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References from Diverse Responses to Vascular Disrupting Agent Combretastatin A4 Phosphate: A Comparative Study in Rats with Hepatic and Subcutaneous Tumor Allografts Using MRI Biomarkers, Microangiography, and Histopathology. Local targets link to admitted publications; unresolved targets remain external evidence.
A review on various targeted anticancer therapies
10.1007/s11523-012-0212-2 · 2012 · External reference
Vascular targeting as a strategy for cancer therapy
10.1056/nejm199808133390711 · 1998 · External reference
Cancer treatment by targeted drug delivery to tumor vasculature in a mouse model
10.1126/science.279.5349.377 · 1998 · External reference
Relationship between tumour endothelial cell apoptosis and tumour blood flow shutdown following treatment with the antivascular agent DMXAA in mice
10.1038/sj.bjc.6601606 · 2004 · External reference
Visualizing the acute effects of vascular-targeted therapy in vivo using intravital microscopy and magnetic resonance imaging: correlation with endothelial apoptosis, cytokine induction, and treatment outcome
10.1593/neo.06748 · 2007 · External reference
Rat tumor response to the vascular-disrupting agent 5,6-dimethylxanthenone-4-acetic acid as measured by dynamic contrast-enhanced magnetic resonance imaging, plasma 5-hydroxyindoleacetic acid levels, and tumor necrosis
10.1593/neo.05739 · 2006 · External reference
Induction of intratumoral tumor necrosis factor (TNF) synthesis and hemorrhagic necrosis by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF knockout mice
1999 · External reference
Phase I clinical trial of weekly combretastatin A4 phosphate: clinical and pharmacokinetic results
10.1200/jco.2003.05.185 · 2003 · External reference
Disrupting tumour blood vessels
10.1038/nrc1628 · 2005 · External reference
The clinical development of tubulin binding vascular disrupting agents
2010 · External reference
Unresolved reference
External reference
Novel vascular targeting/disrupting agents: combretastatin A4 phosphate and related compounds
10.1007/s11912-005-0033-x · 2005 · External reference
Treatment of rodent liver tumor with combretastatin a4 phosphate: noninvasive therapeutic evaluation using multiparametric magnetic resonance imaging in correlation with micro-angiography and histology
10.1097/rli.0b013e31818e5ace · 2009 · External reference
Assessment of pharmacodynamic vascular response in a phase I trial of combretastatin A4 phosphate
10.1200/jco.2003.05.186 · 2003 · External reference
Phase II trial of combretastatin A4 phosphate, carboplatin, and paclitaxel in patients with platinum-resistant ovarian cancer
10.1093/annonc/mdq708 · 2011 · External reference
Combretastatin A4 phosphate
10.1097/00001813-200403000-00001 · 2004 · External reference
Mechanisms associated with tumor vascular shut-down induced by combretastatin A-4 phosphate: intravital microscopy and measurement of vascular permeability
2001 · External reference
Nitric oxide synthase inhibition enhances the tumor vascular-damaging effects of combretastatin a-4 3-o-phosphate at clinically relevant doses
10.1158/1078-0432.ccr-08-2906 · 2009 · External reference
Characterizing the tumor response to treatment with combretastatin A4 phosphate
10.1016/j.ijrobp.2006.12.051 · 2007 · External reference
A dual-targeting anticancer approach: soil and seed principle
10.1148/radiol.11102120 · 2011 · External reference
A phase Ib trial of CA4P (combretastatin A-4 phosphate), carboplatin, and paclitaxel in patients with advanced cancer
10.1038/sj.bjc.6605650 · 2010 · External reference
Combination of combretastatin A4 phosphate and doxorubicin-containing liposomes affects growth of B16-F10 tumors
10.18388/abp.2009_2528 · 2009 · External reference
Phase I trial of combretastatin a-4 phosphate with carboplatin
10.1158/1078-0432.ccr-04-1434 · 2005 · External reference
Enhanced antitumor efficacy of a vascular disrupting agent combined with an antiangiogenic in a rat liver tumor model evaluated by multiparametric MRI
