Research graph
References from mRNA Expression Profiles for Prostate Cancer following Fractionated Irradiation Are Influenced by p53 Status. Local targets link to admitted publications; unresolved targets remain external evidence.
Cancer statistics, 2010
2010 · External reference
A competing-risks analysis of survival after alternative treatment modalities for prostate cancer patients: 1988–2006
10.1016/j.eururo.2010.10.003 · 2011 · External reference
Gene expression profiles of normal human fibroblasts after exposure to ionizing radiation: a comparative study of low and high doses
10.1667/rr3354 · 2005 · External reference
Transcription factors activated in mammalian cells after clinically relevant doses of ionizing radiation
10.1038/sj.onc.1206680 · 2003 · External reference
Differential responses of stress genes to low dose-rate γ irradiation
2003 · External reference
Fractionated radiation therapy can induce a molecular profile for therapeutic targeting
10.1667/rr2105.1 · 2010 · External reference
Clinical implications of the p53 tumor-suppressor gene
10.1056/nejm199310283291807 · 1993 · External reference
p53, guardian of the genome
10.1038/358015a0 · 1992 · External reference
p53 in health and disease
10.1038/nrm2147 · 2007 · External reference
p53 function and dysfunction
10.1016/0092-8674(92)90421-8 · 1992 · External reference
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
10.1016/0092-8674(93)90719-7 · 1993 · External reference
p53 status and the efficacy of cancer therapy in vivo
10.1126/science.7973635 · 1994 · External reference
Wild-type p53 is a cell cycle checkpoint determinant following irradiation
10.1073/pnas.89.16.7491 · 1992 · External reference
Tumor-suppressor p53: implications for tumor development and prognosis
10.1200/jco.1998.16.9.3158 · 1998 · External reference
Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life
1988 · External reference
The tumor suppressor p53 modifies mutational processes in a human lymphoblastoid cell line
10.1016/s0027-5107(96)00193-5 · 1997 · External reference
Surfing the p53 network
10.1038/35042675 · 2000 · External reference
The hypoxic inducible stress response as a target for cancer drug discovery
10.1053/j.seminoncol.2006.04.011 · 2006 · External reference
Regulation of DNA repair in hypoxic cancer cells
10.1007/s10555-007-9061-3 · 2007 · External reference
Hypoxic regulation of mRNA expression
10.4161/cc.7.13.6203 · 2008 · External reference
Hypoxia induces a novel signature of chromatin modifications and global repression of transcription
10.1016/j.mrfmmm.2008.01.001 · 2008 · External reference
Gene expression profiling of breast, prostate, and glioma cells following single versus fractionated doses of radiation
10.1158/0008-5472.can-06-4250 · 2007 · External reference
Microarray analysis of radiation response genes in primary human fibroblasts
10.1016/j.ijrobp.2006.08.004 · 2006 · External reference
Gene expression profiles in human lymphocytes irradiated in vitro with low doses of gamma rays
10.1667/rr0487.1 · 2007 · External reference
Analysis of gene-expression profiles after gamma irradiation of normal human fibroblasts
10.1016/j.ijrobp.2005.08.030 · 2006 · External reference
Low-dose exposure to gamma rays induces specific gene regulations in normal human keratinocytes
10.1667/rr3391 · 2005 · External reference
Wild-type p53 suppresses growth of human prostate cancer cells containing mutant p53 alleles
1991 · External reference
NS-398, ibuprofen, and cyclooxygenase-2 RNA interference produce significantly different gene expression profiles in prostate cancer cells
10.1158/1535-7163.mct-08-0928 · 2009 · External reference
Fractionated radiation alters oncomir and tumor suppressor miRNAs in human prostate cancer cells
10.1667/rr2703.1 · 2012 · External reference
Dose- and time-dependent changes in gene expression in human glioma cells after low radiation doses
10.1667/rr0940.1 · 2007 · External reference
The efficacy of radiotherapy relies upon induction of type I interferon-dependent innate and adaptive immunity
10.1158/0008-5472.can-10-2820 · 2011 · External reference
Synergistic antitumor activity of immune strategies combined with radiation
10.2741/2436 · 2007 · External reference
Radiation survivors: understanding and exploiting the phenotype following fractionated radiation therapy
10.1158/1541-7786.mcr-12-0492 · 2013 · External reference
Hyper-fractionated conformal radiotherapy in locally advanced prostate cancer: results of a dose escalation study
10.1016/0360-3016(95)02202-3 · 1996 · External reference
Is the alpha-beta ratio of prostate cancer really low? A prospective, non-randomized trial comparing standard and hyperfractionated conformal radiation therapy
