old drug rediscovered
10.1016/j.blre.2010.04.001 · 2010 · External reference
Mechanisms of action of arsenic trioxide
2002 · External reference
Arsenic trioxide causes selective necrosis in solid murine tumors by vascular shutdown
1999 · External reference
Tumor cells resistant to a microtubuledepolymerizing hemiasterlin analogue, HTI-286, have mutations in α- or β-tubulin and increased microtubule stability
10.1021/bi049300+ · 2004 · External reference
Use of arsenic trioxide as an antivascular and thermosensitizing agent in solid tumors
10.1038/sj.neo.7900123 · 2000 · External reference
Arsenic trioxide induces dose- and time-dependent apoptosis of endothelium and may exert an antileukemic effect via inhibition of angiogenesis
10.1182/blood.v96.4.1525 · 2000 · External reference
Synergistic interaction with arsenic trioxide and fractionated radiation in locally advanced murine tumor
2002 · External reference
Arsenic trioxide enhances radiation response of 9L glioma in the rat brain
10.1667/rr3069 · 2003 · External reference
Preferential action of arsenic trioxide in solid-tumor microenvironment enhances radiation therapy
10.1016/j.ijrobp.2004.12.058 · 2005 · External reference
Arsenic targets tubulins to induce apoptosis in myeloid leukemia cells
1999 · External reference
Disrupting tumour blood vessels
10.1038/nrc1628 · 2005 · External reference
Disrupting established tumor blood vessels: an emerging therapeutic strategy for cancer
10.1002/cncr.24975 · 2010 · External reference
Assessment of the early effects of 5,6-dimethylxanthenone-4-acetic acid using macromolecular contrast media-enhanced magnetic resonance imaging: ectopic versus orthotopic tumors
10.1016/j.ijrobp.2008.07.043 · 2008 · External reference
DCE-MRI biomarkers in the clinical evaluation of antiangiogenic and vascular disrupting agents
10.1038/sj.bjc.6603515 · 2007 · External reference
Perfusion MRI in the early clinical development of antivascular drugs: decorations or decision making tools?
10.1007/s00259-010-1451-z · 2010 · External reference