Research graph
References from Unique Oral Microbiota Signatures and Neurocognitive Function in Adolescents with and without Perinatally Acquired HIV. Local targets link to admitted publications; unresolved targets remain external evidence.
for adolescents living with perinatally acquired HIV in sub-Saharan Africa: a Collaborative Initiative for Paediatric HIV Education and Research (CIPHER) Cohort Collaboration analysis
10.1002/jia2.25044 · 2018 · External reference
African Multi-Site 2-Year Neuropsychological Study of School-Age Children Perinatally Infected, Exposed, and Unexposed to Human Immunodeficiency Virus
10.1093/cid/ciz1088 · 2020 · External reference
Impact of Perinatally Acquired HIV Disease Upon Longitudinal Changes in Memory and Executive Functioning
10.1097/qai.0000000000001441 · 2017 · External reference
HIV-Associated Cognitive Impairment in Perinatally Infected Children: A Meta-analysis
10.1542/peds.2016-0893 · 2016 · External reference
Effect of Perinatally Acquired HIV Infection on Cognitive Function and Educational Attainment in Adolescents in the Era of Antiretroviral Therapy: A Cross-sectional Study in Zimbabwe
10.1016/j.jadohealth.2025.11.014 · 2026 · External reference
Neuropsychiatric Outcomes in Children and Adolescents With Perinatally Acquired HIV: A Systematic Review and Meta-Analysis
10.1097/qai.0000000000003595 · 2025 · External reference
Socioeconomic disparities affect prefrontal function in children
10.1162/jocn.2009.21101 · 2009 · External reference
Promoting a Combination Approach to Paediatric HIV Psychosocial Support
10.1097/qad.0000000000000098 · 2013 · External reference
Unresolved reference
2020 · External reference
10.1128/msphere.00798-19
10.1128/msphere.00798-19 · 2020 · External reference
Impact of HIV on the Oral Microbiome of Children Living in Sub-Saharan Africa, Determined by Using an rpoC Gene Fragment Metataxonomic Approach
10.1128/spectrum.00871-23 · 2023 · External reference
HIV infection and exposure is associated with increased cariogenic taxa, reduced taxonomic turnover, and homogenized spatial differentiation for the supragingival microbiome
10.1186/s40168-025-02123-9 · 2025 · External reference
Oral microbiota in youth with perinatally acquired HIV infection
10.1186/s40168-018-0484-6 · 2018 · External reference
Immune status, and not HIV infection or exposure, drives the development of the oral microbiota
10.1038/s41598-020-67487-4 · 2020 · External reference
Oral microbiota in youth with perinatally acquired HIV infection
10.1186/s40168-018-0484-6 · 2018 · External reference
Unresolved reference
2025 · External reference
Oral microbiome composition, but not diversity, is associated with adolescent anxiety and depression symptoms
10.1016/j.physbeh.2020.113126 · 2020 · External reference
Profiling the oral microbiomes in patients with Alzheimer’s disease
10.1111/odi.14110 · 2023 · External reference
Unraveling the oral microbiome’s role in Alzheimer’s disease: From pathophysiology to therapeutic potential
10.1002/alz.71011 · 2025 · External reference
HIV-Associated Interactions Between Oral Microbiota and Mucosal Immune Cells: Knowledge Gaps and Future Directions
10.3389/fimmu.2021.676669 · 2021 · External reference
Association Between Oral Microbiota Dysbiosis and the Risk of Dementia: A Systematic Review
10.3390/dj13060227 · 2025 · External reference
Oral microbiome brain axis and cognitive performance in older adults
10.1038/s44400-025-00004-4 · 2025 · External reference
Multivariable association discovery in population-scale meta-omics studies
10.1371/journal.pcbi.1009442 · 2021 · External reference
B. ANOVA-like differential expression (ALDEx) analysis for mixed population RNA-Seq
10.1371/journal.pone.0067019 · 2013 · External reference
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
10.1186/s13059-014-0550-8 · 2014 · External reference
Multigroup analysis of compositions of microbiomes with covariate adjustments and repeated measures
