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References from From the Oral Microbiome to Periodontitis: Bioinformatics Identifies ANK3. Local targets link to admitted publications; unresolved targets remain external evidence.
The oral microbiome: diversity, biogeography and human health
10.1038/s41579-023-00963-6 · 2024 · External reference
Oral microbiome: a review of its impact on oral and systemic health
10.3390/microorganisms12091797 · 2024 · External reference
Burden of severe periodontitis and edentulism in 2021, with projections up to 2050: the Global Burden of Disease 2021 study
10.1111/jre.13337 · 2024 · External reference
Treating chronic periodontitis: current status, challenges, and future directions
10.2147/ccide.s7712 · 2010 · External reference
Oral bacterial community dynamics during induction of gingival inflammation
10.3389/fcimb.2025.1597690 · 2025 · External reference
Mendelian randomization
10.1038/s43586-021-00092-5 · 2022 · External reference
METAL: fast and efficient meta-analysis of genomewide association scans
10.1093/bioinformatics/btq340 · 2010 · External reference
Metagenome-genome-wide association studies reveal human genetic impact on the oral microbiome
10.1038/s41421-021-00356-0 · 2021 · External reference
Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases
10.1038/s41588-020-0640-3 · 2020 · External reference
A cross-population atlas of genetic associations for 220 human phenotypes
10.1038/s41588-021-00931-x · 2021 · External reference
Diversity and scale: genetic architecture of 2068 traits in the VA Million Veteran Program
10.1126/science.adj1182 · 2024 · External reference
FinnGen provides genetic insights from a well-phenotyped isolated population
10.1038/s41586-022-05473-8 · 2023 · External reference
Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies
10.1038/s41588-018-0184-y · 2018 · External reference
Subgingival bacterial colonization profiles correlate with gingival tissue gene expression
10.1186/1471-2180-9-221 · 2009 · External reference
Single-cell RNA landscape of the osteoimmunology microenvironment in periodontitis
10.7150/thno.65694 · 2022 · External reference
Spatially resolved transcriptomics reveals pro-inflammatory fibroblast involved in lymphocyte recruitment through CXCL8 and CXCL10
10.7554/elife.81525 · 2023 · External reference
The 1000 Chinese Pangenome empowers medical and population genetics
10.1038/s41586-026-10315-y · 2026 · External reference
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
10.1038/s41588-021-00913-z · 2021 · External reference
Single-cell Mayo Map (scMayoMap): an easy-to-use tool for cell type annotation in single-cell RNA-sequencing data analysis
10.1186/s12915-023-01728-6 · 2023 · External reference
Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data
10.1038/s41587-021-01091-3 · 2022 · External reference
Robust decomposition of cell type mixtures in spatial transcriptomics
10.1038/s41587-021-00830-w · 2022 · External reference
Spatially resolved mapping of cells associated with human complex traits
10.1038/s41586-025-08757-x · 2025 · External reference
Microbiological and metabolomic analysis of biomarkers for grades A and B in stage II periodontitis
10.1007/s10753-025-02260-1 · 2025 · External reference
Machine learning reveals microbiome differences by periodontitis severity
10.1371/journal.pone.0349686 · 2026 · External reference
Spent culture supernatant of Streptococcus gordonii mitigates inflammation of human periodontal cells and inhibits proliferation of pathogenic oral microbes
10.1002/jper.22-0333 · 2023 · External reference
The oral microbiome in periodontal health
10.3389/fcimb.2021.629723 · 2021 · External reference
Akkermansia muciniphila inhibited the periodontitis caused by Fusobacterium nucleatum
10.1038/s41522-023-00417-0 · 2023 · External reference
Transcriptional activity of predominant Streptococcus species at multiple oral sites associate with periodontal status
10.3389/fcimb.2021.752664 · 2021 · External reference
Proteomic analysis of the periodontal pathogen Prevotella intermedia secretomes in biofilm and planktonic lifestyles
10.1038/s41598-022-09085-0 · 2022 · External reference
Porphyromonas gingivalis infection induces lipopolysaccharide and peptidoglycan penetration through gingival epithelium
10.3389/froh.2022.845002 · 2022 · External reference
Periodontitis: consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions
10.1111/jcpe.12946 · 2018 · External reference
Periodontal ligament stem cells in tissue remodeling: from mechanical forces to inflammatory signals
10.1186/s13287-025-04777-6 · 2025 · External reference
Periodontal inflammation-triggered by periodontal ligament stem cell pyroptosis exacerbates periodontitis
10.3389/fcell.2021.663037 · 2021 · External reference
Quercetin reverses TNF-α induced osteogenic damage to human periodontal ligament stem cells by suppressing the NF-κB/NLRP3 inflammasome pathway
10.3892/ijmm.2021.4872 · 2021 · External reference
