Research graph
References from Down-regulation of miR-21 Induces Differentiation of Chemoresistant Colon Cancer Cells and Enhances Susceptibility to Therapeutic Regimens. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
2011 · External reference
Tumour stem cells and drug resistance
10.1038/nrc1590 · 2005 · External reference
Colon cancer stem cells: implications in carcinogenesis
10.2741/3811 · 2011 · External reference
Phenotypic characterization of human colorectal cancer stem cells
10.1073/pnas.0703478104 · 2007 · External reference
Age-related increase in colorectal cancer stem cells in macroscopically normal mucosa of patients with adenomas: a risk factor for colon cancer
10.1016/j.bbrc.2008.10.179 · 2009 · External reference
Cancer stem cells
10.1056/nejmra061808 · 2006 · External reference
Difluorinated-curcumin (CDF): a novel curcumin analog is a potent inhibitor of colon cancer stem-like cells
10.1007/s11095-010-0336-y · 2011 · External reference
Elimination of colon cancer stem-like cells by the combination of curcumin and FOLFOX
10.1593/tlo.09193 · 2009 · External reference
MicroRNA-21 induces stemness by downregulating transforming growth factor beta receptor 2 (TGFβR2) in colon cancer cells
10.1093/carcin/bgr246 · 2012 · External reference
A microRNA in a multiple-turnover RNAi enzyme complex
10.1126/science.1073827 · 2002 · External reference
MicroRNA: implications for cancer
10.1007/s00428-007-0532-2 · 2008 · External reference
Advantages of genomic complexity: bioinformatics opportunities in microRNA cancer signatures
10.1136/amiajnl-2011-000419 · 2012 · External reference
MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene
10.1038/onc.2008.72 · 2008 · External reference
MicroRNA-21: from cancer to cardiovascular disease
10.2174/138945010791591403 · 2010 · External reference
The diverse functions of microRNAs in animal development and disease
10.1016/j.devcel.2006.09.009 · 2006 · External reference
Combination of dasatinib and curcumin eliminates chemo-resistant colon cancer cells
10.1186/1750-2187-6-7 · 2011 · External reference
Curcumin enhances the effects of 5-fluorouracil and oxaliplatin in mediating growth inhibition of colon cancer cells by modulating EGFR and IGF-1R
10.1002/ijc.23097 · 2008 · External reference
Curcumin targets FOLFOX-surviving colon cancer cells via inhibition of EGFRs and IGF-1R
2010 · External reference
Epidermal growth factor receptor (EGFR)-related protein inhibits multiple members of the EGFR family in colon and breast cancer cells
10.1158/1535-7163.mct-04-0280 · 2005 · External reference
The Wnt/β-catenin pathway regulates growth and maintenance of colonospheres
10.1186/1476-4598-9-212 · 2010 · External reference
OncomiR addiction in an in vivo model of microRNA-21-induced pre-B-cell lymphoma
10.1038/nature09284 · 2010 · External reference
MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
10.1038/sj.onc.1210856 · 2008 · External reference
Gastrointestinal differentiation marker Cytokeratin 20 is regulated by homeobox gene CDX1
10.1073/pnas.0812904106 · 2009 · External reference
Activation of β-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
10.1126/science.275.5307.1787 · 1997 · External reference
Wnt/beta-catenin/tcf signaling: a critical pathway in gastrointestinal tumorigenesis
10.1159/000066755 · 2002 · External reference
Mutational analysis of the APC/β-catenin/Tcf pathway in colorectal cancer
1998 · External reference
Induction of glutathione peroxidase 4 expression during enterocytic cell differentiation
10.1074/jbc.m110.216028 · 2011 · External reference
Schlafen-3 decreases cancer stem cell marker expression and autocrine/juxtacrine signaling in FOLFOX-resistant colon cancer cells
10.1152/ajpgi.00403.2010 · 2011 · External reference
Gemcitabine sensitivity can be induced in pancreatic cancer cells through modulation of miR-200 and miR-21 expression by curcumin or its analogue CDF
10.1158/0008-5472.can-09-4598 · 2010 · External reference