10.1038/s41592-023-02092-7 · 2024 · External reference
Unresolved reference
External reference
Alterations in the oral microbiome in HIV-infected participants after antiretroviral therapy administration are influenced by immune status
10.1097/qad.0000000000001811 · 2018 · External reference
The oral microbiome in human immunodeficiency virus (HIV)-positive individuals
10.1099/jmm.0.000128 · 2015 · External reference
Microbiota in the oral cavity of school-age children with HIV who started antiretroviral therapy at young ages in South Africa
10.1097/qad.0000000000003599 · 2023 · External reference
Unresolved reference
2023 · External reference
Network analysis of nitrate-sensitive oral microbiome reveals interactions with cognitive function and cardiovascular health across dietary interventions
10.1016/j.redox.2021.101933 · 2021 · External reference
Distinct Oral Microbiome Signatures in Cognitive Impairment: Metagenomic Insights from the Elderly MiaGB cohort
10.1002/alz70856_101631 · 2025 · External reference
Oral microbiome and nitric oxide biomarkers in older people with mild cognitive impairment and APOE4 genotype
10.1093/pnasnexus/pgae543 · 2025 · External reference
Oral bacteriome of HIV-1-infected children from Rio de Janeiro, Brazil: Next-generation DNA sequencing analysis
10.1111/jcpe.13176 · 2019 · External reference
Pathways Linking Oral Bacteria, Nitric Oxide Metabolism, and Health
10.1177/00220345211064571 · 2022 · External reference
Divergent pro-inflammatory profile of human dendritic cells in response to commensal and pathogenic bacteria associated with the airway microbiota
10.1371/journal.pone.0031976 · 2012 · External reference
Prevotella diversity, niches and interactions with the human host
10.1038/s41579-021-00559-y · 2021 · External reference
Prevotella species as oral residents and infectious agents with potential impact on systemic conditions
10.1080/20002297.2022.2079814 · 2022 · External reference
Distinctive subgingival microbial signatures in older adults with different levels of cognitive function
10.1111/jcpe.13997 · 2024 · External reference
Oral microbiota profile is related to cognitive status in centenarians: a clinical and biological study
10.1016/j.maturitas.2025.108593 · 2025 · External reference
Oral microbiome signatures of post-stroke cognitive impairment
10.3389/fmicb.2026.1722999 · 2026 · External reference
The Interface of Oral and Brain Health: Current Insights Into the Bidirectional Relationship Between Alzheimer’s Disease and Periodontitis
10.1002/cns.70754 · 2026 · External reference
Cognitive performance in adolescents with perinatally-acquired HIV and associations with oral health in Nigeria
10.1097/qad.0000000000004429 · 2026 · External reference
Naveen Kumar, V. The oral-gut-brain axis in periodontitis: microbial signaling in systemic and neuroinflammatory disease
10.1016/j.brainres.2026.150168 · 2026 · External reference
Methionine, Homocysteine, and Methylation Levels Predict Cognitive Decline in Alzheimer’s Disease
10.1002/cns.70954 · 2026 · External reference
Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammation
10.1126/science.aan4526 · 2017 · External reference
Extensive transmission of microbes along the gastrointestinal tract
10.7554/elife.42693 · 2019 · External reference
The Oral–Gut Microbiome–Brain Axis in Cognition
10.3390/microorganisms13040814 · 2025 · External reference
The Nitrate-Nitrite-Nitric Oxide Pathway on Healthy Ageing: A Review of Pre-clinical and Clinical Data on the Impact of Dietary Nitrate in the Elderly
10.3389/fragi.2021.778467 · 2021 · External reference
Neurocognitive dysfunction in HIV-infected youth: investigating the relationship with immune activation
10.3851/imp3157 · 2017 · External reference
Immune Activation Is Associated With Neurocognitive Performance in Ugandan Adolescents Living With HIV
10.1097/qai.0000000000003483 · 2024 · External reference
