Research graph
References from Temporal Macrophage Activation Is Reduced by CCR2 Knockout in a Murine Subacromial Impingement Model. Local targets link to admitted publications; unresolved targets remain external evidence.
A systematic review and pooled analysis of the prevalence of rotator cuff disease with increasing age
10.1016/j.jse.2014.08.001 · 2014 · External reference
Shoulder disorders in general practice: incidence, patient characteristics, and management
10.1136/ard.54.12.959 · 1995 · External reference
Injection Therapies for Rotator Cuff Disease
10.1016/j.ocl.2017.11.010 · 2018 · External reference
Management of Rotator Cuff Injuries
10.5435/jaaos-d-19-00463 · 2020 · External reference
Mechanisms of rotator cuff tendinopathy: intrinsic, extrinsic, or both?
10.1016/j.clinbiomech.2010.08.001 · 2011 · External reference
Subacromial impingement syndrome
10.5435/00124635-201111000-00006 · 2011 · External reference
Increased levels of inflammatory markers in the subscapularis tendon and joint capsule in patients with subacromial impingement
10.1007/s00167-020-05992-9 · 2021 · External reference
Identification of Inflammatory Mediators in Tendinopathy Using a Murine Subacromial Impingement Model
10.1002/jor.24434 · 2019 · External reference
Immunohistochemical features of rotator cuff tendinopathy
10.1093/bmb/ldz016 · 2019 · External reference
Macrophage plasticity, polarization, and function in health and disease
10.1002/jcp.26429 · 2018 · External reference
Editorial Commentary: Suppression of Inflammatory Macrophages Is a Potential Strategy to Improve Rotator Cuff Healing and Has Shown Promise in Preclinical Models
10.1016/j.arthro.2024.12.036 · 2025 · External reference
The role of the macrophage in tendinopathy and tendon healing
10.1002/jor.24667 · 2020 · External reference
Modulating Macrophage Polarization through CCR2 Inhibition and Multivalent Engagement
10.1021/acs.molpharmaceut.8b00237 · 2018 · External reference
CCR2- and CCR2+ corneal macrophages exhibit distinct characteristics and balance inflammatory responses after epithelial abrasion
10.1038/mi.2016.139 · 2017 · External reference
Effect of CCR2 Knockout on Tendon Biomechanical Properties in a Mouse Model of Delayed Rotator Cuff Repair
10.2106/jbjs.22.01160 · 2023 · External reference
Pharmacological antagonism of Ccr2+ cell recruitment to facilitate regenerative tendon healing
10.1002/jor.25986 · 2025 · External reference
Evaluating the role of subacromial impingement in rotator cuff tendinopathy: Development and analysis of a novel murine model
10.1002/jor.24026 · 2018 · External reference
Targeting the tumor-associated folate receptor with an 111In-DTPA conjugate of pteroic acid
10.1021/ja043006n · 2005 · External reference
A functional folate receptor is induced during macrophage activation and can be used to target drugs to activated macrophages
10.1182/blood-2008-04-150789 · 2009 · External reference
Radiosynthesis and preclinical evaluation of [68Ga]Ga-NOTA-folate for PET imaging of folate receptor β-positive macrophages
10.1038/s41598-020-70394-3 · 2020 · External reference
Distinct Gene Expression Profile in Patients With Poor Postoperative Outcomes After Rotator Cuff Repair: A Case-Control Study
10.1177/03635465211023212 · 2021 · External reference
Failed healing of rotator cuff repair correlates with altered collagenase and gelatinase in supraspinatus and subscapularis tendons
10.1177/0363546512456519 · 2012 · External reference
Glucocorticoids inhibit macrophage differentiation towards a pro-inflammatory phenotype upon wounding without affecting their migration
10.1242/dmm.037887 · 2019 · External reference
Liposomal targeting of prednisolone phosphate to synovial lining macrophages during experimental arthritis inhibits M1 activation but does not favor M2 differentiation
10.1371/journal.pone.0054016 · 2013 · External reference
Corticosteroid Injections Give Small and Transient Pain Relief in Rotator Cuff Tendinosis: A Meta-analysis
10.1007/s11999-016-5002-1 · 2017 · External reference
Temporary inductions of matrix metalloprotease-3 (MMP-3) expression and cell apoptosis are associated with tendon degeneration or rupture after corticosteroid injection
10.1002/jor.22681 · 2014 · External reference
Human Rotator Cuff Tears Reveal an Age-Dependent Increase in Markers of Cellular Senescence and Selective Removal of Senescent Cells With Dasatinib + Quercetin Increases Genetic Expression of COL1A1 In Vitro
10.1016/j.arthro.2023.05.036 · 2024 · External reference
Healthy Tendon Stem Cell-Derived Exosomes Promote Tendon-To-Bone Healing of Aged Chronic Rotator Cuff Tears by Breaking the Positive-Feedback Cross-Talk between Senescent Tendon Stem Cells and Macrophages through the Modulation of Macrophage Polarization
10.1002/smll.202311033 · 2024 · External reference
CCR2 is expressed by tendon resident macrophage and T cells, while CCR2 deficiency impairs tendon healing via blunted involvement of tendon-resident and circulating monocytes/macrophages
10.1096/fj.202201162r · 2022 · External reference
