References

Immunity, inflammation, and cancer

10.1016/j.cell.2010.01.025 · 2010 · External reference

Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability

10.1093/carcin/bgp127 · 2009 · External reference

Macrophage diversity enhances tumor progression and metastasis

10.1016/j.cell.2010.03.014 · 2010 · External reference

Mast cells are an essential hematopoietic component for polyp development

10.1073/pnas.0704620104 · 2007 · External reference

A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

10.1038/nm.2015 · 2009 · External reference

Targeting natural killer cells and natural killer T cells in cancer

10.1038/nri3174 · 2012 · External reference

Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells

10.1016/j.ccr.2009.07.015 · 2009 · External reference

Adenomalinked barrier defects and microbial products drive IL-23/IL-17-mediated tumour growth

10.1038/nature11465 · 2012 · External reference

T-regulatory cells shift from a protective anti-inflammatory to a cancer-promoting proinflammatory phenotype in polyposis

10.1158/0008-5472.can-09-0304 · 2009 · External reference

CD4+CD25+ regulatory lymphocytes induce regression of intestinal tumors in ApcMin/+ mice

10.1158/0008-5472.can-04-3104 · 2005 · External reference

Wnt signaling in macrophages: augmenting and inhibiting mycobacteria-induced inflammatory responses

10.1016/j.ejcb.2010.11.004 · 2011 · External reference

Wnt/β-catenin signaling and disease

10.1016/j.cell.2012.05.012 · 2012 · External reference

Macro-phages in tumor microenvironments and the progression of tumors

10.1155/2012/948098 · 2012 · External reference

Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity

10.1172/jci200519229 · 2005 · External reference

A bacterial driver-passenger model for colorectal cancer: beyond the usual suspects

10.1038/nrmicro2819 · 2012 · External reference

Extracellular superoxide production by Enterococcus faecalis promotes chromosomal instability in mammalian cells

10.1053/j.gastro.2006.11.040 · 2007 · External reference

Enterococcus faecalis induces aneuploidy and tetraploidy in colonic epithelial cells through a bystander effect

10.1158/0008-5472.can-08-1551 · 2008 · External reference

Celecoxib for the prevention of sporadic colorectal adenomas

10.1056/nejmoa061355 · 2006 · External reference

The role of aspirin in cancer prevention

10.1038/nrclinonc.2011.199 · 2012 · External reference

Mechanism of radiation-induced bystander effect: role of the cyclooxygenase-2 signaling pathway

10.1073/pnas.0505473102 · 2005 · External reference

Prostaglandins and cancer

10.1136/gut.2004.047100 · 2006 · External reference

Cyclooxygenase- and lipoxygenase-mediated DNA damage

10.1007/s10555-011-9298-8 · 2011 · External reference

Cyclooxygenase-2 generates the endogenous mutagen trans-4-hydroxy-2-nonenal in Enterococcus faecalis-infected macrophages

10.1158/1940-6207.capr-12-0350 · 2013 · External reference

4-Hydroxy-2-nonenal mediates genotoxicity and bystander effects caused by Enterococcus faecalis-infected macrophages

10.1053/j.gastro.2011.11.020 · 2012 · External reference

Trans-4-hydroxy-2-nonenal inhibits nucleotide excision repair in human cells: a possible mechanism for lipid peroxidation-induced carcinogenesis

10.1073/pnas.0402794101 · 2004 · External reference

A lipid peroxidation-derived inflammatory mediator: identification of 4-hydroxy-2-nonenal as a potential inducer of cyclooxygenase-2 in macrophages

10.1074/jbc.m409935200 · 2004 · External reference

Localization of cyclooxygenase-2 in human sporadic colorectal adenomas

10.1016/s0002-9440(10)64759-1 · 2000 · External reference

Frequent nitric oxide synthase-2 expression in human colon adenomas: implication for tumor angiogenesis and colon cancer progression

1998 · External reference

Tumor necrosis factor-α is a potent endogenous mutagen that promotes cellular transformation

10.1158/0008-5472.can-06-2540 · 2006 · External reference

TNF-α mediates macrophage-induced bystander effects through netrin-1

10.1158/0008-5472.can-12-1463 · 2012 · External reference

Netrin-1 and its dependence receptors as original targets for cancer therapy

10.1097/cco.0b013e328333dcd1 · 2010 · External reference

Netrin-1 up-regulation in inflammatory bowel diseases is required for colorectal cancer progression

10.1073/pnas.0901767106 · 2009 · External reference

Netrin-1 controls colorectal tumorigenesis by regulating apoptosis

10.1038/nature02788 · 2004 · External reference

Interleukin10-deficient mice develop chronic enterocolitis

10.1016/0092-8674(93)80068-p · 1993 · External reference

Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approach

10.1038/sj.bjc.6603240 · 2006 · External reference

Suppression of experimental colitis by intestinal mononuclear phagocytes

10.1189/jlb.1205734 · 2006 · External reference

Clodronate and liposome-encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5′-(β, γ-dichloromethylene) triphosphate, by mammalian cells in vitro

10.1359/jbmr.1997.12.9.1358 · 1997 · External reference

Exposure to oral bisphosphonates and risk of cancer

10.1002/ijc.27389 · 2012 · External reference

Reduced risk of colorectal cancer with use of oral bisphosphonates: a systematic review and meta-analysis

10.1200/jco.2012.42.9530 · 2013 · External reference

Enterococcus faecalis produces extracellular superoxide and hydrogen peroxide that damages colonic epithelial cell DNA

10.1093/carcin/23.3.529 · 2002 · External reference

Large scale variation in Enterococcus faecalis illustrated by the genome analysis of strain OG1RF

