Research graph
References from In Vivo c-Met Pathway Inhibition Depletes Human Glioma Xenografts of Tumor-Propagating Stem-Like Cells. Local targets link to admitted publications; unresolved targets remain external evidence.
Brain tumour stem cells
10.1038/nrc1889 · 2006 · External reference
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
10.1038/nature05236 · 2006 · External reference
Drug resistance in glioblastoma: amini review
10.1007/s11064-011-0701-1 · 2012 · External reference
The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype
10.4161/cc.8.20.9701 · 2009 · External reference
A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2α
10.1093/brain/awq042 · 2010 · External reference
EphB2 receptor controls proliferation/migration dichotomy of glioblastoma by interacting with focal adhesion kinase
10.1038/onc.2012.16 · 2012 · External reference
MET signalling: principles and functions in development, organ regeneration and cancer
10.1038/nrm3012 · 2010 · External reference
Scatter factor/hepatocyte growth factor in brain tumor growth and angiogenesis
10.1215/s1152851705000050 · 2005 · External reference
Met and hepatocyte growth factor/ scatter factor expression in human gliomas
1997 · External reference
The scatter factor/hepatocyte growth factor: c-met pathway in human embryonal central nervous system tumor malignancy
10.1158/0008-5472.can-05-1946 · 2005 · External reference
Systemic anti-hepatocyte growth factor monoclonal antibody therapy induces the regression of intracranial glioma xenografts
10.1158/1078-0432.ccr-05-1793 · 2006 · External reference
A novel one-armed anti-c-Met antibody inhibits glioblastoma growth in vivo
10.1158/1078-0432.ccr-05-1418 · 2006 · External reference
The MET oncogene is a functional marker of a glioblastoma stem cell subtype
10.1158/0008-5472.can-11-3490 · 2012 · External reference
MET signaling regulates glioblastoma stem cells
10.1158/0008-5472.can-11-3760 · 2012 · External reference
c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype
10.1073/pnas.1016912108 · 2011 · External reference
Contrasting in vivo and in vitro fates of glioblastoma cell subpopulations with amplified EGFR
10.1002/gcc.10300 · 2004 · External reference
Neurosphere assays: growth factors and hormone differences in tumor and nontumor studies
10.1634/stemcells.2006-0399 · 2006 · External reference
Isolation of neural stem cells from neural tissues using the neurosphere technique
10.1002/9780470151808.sc02d06s15 · 2010 · External reference
Kruppel-like family of transcription factor 9, a differentiation-associated transcription factor, suppresses Notch1 signaling and inhibits glioblastoma-initiating stem cells
10.1002/stem.561 · 2011 · External reference
Establishment, maintenance and in vitro and in vivo applications of primary human glioblastoma multiforme (GBM) xenograft models for translational biology studies and drug discovery
10.1002/0471141755.ph1416s52 · 2011 · External reference
EGFRvIII and c-Met pathway inhibitors synergize against PTEN-null/EGFRvIII+ glioblastoma xenografts
10.1158/1535-7163.mct-09-0188 · 2009 · External reference
Targeting the c-Met pathway potentiates glioblastoma responses to γ-radiation
10.1158/1078-0432.ccr-05-0166 · 2005 · External reference
New strategy for the analysis of phenotypic marker antigens in brain tumor-derived neurospheres in mice and humans
10.3171/foc/2008/24/3-4/e27 · 2008 · External reference
Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma
10.1158/0008-5472.can-04-1364 · 2004 · External reference
DNER, an epigenetically modulated gene, regulates glioblastoma-derived neurosphere cell differentiation and tumor propagation
10.1002/stem.89 · 2009 · External reference
Fully human monoclonal antibodies to hepatocyte growth factor with therapeutic potential against hepatocyte growth factor/ c-Met-dependent human tumors
10.1158/0008-5472.can-05-3329 · 2006 · External reference
Hepatocyte growth factor (HGF) autocrine activation predicts sensitivity to MET inhibition in glioblastoma
10.1073/pnas.1119059109 · 2012 · External reference
The plasticity of oncogene addiction: implications for targeted therapies directed to receptor tyrosine kinases
10.1593/neo.09230 · 2009 · External reference
Cancer stem cells: distinct entities or dynamically regulated phenotypes?
10.1158/0008-5472.can-11-3070 · 2012 · External reference
Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells
10.1016/j.stem.2010.01.001 · 2010 · External reference
Autocrine TGF-β signaling maintains tumorigenicity of glioma-initiating cells through Sry-related HMG-box factors
10.1016/j.stem.2009.08.018 · 2009 · External reference
Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells
10.1073/pnas.1106645108 · 2011 · External reference
Integrin alpha 6 regulates glioblastoma stem cells
10.1016/j.stem.2010.02.018 · 2010 · External reference