HIV-Associated Cognitive Impairment in Perinatally Infected Children: A Meta-analysis
10.1542/peds.2016-0893 · 2016 · External reference
HIV-associated cognitive disorders in perinatally infected children and adolescents: a novel composite cognitive domains score
10.1080/09540121.2018.1466982 · 2018 · External reference
HIV-associated neurocognitive disorder
10.1016/s1473-3099(13)70269-x · 2013 · External reference
Evaluation of the NIH Toolbox Cognition Battery in Adolescents with HIV Infection in Zimbabwe
10.1007/s10461-026-05199-y · 2026 · External reference
Associations between epigenetic age acceleration, neurocognition, and oral health in Nigerian adolescents with and without HIV
2025 · External reference
Cognitive performance and oral health among adolescents with and without perinatal HIV infection in Nigeria
2025 · External reference
Construct Validity Supports Use of a Novel, Tablet-Based Neurocognitive Assessment for Adolescents and Young Adults Affected by Perinatal HIV from Vulnerable Communities in the United States
10.1007/s10461-020-03099-3 · 2021 · External reference
Epigenetic Aging Biomarkers Associated With Cognitive Impairment in Older African American Adults With Human Immunodeficiency Virus (HIV)
10.1093/cid/ciab563 · 2021 · External reference
A Mobile App to Screen for Neurocognitive Impairment: Preliminary Validation of NeuroScreen Among HIV-Infected South African Adults
10.2196/mhealth.9148 · 2018 · External reference
E.-S. Appraisal and characterization of candida load isolated from the oral cavity of smokers
10.1016/j.sjbs.2023.103657 · 2023 · External reference
Impact of DNA Extraction Methods on Gut Microbiome Profiles: A Comparative Metagenomic Study
10.1007/s43657-025-00232-x · 2025 · External reference
Application of different DNA extraction procedures, library preparation protocols and sequencing platforms: impact on sequencing results
10.1016/j.heliyon.2019.e02745 · 2019 · External reference
Whole Metagenome Sequencing: not Deep Enough for Complete Microbial Function Recovery
10.1101/2025.11.04.685665 · 2025 · External reference
Fast and sensitive taxonomic classification for metagenomics with Kaiju
10.1038/ncomms11257 · 2016 · External reference
Unraveling the oral microbiome’s role in Alzheimer’s disease: From pathophysiology to therapeutic potential
10.1002/alz.71011 · ExternalCitation · doi-reference
Distinct Oral Microbiome Signatures in Cognitive Impairment: Metagenomic Insights from the Elderly MiaGB cohort
10.1002/alz70856_101631 · ExternalCitation · doi-reference
The Interface of Oral and Brain Health: Current Insights Into the Bidirectional Relationship Between Alzheimer’s Disease and Periodontitis
10.1002/cns.70754 · ExternalCitation · doi-reference
Methionine, Homocysteine, and Methylation Levels Predict Cognitive Decline in Alzheimer’s Disease
10.1002/cns.70954 · ExternalCitation · doi-reference
for adolescents living with perinatally acquired HIV in sub-Saharan Africa: a Collaborative Initiative for Paediatric HIV Education and Research (CIPHER) Cohort Collaboration analysis
10.1002/jia2.25044 · ExternalCitation · doi-reference
Construct Validity Supports Use of a Novel, Tablet-Based Neurocognitive Assessment for Adolescents and Young Adults Affected by Perinatal HIV from Vulnerable Communities in the United States
10.1007/s10461-020-03099-3 · ExternalCitation · doi-reference
Evaluation of the NIH Toolbox Cognition Battery in Adolescents with HIV Infection in Zimbabwe
10.1007/s10461-026-05199-y · ExternalCitation · doi-reference
Impact of DNA Extraction Methods on Gut Microbiome Profiles: A Comparative Metagenomic Study
10.1007/s43657-025-00232-x · ExternalCitation · doi-reference
Naveen Kumar, V. The oral-gut-brain axis in periodontitis: microbial signaling in systemic and neuroinflammatory disease
10.1016/j.brainres.2026.150168 · ExternalCitation · doi-reference