10.1186/gb-2008-9-7-r110 · 2008 · External reference

Enhancement of human intestinal mast cell mediator release in active ulcerative colitis

10.1016/0016-5085(90)91238-2 · 1990 · External reference

Histamine release from gut mast cells from patients with inflammatory bowel diseases

10.1136/gut.31.7.791 · 1990 · External reference

Mast cell 5-lipoxygenase activity promotes intestinal polyposis in APCΔ468 mice

10.1158/0008-5472.can-10-1923 · 2011 · External reference

Macrophage inflammatory protein-1 alpha and monocyte chemoattractant peptide-1 elicit immediate and late cutaneous reactions and activate murine mast cells in vivo

10.4049/jimmunol.152.3.1298 · 1994 · External reference

Radiation-induced genomic instability and bystander effects: related inflammatory-type responses to radiation-induced stress and injury? A review

10.1080/0955300021000045664 · 2003 · External reference

Long-term exposure of colonic epithelial cells to Enterococcus faecalis-infected macrophages causes cellular transformation

2011 · External reference

Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12- and gamma interferon-dependent mechanism

10.1128/iai.66.11.5157-5166.1998 · 1998 · External reference

Variable phenotypes of enterocolitis in interleukin 10-deficient mice monoassociated with two different commensal bacteria

10.1053/j.gastro.2005.02.009 · 2005 · External reference

Nitric oxide signaling in colon cancer chemoprevention

10.1016/j.mrfmmm.2004.05.022 · 2004 · External reference

Ibadronate may prevent colorectal carcinogenesis in mice with ulcerative colitis

2009 · External reference

Elimination of local macro-phages in intestine prevents chronic colitis in interleukin-10-deficient mice

10.1023/a:1021960401290 · 2003 · External reference

APC, signal transduction and genetic instability in colorectal cancer

10.1038/35094067 · 2001 · External reference

Decreased expression of CD44, alpha-catenin, and deleted colon carcinoma and altered expression of beta-catenin in ulcerative colitis-associated dysplasia and carcinoma, as compared with sporadic colon neoplasms

10.1002/1097-0142(20000815)89:4<733::aid-cncr3>3.0.co;2-# · 2000 · External reference

The role of the transcription factor AP-1 in colitis-associated and β-catenindependent intestinal tumorigenesis in mice

10.1038/onc.2008.211 · 2008 · External reference

Enhanced colitis-associated colon carcinogenesis in a novel Apc mutant rat

10.1111/j.1349-7006.2009.01287.x · 2009 · External reference

Expression of tight and adherens junction proteins in ulcerative colitis associated colorectal carcinoma: upregulation of claudin-1, claudin-3, claudin-4, and β-catenin

10.1007/s00384-009-0653-y · 2009 · External reference

Cyclooxygenase-2 and colorectal cancer chemoprevention: the β-catenin connection

10.1158/0008-5472.can-06-2233 · 2006 · External reference

Activated macrophages promote Wnt signalling through tumour necrosis factor-α in gastric tumour cells

10.1038/emboj.2008.105 · 2008 · External reference

Mast cell progenitor trafficking and maturation

10.1007/978-1-4419-9533-9_2 · 2011 · External reference

Role of mast cells in inflammatory bowel disease and inflammation-associated colorectal neoplasia in IL-10-deficient mice

10.1371/journal.pone.0012220 · 2010 · External reference

Characterization of colonic and mesenteric lymph node dendritic cell sub-populations in a murine adoptive transfer model of inflammatory bowel disease

10.1097/00054725-200411000-00018 · 2004 · External reference

Interleukin-10 ablation promotes tumor development, growth, and metastasis

10.1158/0008-5472.can-10-4627 · 2012 · External reference

Enterococcus faecalis induces inflammatory bowel disease in interleukin-10 knockout mice

10.1016/s0002-9440(10)61172-8 · 2002 · External reference

Extracellular superoxide production by Enterococcus faecalis requires demethylmenaquinone and is attenuated by functional terminal quinol oxidases

10.1046/j.1365-2958.2001.02638.x · 2001 · External reference

Prospective case-cohort study of intestinal colonization with enterococci that produce extracellular superoxide and the risk for colorectal adenomas or cancer

10.1111/j.1572-0241.1998.00710.x · 1998 · External reference

Real-time polymerase chain reaction quantification of specific butyrateproducing bacteria, Desulfovibrio and Enterococcus faecalis in the feces of patients with colorectal cancer

10.1111/j.1440-1746.2008.05490.x · 2008 · External reference

Novel observations of genotypic and metabolic characteristics of three subspecies of Streptococcus gallolyticus

10.1128/jcm.42.10.4912-4913.2004 · 2004 · External reference

Serological investigation into the association between Streptococcus bovis and colonic cancer

10.1136/jcp.46.12.1116 · 1993 · External reference

NF-kappaB, p38 MAPK and JNK are highly expressed and active in the stroma of human colonic adenomatous polyps

10.1038/sj.onc.1204162 · 2001 · External reference

Influence of interleukin-8 and interleukin-10 on sporadic colon cancer development and progression

10.1093/carcin/bgn164 · 2008 · External reference

Rapid development of colitis in NSAID-treated IL-10-deficient mice

10.1053/gast.2002.1231527 · 2002 · External reference

Microbial modulation of innate defense: goblet cells and the intestinal mucus layer

10.1093/ajcn/73.6.1131s · 2001 · External reference

Intestinal inflammation targets cancer-inducing activity of the microbiota

10.1126/science.1224820 · 2012 · External reference