10.1371/journal.pone.0041140 · 2012 · External reference
Tumour vascular disrupting agents: combating treatment resistance
10.1259/bjr/36205483 · 2008 · External reference
The vascular response of tumor and normal tissues in the rat to the vascular targeting agent, combretastatin A-4-phosphate, at clinically relevant doses
2002 · External reference
Vascular disrupting agents: a novel mechanism of action in the battle against non-small cell lung cancer
10.1634/theoncologist.2008-0287 · 2009 · External reference
Vascular targeted therapies in oncology
10.1007/s00441-008-0646-0 · 2009 · External reference
Comparison of two vascular-disrupting agents at a clinically relevant dose in rodent liver tumors with multiparametric magnetic resonance imaging biomarkers
10.1097/cad.0b013e328349dd60 · 2012 · External reference
Multiparametric MRI biomarkers for measuring vascular disrupting effect on cancer
10.4329/wjr.v3.i1.1 · 2011 · External reference
Cancer models—multiparametric applications of clinical MRI in rodent hepatic tumor model
10.1007/978-1-61779-219-9_26 · 2011 · External reference
Magnetic resonance imaging measurements of the response of murine and human tumors to the vascular-targeting agent ZD6126
10.1158/1078-0432.ccr-03-0417 · 2004 · External reference
Diffusion-weighted and macromolecular contrast enhanced MRI of tumor response to antivascular therapy with ZD6126
10.4161/cbt.6.9.4634 · 2007 · External reference
Effect of vascular targeting agent in rat tumor model: dynamic contrast-enhanced versus diffusion-weighted MR imaging
10.1148/radiol.2372041638 · 2005 · External reference
Liver tumor model with implanted rhabdomyosarcoma in rats: MR imaging, microangiography, and histopathologic analysis
10.1148/radiol.2392050277 · 2006 · External reference
A biomathematical approach to clinical tumor growth
10.1002/1097-0142(196111/12)14:6<1272::aid-cncr2820140618>3.0.co;2-h · 1961 · External reference
Diffusion-weightedMRI of hepatic tumor in rats: comparison between in vivo and postmortem imaging acquisitions
10.1002/jmri.21675 · 2009 · External reference
Morphological, functional and metabolic imaging biomarkers: assessment of vascular-disrupting effect on rodent liver tumours
10.1007/s00330-010-1743-5 · 2010 · External reference
New guidelines to evaluate the response to treatment in solid tumors
10.1093/jnci/92.3.205 · 2000 · External reference
Evaluation of the response to treatment of solid tumours—a consensus statement of the International Cancer Imaging Society
10.1038/sj.bjc.6601843 · 2004 · External reference
Measurement of tumour response to cancer treatment: morphologic imaging role
2007 · External reference
Multiparametric imaging of tumor response to therapy
10.1148/radiol.10091760 · 2010 · External reference
Measuring tumour vascular response to antivascular and antiangiogenic drugs
10.1259/bjr/30165281 · 2003 · External reference
Effects of intracellular organelles on the apparent diffusion coefficient of water molecules in cultured human embryonic kidney cells
10.1002/mrm.22666 · 2011 · External reference
Rat model of reperfused partial liver infarction: characterization with multiparametric magnetic resonance imaging, microangiography, and histomorphology
10.1080/02841850802647021 · 2009 · External reference
Magnetic resonance imaging, microangiography, and histology in a rat model of primary liver cancer
10.1097/00004424-199209000-00006 · 1992 · External reference
Diffusion-weighted MR imaging in monitoring the effect of a vascular targeting agent on rhabdomyosarcoma ingrats
10.1148/radiol.2343031721 · 2005 · External reference
Modulation of chemotherapeutic efficacy by vascular disrupting agents: optimizing the sequence and schedule
10.1200/jco.2011.39.3934 · 2012 · External reference
Effect of host microenvironment on the microcirculation of human colon adenocarcinoma
1997 · External reference
Metastasis-associated gene expression profile of liver and subcutaneous lesions derived from mouse pheochromocytoma cells
10.1002/mc.20388 · 2008 · External reference