Research graph
References from Changes in the Secretory Profile of NSCLC-Associated Fibroblasts after Ablative Radiotherapy: Potential Impact on Angiogenesis and Tumor Growth. Local targets link to admitted publications; unresolved targets remain external evidence.
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
10.1002/ijc.25516 · 2010 · External reference
Treatment advances for medically inoperable non-small-cell lung cancer: emphasis on prospective trials
10.1016/s1470-2045(09)70103-2 · 2009 · External reference
Advances in treatment techniques: stereotactic body radiation therapy and the spread of hypofractionation
10.1097/ppo.0b013e31821f7dbd · 2011 · External reference
Stereotactic ablative radiation therapy for primary lung tumors
10.1097/ppo.0b013e31820a7f80 · 2011 · External reference
Stereotactic radiotherapy reduces treatment cost while improving overall survival and local control over standard fractionated radiation therapy for medically inoperable non-small-cell lung cancer
10.1097/coc.0b013e3181ec63ae · 2011 · External reference
Stereotactic radiation therapy: changing treatment paradigms for stage I nonsmall cell lung cancer
10.1097/cco.0b013e328341ee11 · 2011 · External reference
Stereotactic ablative radiotherapy for stage I NSCLC: recent advances and controversies
2011 · External reference
The hallmarks of cancer
10.1016/s0092-8674(00)81683-9 · 2000 · External reference
Putting tumours in context
10.1038/35094059 · 2001 · External reference
Accessories to the crime: functions of cells recruited to the tumor microenvironment
10.1016/j.ccr.2012.02.022 · 2012 · External reference
Hallmarks of cancer: the next generation
10.1016/j.cell.2011.02.013 · 2011 · External reference
High-dose single-fraction radiotherapy: exploiting a new biology?
10.1016/j.ijrobp.2008.02.003 · 2008 · External reference
Radiation and the microenvironment—tumorigenesis and therapy
10.1038/nrc1735 · 2005 · External reference
The convergence of radiation and immunogenic cell death signaling pathways
10.3389/fonc.2012.00088 · 2012 · External reference
Regulatory T cells in radiotherapeutic responses
10.3389/fonc.2012.00090 · 2012 · External reference
Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor
10.4049/jimmunol.174.12.7516 · 2005 · External reference
Radiotherapy promotes tumor-specific effector CD8+ T cells via dendritic cell activation
10.4049/jimmunol.1200563 · 2012 · External reference
Therapeutic effects of ablative radiation on local tumor require CD8+ T cells: changing strategies for cancer treatment
10.1182/blood-2009-02-206870 · 2009 · External reference
Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice
10.1126/science.1060191 · 2001 · External reference
Tumor response to radiotherapy regulated by endothelial cell apoptosis
10.1126/science.1082504 · 2003 · External reference
Stromal fibroblasts in cancer initiation and progression
10.1038/nature03096 · 2004 · External reference
Stromal fibroblasts in cancer: a novel tumor-promoting cell type
10.4161/cc.5.15.3112 · 2006 · External reference
Fibroblasts in cancer
10.1038/nrc1877 · 2006 · External reference
The role of tumor stroma in cancer progression and prognosis: emphasis on carcinoma-associated fibroblasts and non-small cell lung cancer
10.1097/jto.0b013e3181f8a1bd · 2011 · External reference
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
10.1016/j.cell.2005.02.034 · 2005 · External reference
Importance of CCl2-CCR2A/2B signaling for monocyte migration into spheroids of breast cancer-derived fibroblasts
10.1016/j.imbio.2010.05.019 · 2010 · External reference
Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells
10.1038/ncb1658 · 2007 · External reference
Malignant cells facilitate lung metastasis by bringing their own soil
10.1073/pnas.1016234107 · 2010 · External reference
Irradiated mammary gland stroma promotes the expression of tumorigenic potential by unirradiated epithelial cells
2000 · External reference
Senescent human fibroblasts increase the early growth of xenograft tumors via matrix metalloproteinase secretion
10.1158/0008-5472.can-06-3452 · 2007 · External reference
Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion
10.1038/ncb1909 · 2009 · External reference
Crosstalk to stromal fibroblasts induces resistance of lung cancer to epidermal growth factor receptor tyrosine kinase inhibitors
10.1158/1078-0432.ccr-09-1001 · 2009 · External reference
