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References from Fusicoccin A, a Phytotoxic Carbotricyclic Diterpene Glucoside of Fungal Origin, Reduces Proliferation and Invasion of Glioblastoma Cells by Targeting Multiple Tyrosine Kinases. Local targets link to admitted publications; unresolved targets remain external evidence.
The 2007 WHO classification of tumours of the central nervous system
10.1007/s00401-007-0243-4 · 2007 · External reference
Malignant astrocytic glioma: genetics, biology, and paths to treatment
10.1101/gad.1596707 · 2007 · External reference
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
10.1016/s1470-2045(09)70025-7 · 2009 · External reference
Molecular pathology of malignant gliomas
10.1146/annurev.pathol.1.110304.100043 · 2006 · External reference
An integrated genomic analysis of human glioblastoma multiforme
10.1126/science.1164382 · 2008 · External reference
Safety and efficacy of erlotinib in first-relapse glioblastoma: a phase II open-label study
10.1093/neuonc/noq072 · 2010 · External reference
Efficacy and safety of bevacizumab in glioblastomas
10.2174/092986712799320646 · 2012 · External reference
Cilengitide in patients with recurrent glioblastoma: the results of NABTC 03-02, a phase II trial with measures of treatment delivery
10.1007/s11060-011-0650-1 · 2012 · External reference
Fungal metabolites: structural diversity as incentive for anticancer drug development
10.1007/s11101-010-9198-5 · 2010 · External reference
Natural products as sources of new drugs over the 30 years from 1981 to 2010
10.1021/np200906s · 2012 · External reference
Radiation and concomitant weekly administration of paclitaxel in patients with glioblastoma multiforme. A phase II study
10.1023/a:1006386114104 · 1999 · External reference
Experience with irinotecan for the treatment of malignant glioma
10.1215/15228517-2008-075 · 2009 · External reference
In vitro drug response and molecular markers associated with drug resistance in malignant gliomas
10.1158/1078-0432.ccr-05-1830 · 2006 · External reference
Fusicoccin: a new wilting toxin produced by Fusicoccum amygdali
1964 · External reference
Dynamic interactions between 14-3-3 proteins and phosphoproteins regulate diverse cellular processes
10.1042/bj20031332 · 2004 · External reference
Fusicoccin signaling reveals 14-3-3 protein function as a novel step in left-right patterning during amphibian embryogenesis
10.1242/dev.00698 · 2003 · External reference
Phosphopeptide-dependent labeling of 14-3-3ζ proteins by fusicoccinbased fluorescent probes
10.1002/anie.201106995 · 2012 · External reference
Isoform-specific expression of 14-3-3 proteins in human astrocytoma
10.1016/j.jns.2008.08.040 · 2009 · External reference
Fusicoccin-A selectively induces apoptosis in tumor cells after interferon-α priming
10.1016/j.canlet.2010.01.009 · 2010 · External reference
Produzione di fusicoccina in scala pilota
1968 · External reference
Stimulation of Orobanche ramosa seed germination by fusicoccin derivatives: a structure-activity relationship study
10.1016/j.phytochem.2005.10.010 · 2006 · External reference
Reversal of temporal and spatial heterogeneities in tumor perfusion identifies the tumor vascular tone as a tunable variable to improve drug delivery
10.1158/1535-7163.mct-05-0472 · 2006 · External reference
FAK is a critical regulator of neuroblastoma liver metastasis
10.18632/oncotarget.732 · 2012 · External reference
Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
10.1016/0022-1759(83)90303-4 · 1983 · External reference
Video-microscopic extraction of specific information on cell proliferation and migration in vitro
10.1016/j.yexcr.2008.06.010 · 2008 · External reference
Screening of anti-glioma effects induced by sigma-1 receptor ligands: potential new use for old anti-psychiatric medicines
10.1016/j.ejca.2009.07.011 · 2009 · External reference
Tracking of migrating cells under phase-contrast video microscopy with combined mean-shift processes
10.1109/tmi.2005.846851 · 2005 · External reference
In vitro anticancer activity, toxicity and structure-activity relationships of phyllostictine A, a natural oxazatricycloalkenone produced by the fungus Phyllosticta cirsii
10.1016/j.taap.2011.03.027 · 2011 · External reference
