Research graph
References from Clinicopathological and Genomic Analysis of Hepatoid Alpha-Fetoprotein-Producing Gastric Cancer with Concurrent Multiple Targetable Molecular Aberrations. Local targets link to admitted publications; unresolved targets remain external evidence.
Alpha fetoprotein (AFP)-producing gastric cancer: clinicopathological features and treatment strategies
10.1186/s13578-025-01424-8 · 2025 · External reference
Elevated Serum Alpha-Fetoprotein Is a Significant Prognostic Factor for Patients with Gastric Cancer: Results Based on a Large-Scale Retrospective Study
10.3389/fonc.2022.901061 · 2022 · External reference
Whole-exome sequencing of alpha-fetoprotein producing gastric carcinoma reveals genomic profile and therapeutic targets
10.1038/s41467-021-24170-0 · 2021 · External reference
Genomic landscape and potential therapeutic targets in alpha-fetoprotein-producing gastric cancer
10.1007/s10120-025-01594-x · 2025 · External reference
Significant response to PD-L1 inhibitor after resistance to PD-1 inhibitor in an advanced alpha-fetoprotein-positive gastric cancer
10.3389/fonc.2022.962126 · 2022 · External reference
Comprehensive molecular characterization of gastric adenocarcinoma
10.1038/nature13480 · 2014 · External reference
Clinicopathological features of tumor mutation burden, Epstein-Barr virus infection, microsatellite instability and PD-L1 status in Chinese patients with gastric cancer
10.1186/s13000-021-01099-y · 2021 · External reference
Expression and significance of EBV, ARID1A and PIK3CA in gastric carcinoma
10.3892/mmr.2019.9886 · 2019 · External reference
ARID1A in cancer: Friend or foe?
10.3389/fonc.2023.1136248 · 2023 · External reference
Somatic ARID1A mutation stratifies patients with PD-1 blockade and adjuvant chemotherapy
10.1007/s00262-022-03326-x · 2022 · External reference
Pan-cancer analysis of ARID family members as novel biomarkers for immune checkpoint inhibitor therapy
10.1080/15384047.2021.2011643 · 2022 · External reference
ARID1A deficiency reverses the response to anti-PD(L)1 therapy in EGFR-mutant lung adenocarcinoma by enhancing autophagy-inhibited type I interferon production
10.1186/s12964-022-00958-5 · 2022 · External reference
Targeting the PI3K and MAPK pathways to improve response to HER2-targeted therapies in HER2-positive gastric cancer
10.1186/s12967-021-02842-1 · 2021 · External reference
Molecular pathogenesis and novel therapeutic avenues in alpha-fetoprotein-producing gastric cancer
10.3389/fonc.2026.1814851 · 2026 · External reference
Signaling pathways and therapeutic interventions in gastric cancer
10.1038/s41392-022-01190-w · 2022 · External reference
EBV-miR-BART10-3p and EBV-miR-BART22 promote metastasis of EBV-associated gastric carcinoma by activating the canonical Wnt signaling pathway
10.1007/s13402-020-00538-0 · 2020 · External reference
A CRISPR/Cas9-Engineered ARID1A-Deficient Human Gastric Cancer Organoid Model Reveals Essential and Nonessential Modes of Oncogenic Transformation
10.1158/2159-8290.cd-20-1109 · 2021 · External reference
Ligand-dependent Wnt signaling promotes gastric cancer metastasis through hyaluronan expression in microenvironment
10.1038/s41467-026-69470-5 · 2026 · External reference
Combinational zimberelimab plus lenvatinib and chemotherapy for alpha-fetoprotein elevated, advanced gastric cancer patients (AFPGC): a phase 1 dose-escalation study
10.1007/s00262-024-03743-0 · 2024 · External reference
The KEYNOTE-811 trial of dual PD-1 and HER2 blockade in HER2-positive gastric cancer
10.1038/s41586-021-04161-3 · 2021 · External reference
Immune checkpoint inhibitors are effective in the treatment of Epstein-Barr virus-associated gastric cancer: A case report
10.1097/md.0000000000033377 · 2023 · External reference
α-Fetoprotein-positive hepatoid adenocarcinoma of the stomach and a new classification: A case report
10.3892/ol.2024.14717 · 2024 · External reference
Comprehensive Analysis of Genomic Alterations in Hepatoid Adenocarcinoma of the Stomach and Identification of Clinically Actionable Alterations
10.3390/cancers14163849 · 2022 · External reference
An unusual cause of significantly elevated blood alpha-fetoprotein levels: a case report and literature review
10.3389/fonc.2024.1393074 · 2024 · External reference
Spatiotemporal HER2 heterogeneity in AFP-producing gastric cancer: navigating long-term survival with molecularly-guided therapy in a refractory case
10.3389/fimmu.2025.1696069 · 2026 · External reference
Therapeutic Role of Synthetic Lethality in ARID1A-Deficient Malignancies
10.36401/jipo-22-37 · 2024 · External reference
Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers
10.1038/nm.3799 · 2015 · External reference
Molecular classification of gastric cancer: Towards a pathway-driven targeted therapy
10.18632/oncotarget.4990 · 2016 · External reference
