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References from Integrated single-cell transcriptomic analysis reveals KLF6-associated macrophage-alveolar epithelial crosstalk in sepsis-associated acute lung injury. Local targets link to admitted publications; unresolved targets remain external evidence.
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) [J]
10.1001/jama.2016.0287 · 2016 · External reference
Sepsis-Induced Acute Lung Injury Is Alleviated by Small Molecules from Dietary Plants via Pyroptosis Modulation [J]
10.1021/acs.jafc.2c08926 · 2023 · External reference
Mortality rates for patients with acute lung injury/ARDS have decreased over time [J]
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10.1038/s41572-019-0069-0 · 2019 · External reference
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10.1007/s00134-020-06296-9 · 2020 · External reference
Endocan, sepsis, pneumonia, and acute respiratory distress syndrome [J]
10.1186/s13054-018-2222-7 · 2018 · External reference
Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries [J]
10.1001/jama.2016.0291 · 2016 · External reference
Regulation of alveolar macrophage death in acute lung inflammation [J]
10.1186/s12931-018-0756-5 · 2018 · External reference
The role of macrophages polarization in sepsis-induced acute lung injury [J]
10.3389/fimmu.2023.1209438 · 2023 · External reference
Histone methyltransferase SETD2 inhibits M1 macrophage polarization and glycolysis by suppressing HIF-1alpha in sepsis-induced acute lung injury [J]
10.1007/s00430-023-00778-5 · 2023 · External reference
Nicotinamide mononucleotide alleviates endotoxin-induced acute lung injury by modulating macrophage polarization via the SIRT1/NF-kappaB pathway [J]
10.1080/13880209.2023.2292256 · 2024 · External reference
TET1-Mediated DNA hydroxymethylation of KLF6 promotes LPS-induced pulmonary fibrosis by activating the S1PR3/RhoA/ROCK signaling pathway [J]
10.1186/s12931-025-03425-0 · 2025 · External reference
Integrating bulk and single-cell sequencing reveals the phenotype-associated cell subpopulations in sepsis-induced acute lung injury [J]
10.3389/fimmu.2022.981784 · 2022 · External reference
Single-cell transcriptomics to explore the immune system in health and disease [J]
10.1126/science.aan6828 · 2017 · External reference
Dictionary learning for integrative, multimodal and scalable single-cell analysis [J]
10.1038/s41587-023-01767-y · 2024 · External reference
Doublet identification in single-cell sequencing data using scDblFinder [J]
2021 · External reference
scCDC: a computational method for gene-specific contamination detection and correction in single-cell and single-nucleus RNA-seq data [J]
10.1186/s13059-024-03284-w · 2024 · External reference
Decontamination of ambient RNA in single-cell RNA-seq with DecontX [J]
10.1186/s13059-020-1950-6 · 2020 · External reference
CellMarker 2.0: an updated database of manually curated cell markers in human/mouse and web tools based on scRNA-seq data [J]
10.1093/nar/gkac947 · 2023 · External reference
decoupleR: ensemble of computational methods to infer biological activities from omics data [J]
10.1093/bioadv/vbac016 · 2022 · External reference
GSEApy: a comprehensive package for performing gene set enrichment analysis in Python [J]
10.1093/bioinformatics/btac757 · 2023 · External reference
Diffusion pseudotime robustly reconstructs lineage branching [J]
10.1038/nmeth.3971 · 2016 · External reference
hdWGCNA identifies co-expression networks in high-dimensional transcriptomics data [J]
10.1016/j.crmeth.2023.100498 · 2023 · External reference
Inference of Gene Regulatory Network from Single-Cell Transcriptomic Data Using pySCENIC [J]
10.1007/978-1-0716-1534-8_10 · 2021 · External reference
LIANA+ provides an all-in-one framework for cell-cell communication inference [J]
10.1038/s41556-024-01469-w · 2024 · External reference
Metascape provides a biologist-oriented resource for the analysis of systems-level datasets [J]
10.1038/s41467-019-09234-6 · 2019 · External reference
Unresolved reference
2018 · External reference
Unresolved reference
2022 · External reference
Kruppel-like transcription factor 6 regulates inflammatory macrophage polarization [J]
10.1074/jbc.m113.526749 · 2014 · External reference
IFIH1/IRF1/STAT1 promotes sepsis associated inflammatory lung injury via activating macrophage M1 polarization [J]
10.1016/j.intimp.2022.109478 · 2023 · External reference
Liensinine reduces acute lung injury brought on by lipopolysaccharide by inhibiting the activation of the NF-kappaB signaling pathway through modification of the Src/TRAF6/TAK1 axis [J]
10.1007/s10787-023-01368-w · 2024 · External reference
Defining the mechanism of galectin-3-mediated TGF-beta1 activation and its role in lung fibrosis [J]
10.1016/j.jbc.2024.107300 · 2024 · External reference
Alveolar epithelial type 2 cells in acute lung injury and acute respiratory distress syndrome: spatiotemporal fate and regulation [J]
10.1093/burnst/tkaf050 · 2025 · External reference