Application of different DNA extraction procedures, library preparation protocols and sequencing platforms: impact on sequencing results
10.1016/j.heliyon.2019.e02745 · ExternalCitation · doi-reference
Effect of Perinatally Acquired HIV Infection on Cognitive Function and Educational Attainment in Adolescents in the Era of Antiretroviral Therapy: A Cross-sectional Study in Zimbabwe
10.1016/j.jadohealth.2025.11.014 · ExternalCitation · doi-reference
Oral microbiota profile is related to cognitive status in centenarians: a clinical and biological study
10.1016/j.maturitas.2025.108593 · ExternalCitation · doi-reference
Oral microbiome composition, but not diversity, is associated with adolescent anxiety and depression symptoms
10.1016/j.physbeh.2020.113126 · ExternalCitation · doi-reference
Network analysis of nitrate-sensitive oral microbiome reveals interactions with cognitive function and cardiovascular health across dietary interventions
10.1016/j.redox.2021.101933 · ExternalCitation · doi-reference
E.-S. Appraisal and characterization of candida load isolated from the oral cavity of smokers
10.1016/j.sjbs.2023.103657 · ExternalCitation · doi-reference
HIV-associated neurocognitive disorder
10.1016/s1473-3099(13)70269-x · ExternalCitation · doi-reference
Fast and sensitive taxonomic classification for metagenomics with Kaiju
10.1038/ncomms11257 · ExternalCitation · doi-reference
Prevotella diversity, niches and interactions with the human host
10.1038/s41579-021-00559-y · ExternalCitation · doi-reference
Multigroup analysis of compositions of microbiomes with covariate adjustments and repeated measures
10.1038/s41592-023-02092-7 · ExternalCitation · doi-reference
Immune status, and not HIV infection or exposure, drives the development of the oral microbiota
10.1038/s41598-020-67487-4 · ExternalCitation · doi-reference
Oral microbiome brain axis and cognitive performance in older adults
10.1038/s44400-025-00004-4 · ExternalCitation · doi-reference
HIV-associated cognitive disorders in perinatally infected children and adolescents: a novel composite cognitive domains score
10.1080/09540121.2018.1466982 · ExternalCitation · doi-reference
Prevotella species as oral residents and infectious agents with potential impact on systemic conditions
10.1080/20002297.2022.2079814 · ExternalCitation · doi-reference
Epigenetic Aging Biomarkers Associated With Cognitive Impairment in Older African American Adults With Human Immunodeficiency Virus (HIV)
10.1093/cid/ciab563 · ExternalCitation · doi-reference
African Multi-Site 2-Year Neuropsychological Study of School-Age Children Perinatally Infected, Exposed, and Unexposed to Human Immunodeficiency Virus
10.1093/cid/ciz1088 · ExternalCitation · doi-reference
Oral microbiome and nitric oxide biomarkers in older people with mild cognitive impairment and APOE4 genotype
10.1093/pnasnexus/pgae543 · ExternalCitation · doi-reference
Promoting a Combination Approach to Paediatric HIV Psychosocial Support
10.1097/qad.0000000000000098 · ExternalCitation · doi-reference
Alterations in the oral microbiome in HIV-infected participants after antiretroviral therapy administration are influenced by immune status
10.1097/qad.0000000000001811 · ExternalCitation · doi-reference
Microbiota in the oral cavity of school-age children with HIV who started antiretroviral therapy at young ages in South Africa
10.1097/qad.0000000000003599 · ExternalCitation · doi-reference
Cognitive performance in adolescents with perinatally-acquired HIV and associations with oral health in Nigeria
10.1097/qad.0000000000004429 · ExternalCitation · doi-reference
Impact of Perinatally Acquired HIV Disease Upon Longitudinal Changes in Memory and Executive Functioning
10.1097/qai.0000000000001441 · ExternalCitation · doi-reference
Immune Activation Is Associated With Neurocognitive Performance in Ugandan Adolescents Living With HIV
10.1097/qai.0000000000003483 · ExternalCitation · doi-reference