Fibroblast-secreted hepatocyte growth factor mediates epidermal growth factor receptor tyrosine kinase inhibitor resistance in triple-negative breast cancers through paracrine activation of Met
10.1186/bcr3224 · 2012 · External reference
Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
10.1038/nature11183 · 2012 · External reference
Fibroblast stimulation of blood vessel development and cancer cell invasion in a subrenal capsule xenograft model: stress-induced premature senescence does not increase effect
10.1593/neo.07205 · 2007 · External reference
Cancer-associated fibroblasts from human NSCLC survive ablative doses of radiation but their invasive capacity is reduced
10.1186/1748-717x-7-59 · 2012 · External reference
Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts
10.1074/jbc.274.51.36505 · 1999 · External reference
Simultaneous detection of 15 human cytokines in a single sample of stimulated peripheral blood mononuclear cells
2003 · External reference
Multiplex bead array assays for detection of soluble cytokines: comparisons of sensitivity and quantitative values among kits from multiple manufacturers
10.1002/cyto.b.20021 · 2004 · External reference
Linking genome and proteome by mass spectrometry: large-scale identification of yeast proteins from two dimensional gels
10.1073/pnas.93.25.14440 · 1996 · External reference
Exponentially modified protein abundance index (emPAI) for estimation of absolute protein amount in proteomics by the number of sequenced peptides per protein
10.1074/mcp.m500061-mcp200 · 2005 · External reference
Microelectronic cell sensor assay for detection of cytotoxicity and prediction of acute toxicity
10.1016/j.tiv.2005.12.008 · 2006 · External reference
Dynamic and label-free cell-based assays using the real-time cell electronic sensing system
10.1089/adt.2006.4.597 · 2006 · External reference
Kinetic cell-based morphological screening: prediction of mechanism of compound action and off-target effects
10.1016/j.chembiol.2009.05.011 · 2009 · External reference
Mechanistic modeling of the effects of myoferlin on tumor cell invasion
10.1073/pnas.1116327108 · 2011 · External reference
In vitro angiogenesis: endothelial cell tube formation on gelled basement membrane extract
10.1038/nprot.2010.6 · 2010 · External reference
Replicative senescence of human skin fibroblasts correlates with a loss of regulation and overexpression of collagenase activity
10.1016/0014-4827(89)90372-8 · 1989 · External reference
Stress-induced premature senescence (SIPS)—influence of SIPS on radiotherapy
10.1269/jrr.07081 · 2008 · External reference
Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species
10.1074/jbc.274.12.7936 · 1999 · External reference
Chemokines at the crossroads of tumor-fibroblast interactions that promote malignancy
10.1189/jlb.0310182 · 2011 · External reference
Cancer-associated fibroblasts are activated in incipient neoplasia to orchestrate tumor-promoting inflammation in an NF-κB-dependent manner
10.1016/j.ccr.2009.12.041 · 2010 · External reference
Radiation-induced matrix production of lung fibroblasts is regulated by interleukin-8
10.1080/09553000802641136 · 2009 · External reference
Radiation to stromal fibroblasts increases invasiveness of pancreatic cancer cells through tumor-stromal interactions
10.1158/0008-5472.can-03-2464 · 2004 · External reference
Microenvironment-mediated resistance to anticancer therapies
2012 · External reference
Basic fibroblast growth factor protects endothelial cells against radiation-induced programmed cell death in vitro and in vivo
1994 · External reference
Fibroblast growth factor 2—a predictor of outcome for patients irradiated for stage II–III nonsmall-cell lung cancer
10.1016/j.ijrobp.2010.08.048 · 2012 · External reference
Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors
10.1038/nature11249 · 2012 · External reference
Dual inhibition of Met kinase and angiogenesis to overcome HGF-induced EGFR-TKI resistance in EGFR mutant lung cancer
10.1016/j.ajpath.2012.05.023 · 2012 · External reference
Mechanisms of macrophage migration inhibitory factor (MIF)-dependent tumor microenvironmental adaptation
10.1016/j.yexmp.2009.01.001 · 2009 · External reference
CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth
10.4161/cc.20717 · 2012 · External reference
Angiogenesis gene expression profiling in xenograft models to study cellular interactions
10.1016/j.yexcr.2004.06.014 · 2004 · External reference
Targeting SDF-1/CXCR4 to inhibit tumour vasculature for treatment of glioblastomas
10.1038/bjc.2011.169 · 2011 · External reference