Spent culture supernatant of Streptococcus gordonii mitigates inflammation of human periodontal cells and inhibits proliferation of pathogenic oral microbes
10.1002/jper.22-0333 · ExternalCitation · doi-reference
Microbiological and metabolomic analysis of biomarkers for grades A and B in stage II periodontitis
10.1007/s10753-025-02260-1 · ExternalCitation · doi-reference
Metagenome-genome-wide association studies reveal human genetic impact on the oral microbiome
10.1038/s41421-021-00356-0 · ExternalCitation · doi-reference
Akkermansia muciniphila inhibited the periodontitis caused by Fusobacterium nucleatum
10.1038/s41522-023-00417-0 · ExternalCitation · doi-reference
The oral microbiome: diversity, biogeography and human health
10.1038/s41579-023-00963-6 · ExternalCitation · doi-reference
FinnGen provides genetic insights from a well-phenotyped isolated population
10.1038/s41586-022-05473-8 · ExternalCitation · doi-reference
Spatially resolved mapping of cells associated with human complex traits
10.1038/s41586-025-08757-x · ExternalCitation · doi-reference
The 1000 Chinese Pangenome empowers medical and population genetics
10.1038/s41586-026-10315-y · ExternalCitation · doi-reference
Robust decomposition of cell type mixtures in spatial transcriptomics
10.1038/s41587-021-00830-w · ExternalCitation · doi-reference
Identifying phenotype-associated subpopulations by integrating bulk and single-cell sequencing data
10.1038/s41587-021-01091-3 · ExternalCitation · doi-reference
Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies
10.1038/s41588-018-0184-y · ExternalCitation · doi-reference
Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases
10.1038/s41588-020-0640-3 · ExternalCitation · doi-reference
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression
10.1038/s41588-021-00913-z · ExternalCitation · doi-reference
A cross-population atlas of genetic associations for 220 human phenotypes
10.1038/s41588-021-00931-x · ExternalCitation · doi-reference
Proteomic analysis of the periodontal pathogen Prevotella intermedia secretomes in biofilm and planktonic lifestyles
10.1038/s41598-022-09085-0 · ExternalCitation · doi-reference
Mendelian randomization
10.1038/s43586-021-00092-5 · ExternalCitation · doi-reference
METAL: fast and efficient meta-analysis of genomewide association scans
10.1093/bioinformatics/btq340 · ExternalCitation · doi-reference
Periodontitis: consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions
10.1111/jcpe.12946 · ExternalCitation · doi-reference
Burden of severe periodontitis and edentulism in 2021, with projections up to 2050: the Global Burden of Disease 2021 study
10.1111/jre.13337 · ExternalCitation · doi-reference
Diversity and scale: genetic architecture of 2068 traits in the VA Million Veteran Program
10.1126/science.adj1182 · ExternalCitation · doi-reference
Subgingival bacterial colonization profiles correlate with gingival tissue gene expression
10.1186/1471-2180-9-221 · ExternalCitation · doi-reference
Single-cell Mayo Map (scMayoMap): an easy-to-use tool for cell type annotation in single-cell RNA-sequencing data analysis
10.1186/s12915-023-01728-6 · ExternalCitation · doi-reference
Periodontal ligament stem cells in tissue remodeling: from mechanical forces to inflammatory signals
10.1186/s13287-025-04777-6 · ExternalCitation · doi-reference
Machine learning reveals microbiome differences by periodontitis severity
10.1371/journal.pone.0349686 · ExternalCitation · doi-reference
Treating chronic periodontitis: current status, challenges, and future directions
10.2147/ccide.s7712 · ExternalCitation · doi-reference
Periodontal inflammation-triggered by periodontal ligament stem cell pyroptosis exacerbates periodontitis
10.3389/fcell.2021.663037 · ExternalCitation · doi-reference
The oral microbiome in periodontal health
10.3389/fcimb.2021.629723 · ExternalCitation · doi-reference
Transcriptional activity of predominant Streptococcus species at multiple oral sites associate with periodontal status
10.3389/fcimb.2021.752664 · ExternalCitation · doi-reference
Oral bacterial community dynamics during induction of gingival inflammation
10.3389/fcimb.2025.1597690 · ExternalCitation · doi-reference
Porphyromonas gingivalis infection induces lipopolysaccharide and peptidoglycan penetration through gingival epithelium
10.3389/froh.2022.845002 · ExternalCitation · doi-reference
Oral microbiome: a review of its impact on oral and systemic health
10.3390/microorganisms12091797 · ExternalCitation · doi-reference
Quercetin reverses TNF-α induced osteogenic damage to human periodontal ligament stem cells by suppressing the NF-κB/NLRP3 inflammasome pathway
10.3892/ijmm.2021.4872 · ExternalCitation · doi-reference
Single-cell RNA landscape of the osteoimmunology microenvironment in periodontitis
10.7150/thno.65694 · ExternalCitation · doi-reference
Spatially resolved transcriptomics reveals pro-inflammatory fibroblast involved in lymphocyte recruitment through CXCL8 and CXCL10
10.7554/elife.81525 · ExternalCitation · doi-reference
