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References from FAK Inhibition Decreases Hepatoblastoma Survival Both In Vitro and In Vivo. Local targets link to admitted publications; unresolved targets remain external evidence.
Hepatoblastoma
1994 · External reference
Hepatoblastoma—evolution of management and outcome and significance of histology of the resected tumor. A 31-year experience with 40 cases
10.1016/j.jpedsurg.2004.05.020 · 2004 · External reference
Direct interaction of v-Src with the focal adhesion kinase mediated by the Src SH2 domain
10.1091/mbc.5.4.413 · 1994 · External reference
Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase
10.1073/pnas.91.21.10148 · 1994 · External reference
Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: correlation with preinvasive and invasive phenotypes
2000 · External reference
Focal adhesion kinase expression in human neuroblastoma: immunohistochemical and real-time PCR analyses
10.1158/1078-0432.ccr-07-1511 · 2008 · External reference
Functional analysis of focal adhesion kinase (FAK) reduction by small inhibitory RNAs
2004 · External reference
The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells. Involvement of death receptor-related signaling pathways
10.1074/jbc.m910027199 · 2000 · External reference
Inhibition of focal adhesion kinase and src increases detachment and apoptosis in human neuroblastoma cell lines
10.1002/mc.20592 · 2010 · External reference
A small molecule inhibitor, 1,2,4,5-benzenetetraamine tetrahydrochloride, targeting the Y397 site of focal adhesion kinase decreases tumor growth
10.1021/jm800483v · 2008 · External reference
A novel small molecule inhibitor of FAK decreases growth of human pancreatic cancer
10.4161/cc.8.15.9145 · 2009 · External reference
Inhibition of focal adhesion kinase decreases tumor growth in human neuroblastoma
10.4161/cc.9.5.10936 · 2010 · External reference
FAK is involved in invasion and metastasis of hepatocellular carcinoma
10.1007/s10585-010-9306-3 · 2010 · External reference
Mouse-specific residues of claudin-1 limit hepatitis C virus genotype 2a infection in a human hepatocyte cell line
10.1128/jvi.01504-09 · 2010 · External reference
N-MYC regulates focal adhesion kinase expression in human neuroblastoma
10.1074/jbc.m701450200 · 2007 · External reference
Focal adhesion kinase and p53 signaling in cancer cells
10.1016/s0074-7696(07)63003-4 · 2007 · External reference
Cellular characterization of a novel focal adhesion kinase inhibitor
10.1074/jbc.m606695200 · 2007 · External reference
Focal adhesion kinase is overexpressed in hepatocellular carcinoma and can be served as an independent prognostic factor
10.1016/j.jhep.2004.03.029 · 2004 · External reference
Expression and prognostic significance of focal adhesion kinase in hepatocellular carcinoma
10.1007/s00432-010-0806-y · 2010 · External reference
TLR4 agonists inhibit migration and invasion of hepatoblastoma cells
10.1002/pbc.24211 · 2012 · External reference
A critical role for TLR4 in the pathogenesis of necrotizing enterocolitis by modulating intestinal injury and repair
10.4049/jimmunol.179.7.4808 · 2007 · External reference
Activation of phosphatidylinositol-3′-kinase/AKT signaling is essential in hepatoblastoma survival
10.1158/1078-0432.ccr-08-2878 · 2008 · External reference
Rapamycin blocks hepatoblastoma growth in vitro and in vivo implicating new treatment options in high-risk patients
10.1016/j.ejca.2011.12.032 · 2012 · External reference
Subcutaneous and intrahepatic growth of human hepatoblastoma in immunodeficient mice
10.1016/j.jhep.2006.03.018 · 2006 · External reference
Focal adhesion kinase functions as an akt downstream target in migration of colorectal cancer cells
10.1593/tlo.09160 · 2009 · External reference
Intrinsic chemoresistance to gemcitabine is associated with constitutive and laminin-induced phosphorylation of FAK in pancreatic cancer cell lines
10.1186/1476-4598-8-125 · 2009 · External reference
Absence of adhesion triggers differential FAK and SAPKp38 signals in SW620 human colon cancer cells that may inhibit adhesiveness and lead to cell death
10.1159/000071864 · 2003 · External reference
Antitumor activity and pharmacology of a selective focal adhesion kinase inhibitor, PF-562,271
10.1158/0008-5472.can-07-5155 · 2008 · External reference
DNA copy number aberrations in small-cell lung cancer reveal activation of the focal adhesion pathway
10.1038/onc.2010.362 · 2010 · External reference
In vitro evaluation of the Aurora kinase inhibitor VX-680 for hepatoblastoma
10.1007/s00383-012-3086-6 · 2012 · External reference