N-(2-{3-[3,5-bis(trifluoromethyl) phenyl]ureido}ethyl)-glycyrrhetinamide (6b): a novel anticancer glycyrrhetinic acid derivative that targets the proteasome and displays anti-kinase activity
10.1021/jm200285z · 2011 · External reference
4-IBP, a sigma1 receptor agonist, decreases the migration of human cancer cells, including glioblastoma cells, in vitro and sensitizes them in vitro and in vivo to cytotoxic insults of proapoptotic and proautophagic drugs
10.1593/neo.07130 · 2007 · External reference
Galectin 1 proangiogenic and promigratory effects in the Hs683 oligodendroglioma model are partly mediated through the control of BEX2 expression
10.1593/neo.81526 · 2009 · External reference
Trivanillic polyphenols with anticancer cytostatic effects through the targeting of multiple kinases and intracellular Ca2+ release
10.1111/j.1582-4934.2011.01403.x · 2012 · External reference
Characterization of p53 and p21 functional interactions in glioma cells en route to apoptosis
10.1093/jnci/89.14.1036 · 1997 · External reference
Downregulation of PRDX1 by promoter hypermethylation is frequent in 1p/19q-deleted oligodendroglial tumours and increases radio- and chemosensitivity of Hs683 glioma cells in vitro
10.1038/onc.2011.513 · 2012 · External reference
Focal adhesion and actin dynamics: a place where kinases and proteases meet to promote invasion
10.1016/j.tcb.2004.03.011 · 2004 · External reference
Tyrosine kinases as targets in cancer therapy—successes and failures
10.1517/14728222.7.2.215 · 2003 · External reference
The role of focal-adhesion kinase in cancer—a new therapeutic opportunity
10.1038/nrc1647 · 2005 · External reference
Focal adhesion kinase and its signaling pathways in cell migration and angiogenesis
10.1016/j.addr.2010.11.001 · 2003 · External reference
Focal adhesion kinase: the first ten years
10.1242/jcs.00373 · 2003 · External reference
Src kinases as therapeutic targets for cancer
10.1038/nrclinonc.2009.129 · 2009 · External reference
Attenuation of the expression of the focal adhesion kinase induces apoptosis in tumor cells
1996 · External reference
FAK regulates biological processes important for the pathogenesis of cancer
10.1023/a:1023725029589 · 2003 · External reference
αvβ3/αvβ5 Integrins-FAK-RhoB: a novel pathway for hypoxia regulation in glioblastoma
10.1158/0008-5472.can-08-2158 · 2009 · External reference
FAK signaling in anaplastic astrocytoma and glioblastoma tumors
10.1097/00130404-200303000-00008 · 2003 · External reference
Recent advances in the treatment of malignant astrocytoma
10.1200/jco.2005.04.5302 · 2006 · External reference
Role of Eph/ephrin tyrosine kinase in malignant glioma
10.1093/neuonc/nor102 · 2011 · External reference
RhoA/ROCK signaling is critical to FAK activation by cyclic stretch in cardiac myocytes
10.1152/ajpheart.00692.2004 · 2005 · External reference
Phosphorylation of tyrosine 1214 on VEGFR2 is required for VEGF-induced activation of Cdc42 upstream of SAPK2/p38
10.1038/sj.onc.1207034 · 2004 · External reference
Csk, a critical link of g protein signals to actin cytoskeletal reorganization
10.1016/s1534-5807(02)00175-2 · 2002 · External reference
SRC regulates actin dynamics and invasion of malignant glial cells in three dimensions
10.1158/1541-7786.595.2.11 · 2004 · External reference
Expression of the neurotrophin receptors Trk A and Trk B in adult human astrocytoma and glioblastoma
10.1007/bf02706217 · 2003 · External reference
Genetic variations in VEGF and VEGFR2 and glioblastoma outcome
10.1007/s11060-010-0504-2 · 2011 · External reference
The tyrosine kinase pyk2 promotes migration and invasion of glioma cells
10.1593/neo.04712 · 2005 · External reference
The signaling and biological implications of FAK overexpression in cancer
10.1158/1078-0432.ccr-06-0456 · 2006 · External reference
'Pseudopalisading' necrosis in glioblastoma: a familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis
10.1097/00005072-200606000-00001 · 2006 · External reference
Intratumoral hypoxic gradient drives stem cells distribution and MGMT expression in glioblastoma
10.1002/stem.415 · 2010 · External reference
Glioblastoma, cancer stem cells and hypoxia
10.1111/j.1750-3639.2010.00460.x · 2011 · External reference
Frontiers in targeting glioma stem cells
10.1016/j.ejca.2010.11.017 · 2011 · External reference