Research graph
References from Low back pain, disability, and biological aging: routinely measurable clinical clocks versus epigenetic clocks (NHANES). Local targets link to admitted publications; unresolved targets remain external evidence.
Global, regional, and national burden of low back pain, 1990–2020, its attributable risk factors, and projections to 2050
10.1016/s2665-9913(23)00098-x · 2023 · External reference
Report of the NIH Task Force on research standards for chronic low back pain
10.1007/s00586-014-3540-3 · 2014 · External reference
The impact of frailty and sarcopenia on postoperative outcomes in adult spine surgery: a systematic review
10.1016/j.spinee.2018.07.008 · 2018 · External reference
Frailty index is a significant predictor of complications and mortality after surgery for adult spinal deformity
10.1097/brs.0000000000001886 · 2016 · External reference
The hallmarks of aging
10.1016/j.cell.2013.05.039 · 2013 · External reference
An epigenetic biomarker of aging for lifespan and healthspan
10.18632/aging.101414 · 2018 · External reference
The pace of biological aging predicts nonspecific chronic low back pain severity
10.1016/j.jpain.2023.10.018 · 2024 · External reference
Epigenetic age biomarkers and risk assessment in adult spinal deformity: a novel association of biological age with frailty and disability
10.3171/2023.10.spine23435 · 2024 · External reference
High-impact chronic pain and epigenetic aging: findings from the Health and Retirement Study
10.1093/gerona/glae149 · 2024 · External reference
The role of lifestyle behaviors in shaping the relationship between chronic pain and epigenetic age acceleration: evidence from NHANES 1998 to 2002
10.2147/jpr.s521606 · 2025 · External reference
A new approach to the concept and computation of biological age
10.1016/j.mad.2005.10.004 · 2006 · External reference
A toolkit for quantification of biological age from blood chemistry and organ function test data: BioAge
10.1007/s11357-021-00480-5 · 2021 · External reference
DNA methylation age of human tissues and cell types
10.1186/gb-2013-14-10-r115 · 2013 · External reference
Genome-wide methylation profiles reveal quantitative views of human aging rates
10.1016/j.molcel.2012.10.016 · 2013 · External reference
DNA methylation GrimAge strongly predicts lifespan and healthspan
10.18632/aging.101684 · 2019 · External reference
Quantification of the pace of biological aging in humans through a blood test, the DunedinPoAm DNA methylation algorithm
10.7554/elife.54870 · 2020 · External reference
DNA methylation-based measures of biological age: meta-analysis predicting time to death
10.18632/aging.101020 · 2016 · External reference
National Health and Nutrition Examination Survey: analytic guidelines, 1999–2010
2013 · External reference
Sensitivity analysis in observational research: introducing the E-value
10.7326/m16-2607 · 2017 · External reference
Epigenetic age acceleration and mortality risk prediction in US adults
10.1007/s11357-025-01604-x · 2025 · External reference
Aging acceleration, not chronological age, is associated with cognitive performance in older adults: a cross-sectional study on the protective role of physical activity
10.1097/md.0000000000043431 · 2025 · External reference
Accelerated cellular senescence in degenerate intervertebral discs: a possible role in the pathogenesis of intervertebral disc degeneration
10.1186/ar2198 · 2007 · External reference
The relationship between muscle mass and low back pain: a cross-sectional study
10.1007/s00586-025-09026-1 · 2025 · External reference
What low back pain is and why we need to pay attention
10.1016/s0140-6736(18)30480-x · 2018 · External reference
The characterization of frailty in spine surgery: a systematic review of frailty indices
10.1007/s00586-025-09159-3 · 2025 · External reference