10.1016/j.radonc.2004.12.019 · 2005 · External reference
Low-dose fractionated radiation as a chemopotentiator of neoadjuvant paclitaxel and carboplatin for locally advanced squamous cell carcinoma of the head and neck: results of a new treatment paradigm
10.1016/j.ijrobp.2003.09.019 · 2004 · External reference
Low-dose radiotherapy as a chemopotentiator of gemcitabine in tumors of the pancreas or small bowel: a phase I study exploring a new treatment paradigm
10.1016/j.ijrobp.2006.11.045 · 2007 · External reference
Low-dose abdominal radiation as a docetaxel chemosensitizer for recurrent epithelial ovarian cancer: a phase I study of the Gynecologic Oncology Group
10.1016/j.ygyno.2010.10.018 · 2011 · External reference
Human tumor cells segregate into radiosensitivity groups that associate with ATM and TP53 status
10.1080/02841860601080407 · 2007 · External reference
P53 abnormalities and outcomes in colorectal cancer: a systematic review
10.1038/sj.bjc.6602358 · 2005 · External reference
Role of p53 mutations, protein function and DNA damage for the radiosensitivity of human tumour cells
10.1080/09553000310001642902 · 2004 · External reference
Clinico-pathological significance of nuclear accumulation of tumor suppressor gene p53 product in primary lung cancer
10.1111/j.1349-7006.1992.tb02358.x · 1992 · External reference
Functional p53 increases prostate cancer cell survival after exposure to fractionated doses of ionizing radiation
2003 · External reference
Elevated levels of prostate-specific antigen (PSA) in prostate cancer cells expressing mutant p53 is associated with tumor metastasis
10.1002/mc.10154 · 2003 · External reference
p53 protein accumulation and gene mutation in the progression of human prostate carcinoma
10.1093/jnci/85.20.1657 · 1993 · External reference
The role of p53 in radiation therapy outcomes for favorable-to-intermediate-risk prostate cancer
10.1016/s0360-3016(02)02781-5 · 2002 · External reference
Expression of Bcl-2, p53, and MDM2 in localized prostate cancer with respect to the outcome of radical radiotherapy dose escalation
10.1016/j.ijrobp.2009.07.1728 · 2010 · External reference
p53 status and prognosis of locally advanced prostatic adenocarcinoma: a study based on RTOG 8610
10.1093/jnci/89.2.158 · 1997 · External reference
p53 protein expression status and recurrence in men treated with radiation and androgen suppression therapy for higher-risk prostate cancer: a prospective phase II Cancer and Leukemia Group B Study (CALGB 9682)
10.1016/j.urology.2007.11.005 · 2008 · External reference
RTOG Prognostic value of abnormal p53 expression in locally advanced prostate cancer treated with androgen deprivation and radiotherapy: a study based on RTOG9202
10.1016/j.ijrobp.2007.04.070 · 2007 · External reference
p53 gene alterations in prostate cancer after radiation failure and their association with clinical outcome: a molecular and immunohistochemical analysis
10.1016/s0344-0338(99)80024-7 · 1999 · External reference
The cytotoxicity of chemotherapy drugs varies in cervical cancer cells depending on the p53 status
10.4161/cbt.3.11.1340 · 2004 · External reference
p53 mutation status predicts pathological response to chemoradiotherapy in locally advanced esophageal cancer
10.1245/s10434-009-0786-9 · 2010 · External reference
Histopathological changes induced by therapies in the benign prostate and prostate adenocarcinoma
2007 · External reference
Radiation induces p53-dependent cell apoptosis in bladder cancer cells with wild-type-p53 but not in p53-mutated bladder cancer cells
10.1007/s00240-003-0355-9 · 2003 · External reference
Adenoviral-mediated p53 transgene expression sensitizes both wild-type and null p53 prostate cancer cells in vitro to radiation
10.1016/s0360-3016(00)01409-7 · 2000 · External reference
Low-dose irradiation alters the transcript profiles of human lymphoblastoid cells including genes associated with cytogenetic radioadaptive response
10.1667/rr3356.1 · 2005 · External reference
Prostate cancer radiosensitization in vivo with adenovirus-mediated p53 gene therapy
2000 · External reference
Microarray analysis of the transcriptional response to single or multiple doses of ionizing radiation in human subcutaneous fibroblasts
2005 · External reference
Linking radiation oncology and imaging through molecular biology (or now that therapy and diagnosis have separated, it's time to get together again!)
10.1148/radiol.2281021567 · 2003 · External reference
The concept of synthetic lethality in the context of anticancer therapy
10.1038/nrc1691 · 2005 · External reference
Principles of cancer therapy: oncogene and non-oncogene addiction
10.1016/j.cell.2009.02.024 · 2009 · External reference