Neuropsychiatric Outcomes in Children and Adolescents With Perinatally Acquired HIV: A Systematic Review and Meta-Analysis
10.1097/qai.0000000000003595 · ExternalCitation · doi-reference
The oral microbiome in human immunodeficiency virus (HIV)-positive individuals
10.1099/jmm.0.000128 · ExternalCitation · doi-reference
Whole Metagenome Sequencing: not Deep Enough for Complete Microbial Function Recovery
10.1101/2025.11.04.685665 · ExternalCitation · doi-reference
Oral bacteriome of HIV-1-infected children from Rio de Janeiro, Brazil: Next-generation DNA sequencing analysis
10.1111/jcpe.13176 · ExternalCitation · doi-reference
Distinctive subgingival microbial signatures in older adults with different levels of cognitive function
10.1111/jcpe.13997 · ExternalCitation · doi-reference
Profiling the oral microbiomes in patients with Alzheimer’s disease
10.1111/odi.14110 · ExternalCitation · doi-reference
Ectopic colonization of oral bacteria in the intestine drives TH1 cell induction and inflammation
10.1126/science.aan4526 · ExternalCitation · doi-reference
10.1128/msphere.00798-19
10.1128/msphere.00798-19 · ExternalCitation · doi-reference
Impact of HIV on the Oral Microbiome of Children Living in Sub-Saharan Africa, Determined by Using an rpoC Gene Fragment Metataxonomic Approach
10.1128/spectrum.00871-23 · ExternalCitation · doi-reference
Socioeconomic disparities affect prefrontal function in children
10.1162/jocn.2009.21101 · ExternalCitation · doi-reference
Pathways Linking Oral Bacteria, Nitric Oxide Metabolism, and Health
10.1177/00220345211064571 · ExternalCitation · doi-reference
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
10.1186/s13059-014-0550-8 · ExternalCitation · doi-reference
Oral microbiota in youth with perinatally acquired HIV infection
10.1186/s40168-018-0484-6 · ExternalCitation · doi-reference
HIV infection and exposure is associated with increased cariogenic taxa, reduced taxonomic turnover, and homogenized spatial differentiation for the supragingival microbiome
10.1186/s40168-025-02123-9 · ExternalCitation · doi-reference
Multivariable association discovery in population-scale meta-omics studies
10.1371/journal.pcbi.1009442 · ExternalCitation · doi-reference
Divergent pro-inflammatory profile of human dendritic cells in response to commensal and pathogenic bacteria associated with the airway microbiota
10.1371/journal.pone.0031976 · ExternalCitation · doi-reference
B. ANOVA-like differential expression (ALDEx) analysis for mixed population RNA-Seq
10.1371/journal.pone.0067019 · ExternalCitation · doi-reference
HIV-Associated Cognitive Impairment in Perinatally Infected Children: A Meta-analysis
10.1542/peds.2016-0893 · ExternalCitation · doi-reference
A Mobile App to Screen for Neurocognitive Impairment: Preliminary Validation of NeuroScreen Among HIV-Infected South African Adults
10.2196/mhealth.9148 · ExternalCitation · doi-reference
HIV-Associated Interactions Between Oral Microbiota and Mucosal Immune Cells: Knowledge Gaps and Future Directions
10.3389/fimmu.2021.676669 · ExternalCitation · doi-reference
Oral microbiome signatures of post-stroke cognitive impairment
10.3389/fmicb.2026.1722999 · ExternalCitation · doi-reference
The Nitrate-Nitrite-Nitric Oxide Pathway on Healthy Ageing: A Review of Pre-clinical and Clinical Data on the Impact of Dietary Nitrate in the Elderly
10.3389/fragi.2021.778467 · ExternalCitation · doi-reference
Association Between Oral Microbiota Dysbiosis and the Risk of Dementia: A Systematic Review
10.3390/dj13060227 · ExternalCitation · doi-reference
The Oral–Gut Microbiome–Brain Axis in Cognition
10.3390/microorganisms13040814 · ExternalCitation · doi-reference
Neurocognitive dysfunction in HIV-infected youth: investigating the relationship with immune activation
10.3851/imp3157 · ExternalCitation · doi-reference
Extensive transmission of microbes along the gastrointestinal tract
10.7554/elife.42693 · ExternalCitation · doi-reference
